Results 41 to 50 of about 1,985,368 (271)

Cost Estimation Tool for Metallic Parts Made by Casting: A Case Study

open access: yesMetals, 2023
This work presents a mathematical tool to estimate the cost of fabricating pumps by traditional casting. The drivers that most affect the cost of the process are identified in each step of the procedure, i.e., material, labour, energy, tools and general ...
Itziar Iraola-Arregui   +2 more
doaj   +1 more source

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

open access: yesBioinform., 2012
Heterogeneity and latent variables are now widely recognized as major sources of bias and variability in high-throughput experiments. The most well-known source of latent variation in genomic experiments are batch effects-when samples are processed on ...
J. Leek   +4 more
semanticscholar   +1 more source

High-throughput proteomics: a methodological mini-review

open access: yesLaboratory Investigation, 2022
Proteomics plays a vital role in biomedical research in the post-genomic era. With the technological revolution and emerging computational and statistic models, proteomic methodology has evolved rapidly in the past decade and shed light on solving ...
Miao Cui, Chao Cheng, Lanjing Zhang
semanticscholar   +1 more source

High Throughput Drug Profiling [PDF]

open access: yesJournal of the Association for Laboratory Automation, 2000
High throughput screening has significantly contributed to advances in drug discovery. The great increase in the number of samples screened has been accompanied by increases in costs and in the data required for the investigated compounds. High throughput profiling addresses the issues of compound selectivity and specificity.
Michael Entzeroth   +3 more
openaire   +6 more sources

Ribosomal Database Project: data and tools for high throughput rRNA analysis

open access: yesNucleic Acids Res., 2013
Ribosomal Database Project (RDP; http://rdp.cme.msu.edu/) provides the research community with aligned and annotated rRNA gene sequence data, along with tools to allow researchers to analyze their own rRNA gene sequences in the RDP framework.
J. Cole   +9 more
semanticscholar   +1 more source

Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in vivo

open access: yesFrontiers in Pharmacology, 2018
Unique and outstanding physical and chemical properties of zeolite materials make them extremely useful in a variety of applications including agronomy, ecology, manufacturing, and industrial processes.
Sandra Kraljević Pavelić   +6 more
doaj   +1 more source

Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms

open access: yesThe ISME Journal, 2012
DNA sequencing continues to decrease in cost with the Illumina HiSeq2000 generating up to 600 Gb of paired-end 100 base reads in a ten-day run. Here we present a protocol for community amplicon sequencing on the HiSeq2000 and MiSeq Illumina platforms ...
J. Caporaso   +15 more
semanticscholar   +1 more source

High throughput screening of 0.5 million compounds against CRAF using Alpha CETSAⓇ

open access: yesSLAS Discovery, 2023
The cellular thermal shift assay (CETSA®) has increasingly been used in early drug discovery to provide a measure of cellular target engagement. Traditionally, CETSA has been employed for bespoke questions with small to medium throughput and has ...
Hannah Rowlands   +9 more
doaj  

DIA-NN: Neural networks and interference correction enable deep proteome coverage in high throughput

open access: yesNature Methods, 2019
We present an easy-to-use integrated software suite, DIA-NN, that exploits deep neural networks and new quantification and signal correction strategies for the processing of data-independent acquisition (DIA) proteomics experiments.
V. Demichev   +4 more
semanticscholar   +1 more source

Novel Antiretroviral Structures from Marine Organisms

open access: yesMolecules, 2019
In spite of significant advancements and success in antiretroviral therapies directed against HIV infection, there is no cure for HIV, which scan persist in a human body in its latent form and become reactivated under favorable conditions.
Karlo Wittine   +3 more
doaj   +1 more source

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