Results 71 to 80 of about 28,714 (188)

Emergence of Ceftazidime‐Avibactam‐Induced KPC Variants (KPC‐25/127) in Intracranial Infection and Implications for Clinical Management

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Novel KPC‐25 and first‐reported KPC‐127 sequentially evolved in one patient under CAZ‐AVI pressure, distinct mutations remodel enzyme activity to drive differential multidrug resistance. ABSTRACT The emergence of novel Klebsiella pneumoniae carbapenemase (KPC) variants contributing to clinical treatment failure poses a substantial threat to public ...
Ke Lei, Ying Tian, Chaoliang Xiong, Jing Lei, Dong Chen, Xiangni Bai, Mohd H. Abdul‐Aziz, Jiao Xie, Zeshi Liu   +8 more
wiley   +1 more source

Nationwide Surveillance in Taiwan of the in-Vitro Activity of Tigecycline against Clinical Isolates of Gram-Positive Cocci (Vol 32, Pg S184, 2008)

, 2011
Tigecycline In-vitro Surveillance in Taiwan (TIST), initiated in 2006, is a nationwide surveillance programme designed to monitor longitudinally the in-vitro activity of tigecycline against commonly encountered resistant bacteria in Taiwan.
曹世明;林秀真;許國忠;陳志銘;劉永慶;張藏能;盧柏樑;王立信;孔祥琪;薛博仁, TSAUR, SHYH-MING;LIN, HSIU-CHEN;HSU, GWO-JONG;CHEN, CHIH-MING;LIU, YUNG-CHING;JANG, TSRANG-NENG;LU, PO-LIANG;WANG, LIH-SHINN;KUNG, HSIANG-CHI;HSUEH, PO-REN   +1 more
core  

Emergence of Tigecycline and Carbapenem-Resistant Citrobacter freundii Co-Carrying tmexCD1-toprJ1, blaKPC-2, and blaNDM-1 from a Sepsis Patient

, 2023
Jinzhu Huang,* Jinxin Zhao,* Miao Yi, Yaling Yuan, Peiwen Xia, Bingxue Yang, Jiajia Liao, Zijun Dang, Yun Xia* Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ...
Liao J, Xia Y, Dang Z, Huang J, Yi M, Xia P, Yang B, Zhao J, Yuan Y   +8 more
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Detection of OXA‐23 Among Carbapenem‐Resistant Acinetobacter baumannii Isolated From Intensive Care Units of a Tertiary Care Hospital in Pakistan

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Graphical Abstract of the Experimental Workflow for CRAB Isolate Characterization. ABSTRACT Carbapenem‐resistant Acinetobacter baumannii (CRAB) has been designated a top‐priority critical pathogen by the World Health Organization, and the CDC has also classified it as a serious and immediate public health threat. The Cross‐sectional study was conducted
Hafsa Waseem, Ihsan Ullah, Shahzad Ahmad, Irfan Ali Mirza, Benish Aleem, Shazia Iqbal   +5 more
wiley   +1 more source

Effect of sub-inhibitory tigecycline (½-MIC) on AcrAB-TolC and mar/ram/sox regulatory genes in Enterobacter cloacae complex isolates

Frontiers in Cellular and Infection Microbiology
The global rise of antimicrobial resistance (AMR) in Enterobacterales, including the Enterobacter cloacae complex, is narrowing treatment options.
Lukasz Korczak, Piotr Majewski, Pawel Sacha, Dominika Chludzinska, Elzbieta Tryniszewska   +4 more
doaj   +1 more source

Green‐Synthesized Silver Nanoparticles Against Acinetobacter baumannii: A Systematic Review of Antibacterial Activity, Mechanisms of Action, Toxicity, and Antibiofilm Effects

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Schematic overview of the main antibacterial mechanisms proposed for green‐synthesized silver nanoparticles (AgNPs) against Acinetobacter baumannii. The figure summarizes the phytosynthetic pathway used to produce AgNPs (right panel) and the major reported antibacterial effects, including reactive oxygen species generation, oxidative stress, membrane ...
Shahla Shahbazi, Kimia Rafieibuzhani, Keyghobad Ghadiri, Yadollah Bahrami, Roya Chegene Lorestani, Maryam Meskini, Samira Sabzi, Mosayeb Rostamian   +7 more
wiley   +1 more source

Emergence of tigecycline resistance in Escherichia coli co-producing MCR-1 and NDM-5 during tigecycline salvage treatment

, 2018
Qian Wang,1 Ping Zhang,2,3 Dongdong Zhao,2 Yan Jiang,2,3 Feng Zhao,4 Yanfei Wang,3 Xi Li,5 Xiaoxing Du,2 Yunsong Yu2,3 1Department of General Practice, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China; 2Department of ...
Jiang Y, Li X, Wang Q, Zhao F, Du X, Zhao D, Wang Y, Zhang P, Yu Y   +8 more
core  

In-vitro activities of imipenem–colistin, imipenem–tigecycline, and tigecycline–colistin combinations against carbapenem-resistant Enterobacteriaceae*

, 2018
© 2018, © 2018 Edizioni Scientifiche per l'Informazione su Farmaci e Terapia.The aim of the study is to determine in-vitro effects of imipenem–tigecycline, imipenem–colistin and tigecycline–colistin against carbapenem-resistant Enterobacteriaceae (CRE ...
DÜNDAR, DEVRİM, Duymaz, Zehra, ER, DOĞANHAN KADİR, İrvem, Arzu, Genc, SERPİL, Kandemir, Neslisah   +5 more
core   +1 more source

Investigation of Therapeutic Efficacy of Intravesical Tigecycline Administration in Rats with Cystitis Induced by Extensively Drug-Resistant (XDR), Tigecycline-Sensitive Acinetobacter baumannii Strain

Antibiotics
Background: This study aimed to evaluate the therapeutic efficacy of intravesical tigecycline administration in a rat model of cystitis induced by a tigecycline-sensitive, extensively drug-resistant (XDR) Acinetobacter baumannii strain.
Cihan Yüksel, Işıl D. Alıravcı, Murat Koşan, Sinem Esen, Sevinç Yenice Aktaş, Neslihan Kaya Terzi, Ahmet Ali Berber, Sevil Alkan, Selçuk Kaya   +8 more
doaj   +1 more source

Tigecycline efflux as a mechanism for nonsusceptibility in acinetobacter baumannii [PDF]

, 2007
Tigecycline has an extended spectrum of in vitro antimicrobial activities, including that against multidrug-resistant Acinetobacter. After identifying bloodstream isolates of Acinetobacter with reduced susceptibilities to tigecycline, we performed a ...
Adams, Jennifer, Peleg, Anton Y., Paterson, David L.   +2 more
core   +1 more source