Results 91 to 100 of about 26,995 (192)

Highly Tigecycline-Resistant Klebsiella pneumoniae Sequence Type 11 (ST11) and ST147 Isolates from Companion Animals

, 2017
In this study, we characterized two tigecycline-resistant Klebsiella pneumoniae isolates from dog urine samples. The isolates were genetically unrelated, belonging to sequence type 11 (ST11) and ST147, both classically related to ...
Moyano, Gabriel, Andreas Hoefer, Hoefer, Andreas, Gabriel Moyano, Escudero García-Calderón, José Antonio, Montero Serra, Natalia, Martín Espada, María Del Carmen, Martinez Ovejero, Cristina, Daniel Thomas-Lopez, Natalia Montero, Thomas-Lopez, Daniel, Jose Antonio Escudero, Bruno Gonzalez-Zorn, González Zorn, Bruno, Carmen Martin-Espada, Cristina M. Ovejero   +15 more
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Tigecycline versus INR increase; more than expected?

, 2020
Objectives: the aim of the study was to investigate the frequency of tigecycline-associated INR abnormality. Methods: Patients who were hospitalized between June and September 2016 and treated with tigecycline including therapy were extracted from ...
Akdag, Damla, Pullukcu, Husnu, Isikgoz-Tasbakan, Meltem, Sipahi, Oguz Resat, Sipahi, Hilal   +4 more
core   +1 more source

Best tigecycline dosing for treatment of infections caused by multidrug-resistant pathogens in critically ill patients with different body weights

, 2018
Mohamed M Ibrahim,1 Abdulla M Abuelmatty,2 Gehan H Mohamed,3 Mohsen A Nasr,4 Amal K Hussein,5 Mohy El Deen Ebaed,6 Hatem A Sarhan5 1Department of Clinical Pharmacy, Faculty of Pharmacy, Minia University, Minia, Egypt; 2Department of Pharmacy, Jahra ...
Sarhan HA, Ebaed MED, Mohamed GH, Nasr MA, Hussein AK, Ibrahim MM, Abuelmatty AM   +6 more
core  

Investigation of Antimicrobial Activity of Tigecycline in Methicillin Resistant Staphylococci Isolated from Hospitalized Patients in Intensive Care Units

, 2017
Aim: The aim of this study was to evaluate the in vitro antimicrobial efficacy of tigecycline in methicillin-resistant staphylococci isolated from patients hospitalized in intensive care units.
Emine Küçükateş, Nazmi Gültekin, Kucukates, Emine, Gultekin, Nazmi   +3 more
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Clinical and microbiological analysis of risk factors for breakthrough bloodstream infection during Tigecycline Therapy

Scientific Reports
Background Tigecycline is widely used to treat a variety of bacterial infections despite concerns regarding increased mortality in severe infections.
Sol Jin, So Yun Lim, Yun Woo Lee, Heungsup Sung, Mi-Na Kim, Seongman Bae, Jiwon Jung, Min Jae Kim, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Eun Hee Song, Yong Pil Chong   +13 more
doaj   +1 more source

Risk factors with the development of infection with tigecycline- and carbapenem-resistant Enterobacter cloacae

, 2019
Yuansu Jiang,* Xiaojiong Jia,* Yun Xia Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China *These authors contributed equally to this work Background: Tigecycline ...
Jiang Y, Xia Y, Jia X
core  

Exposure–response analysis of tigecycline in pharmacodynamic simulations using different size inocula of target bacteria

, 2010
This study explored tigecycline exposure-bacterial responses in pharmacodynamic simulations (in vitro kinetic model) using different inocula. One meticillin-resistant vancomycin-heteroresistant Staphylococcus aureus, one Enterococcus faecium and one ...
Sevillano, D., Giménez, M.J., González, N., Garcia-Escribano, N., Cafini. Fabio, Alou Cervera, Luis, Giménez, María José, Cafini, F., Aguilar, Lorenzo, González Hidalgo, Natalia, Garcia-Escribano, Natalia, Garcia-Rey, C., Torrico, Martha, Garcia-Rey, César, Prieto Prieto, José, Aguilar, L., Alou, L., Prieto, J, Sevillano Fernández, David, Torrico, M.   +19 more
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A promising metabolite, 9-aminominocycline, restores the sensitivity of tigecycline against tet(X4)-positive Escherichia coli

Frontiers in Microbiology
The emergence and widespread of tigecycline resistance undoubtedly poses a serious threat to public health globally. The exploration of combination therapies has become preferred antibacterial strategies to alleviate this global burden.
Feifei Sun, Feifei Sun, Lin Zhang, Xuan Ma, Tariq Ali, Yongning Wu, Lin Li   +6 more
doaj   +1 more source

The Pharmacokinetics/Pharmacodynamics and Neurotoxicity of Tigecycline Intraventricular Injection for the Treatment of Extensively Drug-Resistant Acinetobacter baumannii Intracranial Infection

Infection and Drug Resistance, 2022
Qi Huang,1 Xingwen Zhang,2 Aijun Jia,2 Qi Huang,3 Yu Jiang,4 Liangyi Xie5 1Department of Pharmacy, Hunan Provincial People’s Hospital (The first-affiliated hospital of Hunan normal university), Changsha, People’s Republic of China; 2Emergency Intensive ...
Huang Q, Zhang X, Jia A, Huang Q, Jiang Y, Xie L   +5 more
doaj  

Molecular docking result of tigecycline.

, 2014
(A) Binding pose of tigecycline in the binding site of blaOXA-1 (B) A close-up view of the binding pose of tigecycline; Protein structure is shown in surface model and the ligand is shown in stick model. (C) H-bond network with protein residues are shown.
Anand Anbarasu (539441), Madhan Sugumar (539439), Sudha Ramaiah (539442), Anand Manoharan (255198), K. M. Kumar (539440)   +4 more
core   +1 more source