Results 41 to 50 of about 1,606,013 (337)
Polyphenol-Based Design of Functional Olive Leaf Infusions
Food Technology and Biotechnology, 2019 The beneficial properties of polyphenols are widely recognized, and polyphenol-rich olive oil, which is part of the typical Mediterranean diet, has been identified as having positive health effects.
Željka Peršurić +3 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Exploring the impact of primer length on efficient gene detection via high-throughput sequencing
Nature CommunicationsReverse transcription (RT) is a crucial step in most RNA analysis methods. Optimizing protocols for this initial stage is critical for effective target detection, particularly when working with limited input RNA.
Julia Micheel +3 more
doaj +1 more source
Metals, 2023 There is a huge demand for high-performance materials in extreme environments involving wear and corrosion. High chromium white cast irons (HCWCIs) display better performance than many materials since they are of sufficient hardness for wear protection ...
Simbarashe Fashu, Vera Trabadelo
doaj +1 more source
Caching Gain in Wireless Networks with Fading: A Multi-User Diversity Perspective
, 2013 We consider the effect of caching in wireless networks where fading is the dominant channel effect. First, we propose a one-hop transmission strategy for cache-enabled wireless networks, which is based on exploiting multi-user diversity gain.
Khalaj, Babak Hossein +2 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Novel Antiretroviral Structures from Marine Organisms
Molecules, 2019 In spite of significant advancements and success in antiretroviral therapies directed against HIV infection, there is no cure for HIV, which scan persist in a human body in its latent form and become reactivated under favorable conditions.
Karlo Wittine +3 more
doaj +1 more source
A General Class of Throughput Optimal Routing Policies in Multi-hop Wireless Networks
, 2011 This paper considers the problem of throughput optimal routing/scheduling in a multi-hop constrained queueing network with random connectivity whose special case includes opportunistic multi-hop wireless networks and input-queued switch fabrics. The main
Javidi, Tara +2 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source