Results 81 to 90 of about 28,714 (188)

Bloodstream infection with pandrug-resistant Alcaligenes faecalis treated with double-dose of tigecycline

open access: yesIDCases, 2019
Introduction: Alcaligenes faecalis is a species of gram-negative, rod-shaped, aerobic bacteria commonly found in the environment. A. faecalis-associated nosocomial infections are common in hospitalized patients, but serious life threatening infections ...
Md Jahidul Hasan   +2 more
doaj   +1 more source

Evaluating Risk Factors for Clinical Failure Among Tigecycline-Treated Patients [PDF]

open access: yes
Chun-Fu Huang,1 Jia-Ling Yang,2 Yu-Chung Chuang,2,* Wang-Huei Sheng2,* 1Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan; 2Department of Internal Medicine, National Taiwan University Hospital ...
Huang CF, Sheng WH, Yang JL, Chuang YC
core  

Immunomodulatory Effects of Tigecycline in Balb/C Mice

open access: yesActa Pharmaceutica, 2018
Tigecycline is a glycylcycline antibiotic approved by the FDA for the treatment of complicated infections. Despite its effectiveness, the FDA announced a warning of increasing mortality associated with its use. There is, however, no clear explanation for
Elhayek Shada Y.   +4 more
doaj   +1 more source

Population Pharmacokinetics of Tigecycline for Critically Ill Patients Undergoing Continuous Renal Replacement Therapy [PDF]

open access: yes
Shuping Song,1,* Jieqiong Liu,2,3,* Wei Su,1 Haitao Yu,4 Binbin Feng,1 Yinshan Wu,1 Feng Guo,1 Zhenwei Yu2 1Intensive Care Unit, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2Department
Liu J   +7 more
core  

Comparison of minimal inhibitory concentrations (MICs) of tigecycline in 2011 and 2015 years against multidrug-resistance acinetobacter baumannii strains

open access: yesMedicine Science, 2017
Acinetobacter baumannii is an opportunistic pathogen that causing nosocomial infections. The microorganisms can be developed resistance to antimicrobials very quickly by different mechanisms.
Yucel Duman   +2 more
doaj   +1 more source

Population Pharmacokinetics of Tigecycline and Implications for Individualized Therapy Optimization: A Systematic Review [PDF]

open access: yes
Anran Dai,1 Feiyue Zheng,1 Jieqiong Liu,1 Qianping Chen,2 Zhou Zhou,3 Lingyan Yu,4,5 Zhenwei Yu,1,5 Yan Guan1 1Department of Pharmacy, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 2School of ...
Liu J   +7 more
core  

Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline

open access: yesNature Communications
Tigecycline is widely used for treating complicated bacterial infections for which there are no effective drugs. It inhibits bacterial protein translation by blocking the ribosomal A-site.
Xiang Li   +6 more
doaj   +1 more source

Tigecycline treatment in an infant with extensively drug-resistant Acinetobacter baumannii bacteremia

open access: yesInternational Journal of Infectious Diseases, 2017
The successful use of tigecycline in a 12-month old liver transplant recipient with extensively drug-resistant Acinetobacter baumannii bacteremia is presented.
Jiawei Zeng   +7 more
doaj   +1 more source

Efficacy of intravenous tigecycline in patients with Acinetobacter complex infections: results from 14 Phase III and Phase IV clinical trials

open access: yes, 2017
Hal Tucker, Michele Wible, Ashesh Gandhi, Alvaro QuintanaPfizer Inc, Collegeville, PA, USABackground: Acinetobacter infections, especially multidrug-resistant (MDR) Acinetobacter infections, are a global health problem.
Tucker H, Quintana A, Wible M, Gandhi A
core  

EUCAST Technical Note on tigecycline

open access: yes, 2006
Tigecycline is an injectable antibacterial agent derived from the tetracyclines and classified by the manufacturer as a glycylcycline. Tigecycline was registered by the European Medicines Agency (EMEA) in May 2006 for parenteral use in complicated ...
HRYNIEWICZ W.   +10 more
core   +1 more source

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