Results 101 to 110 of about 30,783 (205)

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

The Distribution of ESBL-Producing Enterobacteriaceae: Leicestershire UK Compared to Worldwide [PDF]

, 2019
open access ...
Reid, R., Samarasinghe, S., Varnakulasingam, Atheena   +2 more
core   +1 more source

Spectrum of Pathogens and Their Resistance Profiles in Sputum and Pus Samples: A Retrospective Study From an Eastern Hospital of Nepal

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Respiratory and soft tissue infections remain major public health challenges both globally and in Nepal, increasingly complicated by rising antimicrobial resistance (AMR). The emergence of multidrug‐resistant (MDR) and extensively drug‐resistant (XDR) pathogens has made effective treatment more difficult, underscoring the ...
Rahi Bikram Thapa, Prakash Chandra Karkee, Sabin Shrestha   +2 more
wiley   +1 more source

Heteroresistance is associated with mutations during low concentration of tigecycline therapy in multiple-resistant Klebsiella pneumoniae

Annals of Clinical Microbiology and Antimicrobials
Background Heteroresistance can lead to treatment failure and has brought a rigorous challenge to clinical laboratories for detecting them. The aim of this study was to investigate the potential for tigecycline-susceptible Klebsiella pneumoniae (K ...
Qiaoyu Zhang, Linwen Zheng, Lirong Wen, Shanshan Li, Yuli Nie, Jiansen Chen   +5 more
doaj   +1 more source

Bloodstream infections caused by Acinetobacter species with reduced susceptibility to tigecycline: clinical features and risk factors

International Journal of Infectious Diseases, 2017
Introduction: During recent decades, the rates of multidrug resistance, including resistance to carbapenems, have increased dramatically among Acinetobacter species.
Ga Eun Park, Cheol-In Kang, Min Kyeong Cha, Sun Young Cho, Hyeri Seok, Ji Hye Lee, Ji Yeon Kim, Young Eun Ha, Doo Ryeon Chung, Kyong Ran Peck, Nam Yong Lee, Jae-Hoon Song   +11 more
doaj   +1 more source

Tigecycline is efficacious in the treatment of complicated intra-abdominal infections [PDF]

, 2005
Background Empiric treatment of complicated intra-abdominal infections (cIAI) represents a clinical challenge because of the diverse bacteriology and the emergence of bacterial resistance. The efficacy and safety of tigecycline (TGC), a first-in-class,
Barauskas, Giedrius, Beuran, Mircea, Capitan-Morales, Luis-Cristobal, Dartois, Nathalie, Fomin, Peter, Gradauskas, Audrius   +5 more
core   +1 more source

Emerging Antimicrobial Resistance in Klebsiella pneumoniae: A Molecular and Antibiogram Insight From the Beef Value Chain in Bangladesh

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
A total of 132 Multidrug‐resistant Klebsiella pneumoniae was detected across the beef value chain in Bangladesh, including slaughterhouses, wet markets, and ready‐to‐eat beef outlets. Upon cultural traits, PCR, 16S rRNA sequencing, antibiogram analysis, and ARG detection revealed carbapenem resistance genes (blaIMP and blaBIC), highlighting foodborne ...
Md Sodor Uddin, Fahmida Jahan Fahim, Sohel Rana, Abdullah Al Kafi, Jobaida Khanam, Md Nazim Uddin, Md Masudur Rahman, Monira Noor, Md Mukter Hossain, Md Mahfujur Rahman, Md Bashir Uddin, Ferdaus Mohd Altaf Hossain   +11 more
wiley   +1 more source

Of Commensals and Opportunists: Genomics of Coagulase‐Negative Staphylococci During Sequential Ear and Eye Infections in a Healthy Adult

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
The genomes of coagulase‐negative staphylococci (CoNS) isolated during sequential ear and eye infections in a healthy adult are analyzed. We highlight the identification of a community‐acquired S. capitis subsp. urealyticus ST1 lineage carrying a mosaic SCCmec IV element, linking common skin commensals to multidrug‐resistant strains associated with ...
Soo Sum Lean, Chew Chieng Yeo, Zain Illyaaseen, Sargit Kaur, Yun Fong Ngeow, Stuart C. Clarke, Hien Fuh Ng   +6 more
wiley   +1 more source

The Influence of COVID‐19 on the Composition and Drug Resistance of Pleural Effusion in Shandong Province

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Our results show that the COVID‐19 pandemic has a significant impact on the detection of pathogens and drug resistance in pleural effusion in Shandong Province. ABSTRACT To analyze the composition and drug resistance changes of pleural effusion in Shandong region from 2017 to 2024, and to provide a basis for clinical empirical treatment and future ...
Wenwen Yu, Shuqing Ma, Fen Xu, Xiangmin Han, Ming Li, Yuanqi Zhu, Sufei Pan, Sujun Hou, Chunqing Ma, Fawen Deng, Shifu Wang, the SPARSS net Working Group, Ningning Ge, Fen Su, Renzhe Li, Fengyan Pei, Chunhua Han, Chengjie Guo, Mingju Hao, Bin Ji, Yan Sun, Xiulei Xue, Mingyan Sun, Yilei Li, Hongyun Cao, Hong He, Fang Wang, Zheng Zhou, Xiaoling Zan, Weiping Zhou, Xuejiao Leng, Chunzhong Dong, Xu Zheng, Shiying Sun, Wei Li, Yongjuan Ma, Jin Li, Xiao‐ying Li, Hongyan Bi, Jinjing Tian, Zhiyong Zhang, Ruifang Yang, Yulong Dai, Xuerong Sun, He Yi, Bo Yu, Fengzhi Bian, Qin Yi, Haiying Chen, Qingling Liu, Guixia Li, Jinfang Guo, Hongning Zhang, Huili Hou, Tao Chen, Zhiwei Liu, Ping Wu, Jiajia Feng, Li‐e Zhang, Junjie Dai, Jie Chen   +60 more
wiley   +1 more source

AdeABC Efflux Pump Controlled by AdeRS Two Component System Conferring Resistance to Tigecycline, Omadacycline and Eravacycline in Clinical Carbapenem Resistant Acinetobacter nosocomialis

Frontiers in Microbiology, 2020
Carbapenem-resistant Acinetobacter nosocomialis (CRAn) is a significant public health concern. Tigecycline non-susceptible CRAn (Tn-CRAn) isolates have emerged worldwide.
Yi-Tzu Lee, Yi-Tzu Lee, Hsing-Yu Chen, Ya-Sung Yang, Yu-Ching Chou, Tein-Yao Chang, Wei-Jane Hsu, I-Chieh Lin, ACTION Study Group, Jun-Ren Sun   +9 more
doaj   +1 more source