Results 91 to 100 of about 41,566 (244)

Interactions entre les thymocytes et les cellules epitheliales de la medulla thymique. (interactions between thymocytes and thymic medullary epithelial cells.) [PDF]

open access: yes, 1988
Direct lympho-stromal interactions constitutes an intrinsic part of T-cell differentiation. However the precise role of cellular complexes is far from clear. The objective of the present work was to gain an insight into this question.
Hugo, Patrice
core  

Role of regulatory T cells in immune tolerance [PDF]

open access: yes, 2009
In this present work, we investigated the role of dendritic cells (DC) and regulatory T cells (Treg) in immune tolerance as well as their potential in the treatment of autoimmune or graft versus host (GvH) diseases.
Swee, Lee Kim
core   +1 more source

Lack of Galectin-3 Disrupts Thymus Homeostasis in Association to Increase of Local and Systemic Glucocorticoid Levels and Steroidogenic Machinery

open access: yesFrontiers in Endocrinology, 2018
Maintenance of thymus homeostasis is a delicate interplay involving hormones, neurotransmitters and local microenvironmental proteins, as well as saccharides, acting on both thymocytes and stromal cells.
Ednéa Oliveira-de-Abreu   +14 more
doaj   +1 more source

Role of miRNAs in Normal and Myasthenia Gravis Thymus

open access: yesFrontiers in Immunology, 2020
The thymus, a primary lymphoid organ, provides a complex environment essential for the generation of the T-cell repertoire. Thymic alterations occur during life either in the context of thymic involution upon aging or the pathophysiological context of ...
Mélanie A. Cron   +3 more
doaj   +1 more source

A real‐world study on different initiation times and treatment durations of letermovir for cytomegalovirus prophylaxis after allogeneic haematopoietic stem cell transplantation

open access: yesBritish Journal of Haematology, EarlyView.
Early letermovir initiation (day 0) after allogeneic haematopoietic stem cell transplantation (allo‐HSCT) reduced early cytomegalovirus (CMV) infection and delayed first CMV DNAemia compared with later starts. Extending prophylaxis to 200 days virtually eliminated late CMV reactivation and improved 1‐year overall survival, with no grade ≥3 drug‐related
Shiyu Chen   +4 more
wiley   +1 more source

Immune features of graft‐derived mucosal‐associated invariant T cells predict gastrointestinal graft‐versus‐host disease

open access: yesBritish Journal of Haematology, EarlyView.
Summary Gastrointestinal acute graft‐versus‐host disease (GI aGVHD) remains a major complication after allogeneic haematopoietic stem cell transplantation (allo‐HSCT), and early risk identification and intervention are essential for improving outcomes.
Gao Mengge   +8 more
wiley   +1 more source

Flow Cytometric Analysis of Mediastinal Masses in Cats: A Retrospective Study

open access: yesFrontiers in Veterinary Science, 2020
Mediastinal masses occur in dogs and cats and are often investigated with cytology. However, discrimination between the two most common lesions (thymoma and lymphoma) may be challenging, especially when small/medium lymphocytes represent the prevalent ...
Serena Bernardi   +8 more
doaj   +1 more source

RAMP2, CLR and AM distribution in cultured thymocytes. [PDF]

open access: yes, 2014
(A) Immunofluorescence staining of thymocytes co-cultured with TECs for RAMP2 (green) and AM (blue). Only some thymocytes express RAMP2 and AM, mainly in the cytoplasmic compartment (one of them indicated by a red arrow), whereas other cells are not ...
Giada Perdoncin (564981)   +13 more
core   +1 more source

The corepressor NCOR1 regulates the survival of single-positive thymocytes [PDF]

open access: yes, 2017
Nuclear receptor corepressor 1 (NCOR1) is a transcriptional regulator bridging repressive chromatin modifying enzymes with transcription factors. NCOR1 regulates many biological processes, however its role in T cells is not known.
Nicole Boucheron   +23 more
core   +3 more sources

Thymocyte migration and emigration

open access: yesImmunology Letters
Hematopoietic precursors (HPCs) entering into the thymus undergo a sequential process leading to the generation of a variety of T cell subsets. This developmental odyssey unfolds in distinct stages within the thymic cortex and medulla, shaping the landscape of T cell receptor (TCR) expression and guiding thymocytes through positive and negative ...
Qingyue Tong   +4 more
openaire   +2 more sources

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