Results 81 to 90 of about 45,812 (254)

Optimizing cord blood unit selection to improve survival after single‐unit unrelated cord blood transplantation for adult myelodysplastic syndrome

British Journal of Haematology, EarlyView.
Summary Unrelated cord blood transplantation (CBT) is an important alternative donor option for adult patients with myelodysplastic syndrome (MDS); however, the prognostic significance of cord blood unit characteristics following CBT remains unclear and may vary according to disease risk.
Takaaki Konuma, Machiko Fujioka, Kyoko Fuse, Tatsuya Suwabe, Hiroki Hosoi, Naoyuki Uchida, Masatsugu Tanaka, Kazuto Ogura, Satoshi Takahashi, Makoto Onizuka, Takeshi Maeda, Noriko Doki, Yasufumi Uehara, Atsushi Wake, Masatoshi Sakurai, Naoyuki Anzai, Toshimitsu Ueki, Yoshiko Matsuhashi, Koji Kawamura, Fumihiko Ishimaru, Junya Kanda, Marie Ohbiki, Yoshiko Atsuta, Hidehiro Itonaga   +23 more
wiley   +1 more source

Flow Cytometric Analysis of Mediastinal Masses in Cats: A Retrospective Study

Frontiers in Veterinary Science, 2020
Mediastinal masses occur in dogs and cats and are often investigated with cytology. However, discrimination between the two most common lesions (thymoma and lymphoma) may be challenging, especially when small/medium lymphocytes represent the prevalent ...
Serena Bernardi, Serena Bernardi, Valeria Martini, Valeria Martini, Stefano Perfetto, Marzia Cozzi, Marzia Cozzi, Stefano Comazzi, Stefano Comazzi   +8 more
doaj   +1 more source

Reduced‐dose versus standard‐dose total body irradiation before allogeneic haematopoietic stem cell transplantation in adults with acute lymphoblastic leukaemia

British Journal of Haematology, EarlyView.
Summary Comparative data on reduced‐dose (8 Gy) versus standard‐dose (12 Gy) total body irradiation (TBI) before allogeneic haematopoietic stem cell transplantation (allo‐HSCT) for adults with acute lymphoblastic leukaemia (ALL) remain limited. We retrospectively analysed 101 adults undergoing first allo‐HSCT between 1999 and 2024 after 8 Gy or 12 Gy ...
Isabella Gruber, Matthias Edinger, Hendrik Poeck, Elisabeth Meedt, Ernst Holler, Wolfgang Herr, Oliver Koelbl, Daniel Wolff   +7 more
wiley   +1 more source

Casp9DN reduces ROS levels in primary thymocytes.

, 2013
A) Representative histogram overlays of DHE stained viable thymocytes is shown. All cells were treated with or without Dex as indicated. Caspase activity was inhibited by either Casp9DN expression (red line, Casp9DN) or Q-VD-OPh treatment (blue line, WT ...
Sih-han Wang (351494), Sean M. Martin (300953), C. Michael Knudson (89096), Peter S. Harris (351495)   +3 more
core   +1 more source

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu, Lisa Zimmer, Dimitra Vlachopoulou, Elias Haj‐Yehia, Julia Hoffmann, Lars Michel, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Matthias Totzeck, Tienush Rassaf   +10 more
wiley   +1 more source

ADAM8^−/− thymi have increased numbers of thymocytes.

, 2013
Numbers of (A) early thymic progenitors (ETP: DN1 ckit+), (B) DN thymocytes, (C) DP thymocytes, (D) CD4 and CD8 thymocytes, (E) semi and late mature CD4 thymocytes and (F) semi and late mature CD8 thymocytes in wt and ADAM8−/− thymi.
Klaus Gossens (376981), Silvia Naus (361705), Georg A. Holländer (79665), Hermann J. Ziltener (361706)   +3 more
core   +1 more source

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang, Melanie Ricke‐Hoch, David Duncker, Johann Bauersachs, Dominik Berliner   +4 more
wiley   +1 more source

Increased CV of inducible CD69 expression in Dicer-deficient thymocytes.

, 2015
A) Activation of CD4+ CD8+ DP thymocytes (oval, top) results in CD69 expression (horizontal line defines CD69+ cells, middle) and definition of CD69hi cells (oval, bottom).
Amanda G. Fisher (78180), Matthias Merkenschlager (47289), Chang-Zheng Chen (144232), Ludovica Bruno (695994), Antoine Marcais (695995), Christina Loh (166647), Azra Krek (695997), James Elliott (349601), Arnulf Hertweck (695996), Rory Blevins (695993), Thomas Carroll (375358), Nikolaus Rajewsky (3246)   +11 more
core   +1 more source

Transgene is not expressed in thymocytes.

, 2017
(A) eGFP mRNA levels in thymocytes and thymic stroma of uninduced-K18 mice by RT-PCR. Thymocytes was released by gently applying pressure on thymus between two frosted glass slides, and then FACS-sorted for CD45+ cells.
Sophie Wang (1415950), T. Norene O’Sullivan (491939), Diana C. Haines (491941), Terry Van Dyke (2227), Kimberly Klarmann (3716482), Debra Gilbert (491938), Lucy Lu (2708), Teresa Sullivan (3716485), Jonathan R. Keller (3716479), Yurong Song (491937)   +9 more
core   +1 more source

An Electron Microscopic Study on the Effects of Prostaglandin F2a (PG F2a) and Fenugreek Extract on Thymocytes in Thymus Gland

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2019
This study was done to clarify the effects of PGF2a on thymocytes in rat thymus gland, and the possibility of minimizing its effects by using fenugreek extract.
K. S. N. Al-Kaisy
doaj