Results 71 to 80 of about 26,995 (192)

In vitro activity of tigecycline against patient isolates collected during phase 3 clinical trials for hospital acquired pneumonia

Infectious Disease Reports, 2010
The in vitro activity of tigecycline was evaluated against 819 baseline pathogens isolated from 383 patients enrolled in the phase 3 clinical trial investigating the efficacy of tigecycline in hospital acquired pneumonia (HAP).
Peter J. Petersen, Margareta Tuckman, Hal Jones   +2 more
doaj   +1 more source

Do bacteria isolated from ICU patients ‘ESKAPE’ antibiotic treatment? In vitro susceptibility of the Enterobacteriaceae family to tigecycline

, 2017
Background: Enterobacteriaceae are currently causing the majority of healthcare-associated infections (HAI) andsimultaneously expressing increasing levels of antibiotic resistance.
Talaga-Ćwiertnia, Katarzyna; Department of Mycology, Chair of Microbiology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland, Krzyściak, Paweł; Department of Mycology, Chair of Microbiology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland, Bulanda, Małgorzata; Department of Epidemiology of Infections, Chair of Microbiology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland   +2 more
core   +1 more source

Nationwide Surveillance in Taiwan of the in-Vitro Activity of Tigecycline against Clinical Isolates of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae

, 2009
Tigecycline In-vitro Surveillance in Taiwan (TIST), initiated in 2006, is a nationwide surveillance programme designed to monitor longitudinally the in-vitro activity of tigecycline against commonly encountered resistant bacteria. This study compared the
LU, DANIEL C-T;CHUANG, YIN-CHING;LIU, YUNG-CHING;JANG, TSRANG-NENG;LU, PO-LIANG;CHEN, CHIH-MING;HSU, GWO-JONG;HSUEH, PO -REN, 盧進德;莊銀清;劉永慶;張藏能;盧柏樑;陳志銘;許國忠;薛博仁   +1 more
core  

Nationwide Surveillance in Taiwan of the in-Vitro Activity of Tigecycline against Clinical Isolates of Gram-Positive Cocci (Vol 32, Pg S184, 2008)

, 2011
Tigecycline In-vitro Surveillance in Taiwan (TIST), initiated in 2006, is a nationwide surveillance programme designed to monitor longitudinally the in-vitro activity of tigecycline against commonly encountered resistant bacteria in Taiwan.
曹世明;林秀真;許國忠;陳志銘;劉永慶;張藏能;盧柏樑;王立信;孔祥琪;薛博仁, TSAUR, SHYH-MING;LIN, HSIU-CHEN;HSU, GWO-JONG;CHEN, CHIH-MING;LIU, YUNG-CHING;JANG, TSRANG-NENG;LU, PO-LIANG;WANG, LIH-SHINN;KUNG, HSIANG-CHI;HSUEH, PO-REN   +1 more
core  

Tigecycline efflux as a mechanism for nonsusceptibility in acinetobacter baumannii [PDF]

, 2007
Tigecycline has an extended spectrum of in vitro antimicrobial activities, including that against multidrug-resistant Acinetobacter. After identifying bloodstream isolates of Acinetobacter with reduced susceptibilities to tigecycline, we performed a ...
Adams, Jennifer, Peleg, Anton Y., Paterson, David L.   +2 more
core   +1 more source

Carbapenem‐Resistant Gram‐Negative Bacilli in Mauritania: A Major Public Health Threat

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Carbapenem‐resistant Gram‐negative bacilli remain uncommon (4.42%) in Mauritania but are dominated by Klebsiella pneumoniae and Escherichia coli. Preserved activity of colistin, tigecycline, and amikacin highlights a narrowing therapeutic window and the urgent need for sustained surveillance and antimicrobial stewardship.
Fatimetou Ahmed Sid'Ahmed, Aminetou Mohamed Abbe, Mohamed Lemine Salem   +2 more
wiley   +1 more source

Emergence of tigecycline resistance in Escherichia coli co-producing MCR-1 and NDM-5 during tigecycline salvage treatment

, 2018
Qian Wang,1 Ping Zhang,2,3 Dongdong Zhao,2 Yan Jiang,2,3 Feng Zhao,4 Yanfei Wang,3 Xi Li,5 Xiaoxing Du,2 Yunsong Yu2,3 1Department of General Practice, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China; 2Department of ...
Jiang Y, Li X, Wang Q, Zhao F, Du X, Zhao D, Wang Y, Zhang P, Yu Y   +8 more
core  

Tigecycline therapy for carbapenem-resistant Klebsiella pneumoniae (CRKP) bacteriuria leads to tigecycline resistance

, 2014
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an increasing global threat. Here, we describe the prevalence and impact of tigecycline use in a cohort of patients with CRKP bacteriuria nested within a multicentre, prospective study. In the 21-month
Salata, R.A., Fowler, V.G., Richter, S. S., Cline, M., Kaye, K.S., Kaye, K. S., Perez, F., Kalayjian, R.C., van Duin, D., Bonomo, R.A., Cober, E.D., Kalayjian, R. C., Cober, E. D., Richter, S.S., Evans, S.R., Salata, R. A., Fowler, V. G., Evans, S. R., Bonomo, R. A.   +18 more
core   +1 more source

Investigation of Therapeutic Efficacy of Intravesical Tigecycline Administration in Rats with Cystitis Induced by Extensively Drug-Resistant (XDR), Tigecycline-Sensitive Acinetobacter baumannii Strain

Antibiotics
Background: This study aimed to evaluate the therapeutic efficacy of intravesical tigecycline administration in a rat model of cystitis induced by a tigecycline-sensitive, extensively drug-resistant (XDR) Acinetobacter baumannii strain.
Cihan Yüksel, Işıl D. Alıravcı, Murat Koşan, Sinem Esen, Sevinç Yenice Aktaş, Neslihan Kaya Terzi, Ahmet Ali Berber, Sevil Alkan, Selçuk Kaya   +8 more
doaj   +1 more source

Facing Antimicrobial Resistance and Virulence in Streptococcus agalactiae During Late Pregnancy: Evaluation of Lactobacilli as a Supportive Approach

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Integrated phenotypic, genotypic, and functional characterization of clinical Streptococcus agalactiae (Group B streptococcus, GBS) isolates from maternal carriage. Combination of selected Lactobacillus species effectively antagonize S. agalactiae by limiting bacterial growth, preserving epithelial cell viability, and reducing pathogen adhesion ...
Astri D. Tagueha, Giulia Radocchia, Daniela Scribano, Matteo Lo Scalzo, Giacinto Panella, Serena Schippa, Giovanni Gherardi, Roberta Creti, Ilaria Marani, Giovanna Alfarone, Monica Imperi, Massimiliano Marazzato, Lucia Nencioni, Paola Checconi, Dolores Limongi, Anna Teresa Palamara, Cecilia Ambrosi   +16 more
wiley   +1 more source