Thrombotic microangiopathies: An illustrated review [PDF]
Research and Practice in Thrombosis and Haemostasis, 2022 The thrombotic microangiopathies (TMAs) are a heterogenous group of disorders with distinct pathophysiologies that cause occlusive microvascular or macrovascular thrombosis, and are characterized by microangiopathic hemolytic anemia, thrombocytopenia ...
Mouhamed Yazan Abou‐Ismail +4 more
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Complement Mediated Endothelial Damage in Thrombotic Microangiopathies [PDF]
Frontiers in Medicine, 2022 Thrombotic microangiopathies (TMA) constitute a group of different disorders that have a common underlying mechanism: the endothelial damage. These disorders may exhibit different mechanisms of endothelial injury depending on the pathological trigger ...
Miquel Blasco +7 more
doaj +3 more sources
HELLP Syndrome and Differential Diagnosis with Other Thrombotic Microangiopathies in Pregnancy [PDF]
DiagnosticsThrombotic microangiopathies (TMAs) comprise a distinct group of diseases with different manifestations that can occur in both pediatric and adult patients.
Stefano Raffaele Giannubilo +3 more
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Eculizumab in gemcitabine-induced thrombotic microangiopathy: experience of the French thrombotic microangiopathies reference centre [PDF]
BMC Nephrology, 2021 Background Gemcitabine is a broadly prescribed chemotherapy, the use of which can be limited by renal adverse events, including thrombotic microangiopathy (TMA). Methods This study evaluated the efficacy of eculizumab, a monoclonal antibody targeting the
Maximilien Grall +14 more
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Pregnancy as a susceptible state for thrombotic microangiopathies [PDF]
Frontiers in MedicinePregnancy and the postpartum period represent phases of heightened vulnerability to thrombotic microangiopathies (TMAs), as evidenced by distinct patterns of pregnancy-specific TMAs (e.g., preeclampsia, HELLP syndrome), as well as a higher incidence of ...
Marie Frimat +5 more
doaj +3 more sources
COVID-19 and thrombotic microangiopathies. [PDF]
Thromb Res, 2021 Tiwari NR +3 more
europepmc +4 more sources
Diagnostic Testing for Differential Diagnosis in Thrombotic Microangiopathies [PDF]
Turkish Journal of Hematology, 2019 Thrombotic microangiopathies (TMAs) are multiple disease entities with different etiopathogeneses, characterized by thrombocytopenia, microangiopathic hemolytic anemia (MAHA) with schistocytosis, variable symptoms including fever, and multi-organ failure
Gina Zini, Raimondo De Cristofar
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A rare case report of gemcitabine-induced thrombotic microangiopathies [PDF]
SAGE Open Medical Case Reports, 2021 A 65-year-old female patient with breast cancer and soft tissue sarcoma who experienced a gemcitabine-induced thrombotic microangiopathies manifestation visited the emergency department.
Mohammed Ali Madkhali
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Thrombotic microangiopathies assessment: mind the complement. [PDF]
Clin Kidney J, 2021 When faced with microangiopathic haemolytic anaemia, thrombocytopenia and organ dysfunction, clinicians should suspect thrombotic microangiopathy (TMA). The endothelial damage that leads to this histological lesion can be triggered by several conditions ...
Blasco M +9 more
europepmc +2 more sources
MASP2 levels are elevated in thrombotic microangiopathies: association with microvascular endothelial cell injury and suppression by anti-MASP2 antibody narsoplimab. [PDF]
Clin Exp Immunol, 2021 Involvement of the alternative complement pathway (AP) in microvascular endothelial cell (MVEC) injury characteristic of a thrombotic microangiopathy (TMA) is well documented.
Elhadad S +5 more
europepmc +2 more sources