Results 221 to 230 of about 151,527 (300)

Impact of Thymidine Loop Modifications on Telomeric G-Quadruplex Catalytic Systems for Asymmetric Sulfoxidation. [PDF]

Molecules
Finamore C, Festa C, Benigno D, Aliberti C, Barbato R, De Marino S, Galeone A, Esposito V, Virgilio A.   +8 more
europepmc   +1 more source

From Pharmacodynamic Biomarker to Evaluating Treatment Response: Biomarkers in Primary Mitochondrial Diseases

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Primary mitochondrial diseases (PMDs) result from genetic variants in nuclear DNA and mitochondrial DNA which commonly lead to aberrant oxidative phosphorylation. The clinical complexity, often attributed to the underlying genetics, includes several distinct syndromes (e.g., Barth syndrome; Pearson syndrome; Mitochondrial encephalomyopathy ...
Sydney Stern, Karryn Crisamore, John Patton, Robert Schuck, Michael Pacanowski   +4 more
wiley   +1 more source

Mitotic BLM functions are required to maintain genomic stability. [PDF]

Nucleic Acids Res
Hamann TE, Wieland A, Mohseni F, Vukušić K, Tirincsi A, Wardenaar R, Losito M, Harmsen I, Gönenc II, Wollnik B, Foijer F, Tolić IM, Storchová Z, Räschle M.   +13 more
europepmc   +1 more source

Proteomic Profiling of Plasma to Uncover Novel Intervention Targets and Prognostic Biomarkers for Chronic Liver Diseases

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5029-5042, June 2026.
ABSTRACT Aims The burden of chronic liver disease (CLD) is increasing. This study aims to identify protein markers for CLD and its progression, and develop a protein‐based risk prediction model. Materials and Methods We used proteome‐wide Mendelian randomization (MR), Bayesian colocalization and summary‐data‐based MR with proteomic data from deCODE ...
Xinxuan Li, Jing Sun, Jianhui Zhao, Fangyuan Jiang, Meng Zhang, Hao Wu, Shuai Yuan, Xue Li, Juan Lu, Christos S. Mantzoros   +9 more
wiley   +1 more source

Regulation of Citron kinase by CDK1 and Aurora B regulates midbody formation and stability. [PDF]

J Cell Sci
Capalbo L, Halcrow EFJ, Bassi ZI, D'Avino PP.   +3 more
europepmc   +1 more source

Plant organelle C‐to‐U RNA editing factors can operate successfully in yeast (Saccharomyces cerevisiae) as an easily amenable eukaryotic system for their functional analysis

The FEBS Journal, Volume 293, Issue 11, Page 3166-3186, June 2026.
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan, Annika Hanraths, Jingchan Xie, Mareike Schallenberg‐Rüdinger, Volker Knoop   +4 more
wiley   +1 more source

Loss of JAK1 Function Causes G2-M Cell-Cycle Defects Vulnerable to KIF18A Inhibition. [PDF]

Cancer Res
Kelley VM, Baro M, Gasperi WE, Ader NR, Lea H, Lee H, Phoomak C, Kabeche L, King MC, Contessa JN.   +9 more
europepmc   +1 more source

Comparative evaluation of noncanonical amino acids as site‐specific NMR probes for the complex of E. coli SSB with single‐stranded DNA without isotope labelling

The FEBS Journal, Volume 293, Issue 12, Page 3601-3620, June 2026.
Genetic encoding of noncanonical amino acids (ncAA) enables their site‐specific installation in proteins. This work compares the nuclear magnetic resonance (NMR) performance of different ncAAs in a large protein−DNA complex (~ 100 kDa) without isotope labelling. The ncAAs deliver readily detectable NMR signals in the complex between E.
Sreelakshmi Mekkattu Tharayil, Haocheng Qianzhu, Elwy H. Abdelkader, Adarshi P. Welegedara, Josemon George, Christoph Nitsche, Thomas Huber, Gottfried Otting   +7 more
wiley   +1 more source

Anti-CD4 antibody-modulated transplants for GVHD prevention in hematopoietic cell transplantation.

Blood
Roth K, Loeffler D, Blumert C, Scholz A, Reiche K, Bauer M, Wickenhauser C, Schiefer D, Hilger N, Blaudszun AR, Thees J, Walter J, Tretbar US, Koehl U, Fricke S, Blache U.   +15 more
europepmc   +1 more source

Interaction of IRS2 with PLK1 protects cells from mitotic stress. [PDF]

Cell Death Dis
Lee JS, Bui QT, Jo M, Morgan JS, Nasa I, Kettenbach AN, Shaw LM.   +6 more
europepmc   +1 more source