Results 101 to 110 of about 45,812 (254)
Abstract Background Despite pre‐emptive treatment (PeT), cytomegalovirus (CMV) disease and reactivation remain a clinical concern. In Australia and New Zealand (ANZ), variability exists in the management of CMV for haematopoietic stem cell transplantation (HSCT) recipients.
Andrea Henden +13 more
wiley +1 more source
Formaldehyde-Induced Shrinkage of Rat Thymocytes
To test the possibility that micromolar formaldehyde, a metabolite of methanol derived from aspartame, exerts cytotoxicity, its effect on rat thymocytes was examined under the in vitro condition using a flow cytometer.
Mami Nakata +5 more
core +1 more source
Role of regulatory T cells in immune tolerance [PDF]
In this present work, we investigated the role of dendritic cells (DC) and regulatory T cells (Treg) in immune tolerance as well as their potential in the treatment of autoimmune or graft versus host (GvH) diseases.
Swee, Lee Kim
core +1 more source
Aire and Fezf2 Shape the Medullary Thymic Epithelial Cell Immunopeptidome for Central Tolerance
Central tolerance is shaped not merely by promiscuous gene expression in medullary thymic epithelial cells (mTECs), but by the subset of self‐peptides ultimately presented on MHC class II molecules. We propose a multilayered framework in which AIRE/Aire and FEZF2/Fezf2, together with specialised differentiation programmes—including thymic mimetic‐cell ...
Geraldo Aleixo Passos +5 more
wiley +1 more source
human thymocytes with high CXCR4-induced chemotaxis
GLUT1, the major glucose transporter in peripheral T lymphocytes, is induced upon T cell receptor activation. However, the role of GLUT1 during human thymocyte differentiation remains to be evaluated.
Sitbon, M. +13 more
core +1 more source
Autoimmunity and Periodontitis
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
Influence of human thymocytes on B-lymphocyte differentiation in man
Human thymocytes from children less than 6 years of age were tested for their influence on differentiation of normal B cells. The addition of either thymocytes or a culture supernatant from thymocytes to normal peripheral blood lymphocytes (PBL) enhanced
Smithwick, Elizabeth +9 more
core +1 more source
Recipient–Donor Sex Combinations and Posttransplant Infections: A Swiss Transplant Cohort Study
In this cohort study of 5033 patients, only the recipient sex, in particularly kidney recipients, was independently associated with an increased risk of infections, when compared to males. These findings indicate that recipient–donor sex combination does not influence short‐term solid organ transplantation outcome.
Christian T. J. Magyar +16 more
wiley +1 more source
MeV infection of thymocytes in TOC.
TOCs from a 1 year-old child were inoculated with Chi-1 or control media at 2×10−4 pfu/cell and the MeV N protein expression in thymocytes was monitored for 6 days.
Luca A. Vricella (306425) +3 more
core +1 more source

