Results 61 to 70 of about 32,913 (197)
Magnetic Resonance Imaging as a Complementary Diagnostic Tool for Aplastic Anemia
American Journal of Hematology, EarlyView.
Jeanette Walter +6 more
wiley +1 more source
Precision Medical Sciences, EarlyView.TNFRSF members orchestrate a dynamic immunoregulatory network in lung cancer by coordinating co‐stimulatory and inhibitory signaling across immune cell populations, highlighting their potential as targets for precision immunotherapy. Abstract Immune checkpoint blockade has fundamentally reshaped the therapeutic landscape of lung cancer.
Bingjie Xue +3 more
wiley +1 more source
Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping
Environmental Toxicology, EarlyView.ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira +8 more
wiley +1 more source
Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development
Environmental Toxicology, EarlyView.ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo +10 more
wiley +1 more source
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2019 This study was done to clarify the effects of PGF2a on thymocytes in rat thymus gland, and the possibility of minimizing its effects by using fenugreek extract.
K. S. N. Al-Kaisy
doaj
British Journal of Haematology, EarlyView.Summary Teenage and young adult (TYA) patients undergoing allogeneic stem cell transplant have distinct psychosocial needs, yet they are poorly represented in research and their outcomes are not well understood. This study uses prospectively collected data from the British Society of Blood and Marrow Transplantation and Cellular Therapy (BSBMTCT ...
Graham McIlroy +15 more
wiley +1 more source
Limited roles of the miR‐17‐92 cluster in the regulation of T‐cell apoptosis
The FEBS Journal, EarlyView.The pro‐apoptotic protein BIM shapes T‐cell survival and function, but how it is regulated remains unclear. In a mouse model lacking direct miR‐17‐92:Bim interactions, we observed a moderate reduction in Th17 CD4+ T cells. BIM levels were modestly increased in double‐positive thymocytes and naive CD8+ T cells, but this did not affect overall T‐cell ...
Katharina Hoppe +7 more
wiley +1 more source
Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders
The FEBS Journal, EarlyView.Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo +6 more
wiley +1 more source
Frontiers in Immunology, 2019 The thymus plays a fundamental role in establishing and maintaining central and peripheral tolerance and defects in thymic architecture or AIRE expression result in the development of autoreactive lymphocytes.
Genni Enza Marcovecchio +29 more
doaj +1 more source