Results 51 to 60 of about 41,566 (244)
The effects of intracerebroventricularly applied ghrelin on thymocytes and thymic architecture in rats of different ages [PDF]
Archives of Biological Sciences, 2020 Ghrelin positively influences the total number of thymocytes and size of the thymus in 14-, 20- and 24-month-old rats. We examined the effect of centrally-applied ghrelin on thymus weight and structure in Wistar rats of different ages. The study included
Todorović Jovana S. +5 more
doaj +1 more source
Defects in Thymocyte Differentiation and Thymocyte‐ Stromal Interactions in the Trisomy 16 Mouse [PDF]
Journal of Immunology Research, 1992 We have examined fetal thymic development in the trisomy 16 (Ts16) mouse, which is considered to be a model for human trisomy 21, or Down Syndrome. The Ts16 thymus contains 10 to 20% of the number of lymphocytes found in a normal thymus at a comparable stage.
Ewart, Janet L., Auerbach, Robert
openaire +2 more sources
Increased CV of inducible CD69 expression in Dicer-deficient thymocytes. [PDF]
, 2015 A) Activation of CD4+ CD8+ DP thymocytes (oval, top) results in CD69 expression (horizontal line defines CD69+ cells, middle) and definition of CD69hi cells (oval, bottom).
Amanda G. Fisher (78180) +11 more
core +1 more source
The thymus and T-cell ontogeny in ballan wrasse (Labrus bergylta) is nutritionally modelled
Frontiers in Immunology, 2023 Marine fish larvae often experience high mortality unrelated to predation during early life stages, and farmed ballan wrasse (Labrus bergylta) is no exception.
Angela Etayo +6 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
N3/LacZ reporter expression in DN3 thymocytes. [PDF]
, 2013 (A) Lin- DN thymocytes from N3LacZ/LacZ and N3+/+ mice were loaded with FDG and stained with anti-CD25-APC, anti-CD71-biotin, and anti-CD117-APCCy7 followed by Avidin-PECy5.
Greg Chang (344389) +7 more
core +1 more source
Impact of in vitro HIV infection on human thymic regulatory T cell differentiation
Frontiers in Microbiology, 2023 BackgroundThe differentiation and function of immunosuppressive regulatory T cells (Tregs) is dictated by the master transcription factor FoxP3. During HIV infection, there is an increase in Treg frequencies in the peripheral blood and lymphoid tissues ...
Sharada Swaminathan +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Friedreich Ataxia (FRDA) is a neurodegenerative disorder of children and young adults associated with cardiomyopathy and other systemic complications. We report a 10‐year‐old girl who presented simultaneously with Acute Myelogenous Leukemia and FRDA who was successfully treated for her leukemia with allogeneic hematopoietic stem cell ...
Alexandra Gitman +5 more
wiley +1 more source
Vav regulates peptide-specific apoptosis in thymocytes. [PDF]
, 1998 The protooncogene Vav functions as a GDP/GTP exchange factor (GEF) for Rho-like small GTPases involved in cytoskeletal reorganization and cytokine production in T cells.
Mariathasan, S +19 more
core +1 more source
Is the thymus a target organ in infectious diseases?
Memorias do Instituto Oswaldo Cruz, 1992 The thymus is a central lymphoid organ, in wich T cell precursors differentiale and generate most of the so-called T cell reprtoire. Along with a variety of acute infectious diseases, we and others determined important changes in both microenvironmental ...
Wilson Savino +5 more
doaj +1 more source