Results 71 to 80 of about 5,707,439 (181)
Tigecycline is regarded as one of the few important last-resort antibiotics to treat complicated skin and intra-abdominal infections. Members of the genus Staphylococcus are zoonotic pathogens and pose a serious threat to public health.
Nannan Wang +5 more
doaj +1 more source
In vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii [PDF]
Sir, Acinetobacter baumannii has emerged as a leading nosocomial pathogen, particularly in intensive care units (ICUs), where several outbreaks have been described. Treatment of severe A. baumannii infection represents a difficult clinical challenge due to the propensity of this organism to acquire antimicrobial resistance, resulting in the emergence ...
A. CAPONE +4 more
openaire +4 more sources
Abstract Background Recent European Society of Clinical Microbiology and Infection and Australasian Society of Infectious Diseases Clostridioides difficile infection (CDI) management guidelines endorse the addition of intravenous tigecycline in patients who are progressing to fulminant infection.
Emma Bishop +5 more
wiley +1 more source
Tigecycline is considered one of the last-resort antimicrobials for carbapenem-resistant K. pneumoniae. Plasmid-mediated tigecycline resistance remains largely unclear.
Shijun Sun +9 more
doaj +1 more source
Convergence of plasmid-mediated Colistin and Tigecycline resistance in Klebsiella pneumoniae
Objective The co-occurrence of colistin and tigecycline resistance genes in Klebsiella pneumoniae poses a serious public health problem. This study aimed to characterize a K.
Yujie Zhao +6 more
semanticscholar +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Acinetobacter baumannii is an opportunistic pathogen that causing nosocomial infections. The microorganisms can be developed resistance to antimicrobials very quickly by different mechanisms.
Yucel Duman +2 more
doaj +1 more source
IntroductionThe tigecycline-resistant Enterobacterales have emerged as a great public concern, and the mobile tet(X) variants and tmexCD-toprJ efflux pump are mainly responsible for the spread of tigecycline resistance.
Ying Li +5 more
doaj +1 more source
Although lenvatinib is the current first‐line therapy for radioiodine‐refractory differentiated thyroid carcinoma, its use is limited by severe side effects and reduced sensitivity. Here, the authors assessed the potential of sensitizing differentiated thyroid carcinoma tumor cells with limited lenvatinib responsiveness through the administration of ...
Celina Ablinger +13 more
wiley +1 more source
The contribution of rsha mutations and efflux pumps in tigecycline resistance in abscessus [PDF]
Tigecycline is an important antibiotic in treating patients with Mycobacteroides abscessus infections. Tigecycline resistance was previously associated with dysregulated stress response induced by the abnormal interaction between the SigH and RshA ...
Aw, Kar Men
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