Results 21 to 30 of about 41,566 (244)
Journal of Traditional Chinese Medical Sciences, 2018 Objective: To determine the effect of an immunosuppressive active component (periploside A) isolated from the stem bark of Periplocae Cortex (Periploca sepium Bge.), a Chinese medicinal herb used in the treatment of rheumatoid arthritis for centuries in ...
Huifang Deng +8 more
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The sensitivity of cells with the various level of NAD(P)H:quinone oxidoreductase 1 to cytotoxic action of quinonimines and α-тоcopherol synthetic derivatives [PDF]
The Ukrainian Biochemical Journal, 2015 The effects of α-tocopherol with shortened to 6 carbon atoms side chain (α-Toc-C6), α-tocopherol succinate (α-TS) and quinonimine 2,6-dichlorophenolindophenol (DCPIP) on DT-diaphorase activity and viability of rat thymocytes, splenocytes and hepatocytes ...
G. V. Petrova, А. V. Parshykov
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Proteasome activities decrease during dexamethasone-induced apoptosis of thymocytes [PDF]
, 1998 The induction of apoptosis in thymocytes by the glucocorticoid dexamethasone was used as a model system to investigate whether there are changes in 20 S and 26 S proteasome activities during apoptosis.
Murray, Rachael +9 more
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Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development [PDF]
, 2011 Dendritic cells (DCs) in the thymus (tDCs) are predominantly accumulated in the medulla and contribute to the establishment of self-tolerance. However, how the medullary accumulation of tDCs is regulated and involved in self-tolerance is unclear. We show
Ishimaru, N. +36 more
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Neoplasia: An International Journal for Oncology Research, 2008 Both oxidative stress and endoplasmic reticulum (ER) stress have been implicated in carcinogenesis. It is well documented that cells deficient in the ataxia-telangiectasia mutated (ATM) gene undergo oxidative stress, which is critically involved in ...
Mingshan Yan +6 more
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Calcium Signaling Is Impaired in PTEN-Deficient T Cell Acute Lymphoblastic Leukemia
Frontiers in Immunology, 2022 PTEN (Phosphatase and TENsin homolog) is a well-known tumor suppressor involved in numerous types of cancer, including T-cell acute lymphoblastic leukemia (T-ALL). In human, loss-of-function mutations of PTEN are correlated to mature T-ALL expressing a T-
Saran Pankaew +9 more
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Expression of genes encoding cytotoxic cell-associated serine proteases in thymocytes [PDF]
, 1990 A family of homologous serine esterases designated granzyme A-H and the pore-forming protein perforin are present in cytoplasmic granules of mature peripheral cytolytic T lymphocytes and natural killer cells.
Macdonald, H. Robson +5 more
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eLife, 2019 CD4 and CD8 T cells are vital components of the immune system. We found that histone deacetylase 3 (HDAC3) is critical for the development of CD4 T cells, as HDAC3-deficient DP thymocytes generate only CD8SP thymocytes in mice.
Rachael Laura Philips +8 more
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CD4 SP thymocytes, but not CD8 SP or DP thymocytes, store and mobilize pCD40L. [PDF]
, 2012 A, Gating strategy for identifying CD8 SP, DP, and immature and mature CD4 SP thymocytes. B–E, Mobilization of pCD40L for immature (B) and mature (C) CD4 SP thymocytes, CD8 SP (D), and DP (E) thymocytes. Cd40lg−/− : CD40L-deficient mouse.
David B. Jacoby (182049) +7 more
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A novel activity on thymocytes cells exerted by the rattlesnake (Crotalus durissus cumanensis) venom
Biomédica: revista del Instituto Nacional de Salud, 2021 Introduction: The thymus is active mainly during the neonatal and pre-adolescent periods. Objective: To test naïve thymocytes proliferation and monocytes stimulation. Materials and methods: We collected fresh thymus tissue from neonate mice after surgery.
María M. Pulido-Méndez +2 more
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