Results 91 to 100 of about 5,707,439 (181)

Plasmid-encoded tet(X) genes that confer high-level tigecycline resistance in Escherichia coli

Nature Microbiology, 2019
Tigecycline is one of the last-resort antibiotics to treat complicated infections caused by both multidrug-resistant Gram-negative and Gram-positive bacteria1.
Jian Sun, Chong Chen, Chao-yue Cui, Yan Zhang, Xiao Liu, Zehua Cui, Xiao-yu Ma, Youjun Feng, Liang-xing Fang, Xin-lei Lian, Rongmin Zhang, You-Zhi Tang, Kou-xing Zhang, Han-Mian Liu, Z. Zhuang, Shi-Dan Zhou, Jingnan Lv, Hong Du, Bin Huang, F. Yu, B. Mathema, B. Kreiswirth, Xiao-ping Liao, Liang Chen, Yahong Liu   +24 more
semanticscholar   +1 more source

In vivo Emergence of Colistin and Tigecycline Resistance in Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae During Antibiotics Treatment

Frontiers in Microbiology, 2021
Three carbapenem-resistant Klebsiella pneumoniae (CRKP; strains KP-426, KP-C76, and KP-CT77) were isolated from a patient with severe burns during the treatment of colistin and tigecycline.
Jiawei Chen, Yu Zeng, Rong Zhang, Jiachang Cai   +3 more
semanticscholar   +1 more source

Identification of novel tetracycline resistance gene tet(X14) and its co-occurrence with tet(X2) in a tigecycline-resistant and colistin-resistant Empedobacter stercoris

Emerging Microbes and Infections, 2020
Tigecycline is one of the last-resort antibiotics to treat severe infections. Recently, tigecycline resistance has sporadically emerged with an increasing trend, and Tet(X) family represents a new resistance mechanism of tigecycline.
Yingying Cheng, Yong Chen, Yang Liu, Yuqi Guo, Yanzi Zhou, Tingting Xiao, Shuntian Zhang, Hao Xu, Yunbo Chen, Tongling Shan, Yonghong Xiao, Kai Zhou   +11 more
doaj   +1 more source

Antibacterial and Antibiofilm Activity of a Chemically Characterized Cinnamomum verum Bark Methanolic Extract Against Multidrug‐Resistant Bacteria: Preliminary Antibiotic–Interaction Screening and Exploratory Molecular Docking

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The methanolic extract of Cinnamomum verum exhibited antibacterial and antibiofilm activities, enhanced the efficacy of conventional antibiotics against multidrug‐resistant bacteria, and showed favorable interactions with key bacterial targets in molecular docking analyses, supporting its potential as a natural antimicrobial adjuvant for combating ...
Hayet Edziri, Sarra Elmsehli, Assia kenich, Mabrouk Horchani, Hanen Najjaa, Naima Najah, Hasan Aljohi, Mohammad Nasser Alkhrayef, Roberta Ascrizzi, Guido Flamini, Ibrahim O. Alanazi, Mozaniel Santana de Oliveira   +11 more
wiley   +1 more source

Developmental dynamics of antibiotic resistome in aerobic biofilm microbiota treating wastewater under stepwise increasing tigecycline concentrations

Environment International, 2019
This study aimed to investigate the impact of tigecycline, the third generation tetracycline, on the antibiotic resistance development in environmental microbiota.
Zhe Tian, Ruyin Liu, Hong Zhang, Min Yang, Yu Zhang   +4 more
doaj   +1 more source

Postoperative Takotsubo Cardiomyopathy in a Young Woman: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
Timeline of the patient's clinical course. ABSTRACT Takotsubo cardiomyopathy (TCM) can occur in young adults exposed to extreme physical stress, such as surgery, sepsis, and transfusion reactions. Mechanical recovery may precede electrical normalization, with ECG abnormalities persisting despite improved left ventricular ejection fraction (LVEF). Early
Nadia Siddiq, Zoreiz Zahid Cheema, Sana Samad Khan, Aruba Arshad, Abdul Rasheed Awan, Saeedullah Shah, Muhammad Usman   +6 more
wiley   +1 more source

A widespread single amino acid mutation in AcrA reduces tigecycline susceptibility in Klebsiella pneumoniae

Microbiology Spectrum
Whole-genome sequencing of a clinical tigecycline non-susceptible Klebsiella pneumoniae strain reveals a novel T188A mutation in AcrA, raising awareness on its role in tigecycline resistance.
Yingchao Xu, Wenjia Wang, Wenya Su, Mingyu Wang, Hai Xu, Xuhua Zhang, Ling Li   +6 more
doaj   +1 more source

Aetiology and Antibiotic Susceptibility of Common Bacterial Infections in Hospitalised Patients: A 2019 Multisite Cross‐Sectional Survey in Jakarta, Indonesia

Tropical Medicine &International Health, Volume 31, Issue 9, Page 1231-1237, September 2026.
ABSTRACT Objectives To describe the aetiology and antibiotic susceptibility patterns of common bacterial infections in hospitalised patients in Jakarta, Indonesia. Methods We conducted a hospital‐wide point prevalence survey in six hospitals in 2019, capturing data from routinely ordered bacterial cultures taken before the start of antibiotic treatment.
Justin de Brabander, Erni J. Nelwan, Ralalicia Limato, Monik Alamanda, Manzilina Mudia, Enty Tjoa, Ifael Y. Mauleti, Maria Mayasari, Iman Firmansyah, T. Mannaria Jayati, Michèle van Vugt, H. Rogier van Doorn, Raph L. Hamers, Erni J. Nelwan, Ralalicia Limato, Manzilina Mudia, Monik Alamanda, Helio Guterres, Enty Enty, Y. Ifael, Maria Mayasari Mauleti, Iman Firmansyah, May Hizrani, Anis Karuniawati, Taralan Tambunan, Amin Soebandrio, Decy Subekti, Iqbal Elyazar, Mutia Rahardjani, Fitria Wulandari, Reinout van Crevel, H. Rogier van Doorn, Vu Thi Lan Huong, Nga Do Ti Thuy, Sonia Lewycka, Alex Broom, Raph L. Hamers   +36 more
wiley   +1 more source

Combination of Oral Doxycycline and Rifampin for Pan‐Drug Resistant Klebsiella pneumoniae Infection: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Pan‐drug resistant Klebsiella pneumoniae is a major therapeutic challenge, particularly when standard last‐line agents are unavailable or contraindicated. We report a 45‐year‐old man with multifocal osteomyelitis and persistent purulent wound discharge despite broad‐spectrum antibiotics, repeated debridement, and two sequential amputations ...
Ali Akbar Heydari, Sepideh Elyasi, Farshad Abedi   +2 more
wiley   +1 more source

Prevalence, Antimicrobial Resistance Profile, and Multidrug Resistance of Methicillin‐Resistant Staphylococcus aureus (MDR‐MRSA) in Clinical Isolates From Indonesian Healthcare Facility: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Methicillin‐resistant Staphylococcus aureus (MRSA) is a significant pathogen associated with hospital‐acquired infections, with its global prevalence, including in Indonesia, steadily increasing. However, comprehensive data on MRSA prevalence and antimicrobial susceptibility within Indonesian hospital settings remain ...
Muhammad Evy Prastiyanto, Afifah Khairunnisa, Shiv Kumar Sah   +2 more
wiley   +1 more source