Results 11 to 20 of about 1,097,810 (322)

Throughput and Delay Optimality of Power-of-d Choices in Inhomogeneous Load Balancing Systems [PDF]

open access: yesOperations Research Letters 2021, Volume 49, Issue 4, Pages 616-622, 2020
It is well-known that the power-of-d choices routing algorithm maximizes throughput and is heavy-traffic optimal in load balancing systems with homogeneous servers. However, if the servers are heterogeneous, throughput optimality does not hold in general.
arxiv   +1 more source

The Role of Non-Coding RNAs in the Human Placenta

open access: yesCells, 2022
Non-coding RNAs (ncRNAs) play a central and regulatory role in almost all cells, organs, and species, which has been broadly recognized since the human ENCODE project and several other genome projects.
Milena Žarković   +3 more
doaj   +1 more source

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

open access: yesNucleic Acids Research, 2010
High-throughput sequencing platforms are generating massive amounts of genetic variation data for diverse genomes, but it remains a challenge to pinpoint a small subset of functionally important variants.
Kai Wang, Mingyao Li, H. Hakonarson
semanticscholar   +1 more source

Association between LRP1 C766T polymorphism and Alzheimer’s disease susceptibility: a meta-analysis

open access: yesScientific Reports, 2017
Low density lipoprotein receptor-related protein 1 (LRP1) C766T polymorphism (rs1799986) has been extensively investigated for Alzheimer’s disease (AD) susceptibility. However, results in different studies have been contradictory. Therefore, we conducted
Yun Wang   +9 more
doaj   +1 more source

Integrative prediction of gene expression with chromatin accessibility and conformation data

open access: yesEpigenetics & Chromatin, 2020
Background Enhancers play a fundamental role in orchestrating cell state and development. Although several methods have been developed to identify enhancers, linking them to their target genes is still an open problem. Several theories have been proposed
Florian Schmidt   +2 more
doaj   +1 more source

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

open access: yesBioinform., 2013
MOTIVATION Molecular simulation has historically been a low-throughput technique, but faster computers and increasing amounts of genomic and structural data are changing this by enabling large-scale automated simulation of, for instance, many conformers ...
S. Pronk   +11 more
semanticscholar   +1 more source

COMP Report: CPQR technical quality control guidelines for use of positron emission tomography/computed tomography in radiation treatment planning

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Positron emission tomography with x‐ray computed tomography (PET/CT) is increasingly being utilized for radiation treatment planning (RTP). Accurate delivery of RT therefore depends on quality PET/CT data. This study covers quality control (QC) procedures required for PET/CT for diagnostic imaging and incremental QC required for RTP.
Ran Klein   +7 more
wiley   +1 more source

High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries

open access: yesNature Communications, 2017
A fundamental question in microbiology is whether there is continuum of genetic diversity among genomes, or clear species boundaries prevail instead. Whole-genome similarity metrics such as Average Nucleotide Identity (ANI) help address this question by ...
Chirag Jain   +4 more
semanticscholar   +1 more source

Validation of pencil beam scanning proton therapy with multi‐leaf collimator calculated by a commercial Monte Carlo dose engine

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract This study aimed to evaluate the clinical beam commissioning results and lateral penumbra characteristics of our new pencil beam scanning (PBS) proton therapy using a multi‐leaf collimator (MLC) calculated by use of a commercial Monte Carlo dose engine.
Yuki Tominaga   +5 more
wiley   +1 more source

Greening automation: Wash and Re-use of disposable 384-well liquid handling tips to enable sustainable high-throughput vaccine development

open access: yesSLAS Technology, 2023
Laboratory automation uses large amounts of plastic consumables, generating substantial single-use plastic waste. Automated ELISAs are an indispensable analytical tool in vaccine formulation and process development.
Brittney Pedrazzi   +7 more
doaj  

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