Results 61 to 70 of about 5,707,439 (181)

Occurrence and mechanisms of tigecycline resistance in carbapenem- and colistin-resistant Klebsiella pneumoniae in Thailand

open access: yesScientific Reports
Tigecycline has been regarded as one of the most important last-resort antibiotics for the treatment of infections caused by extensively drug-resistant (XDR) bacteria, particularly carbapenem- and colistin-resistant Klebsiella pneumoniae (C-C-RKP ...
Nachat Chirabhundhu   +6 more
semanticscholar   +1 more source

Emergence of mobile tigecycline resistance gene tet(X4)-harboring Shewanella xiamenensis in a water environment.

open access: yesJournal of Global Antimicrobial Resistance, 2022
OBJECTIVES Tigecycline resistance mediated by the mobile tigecycline-inactivating enzyme gene, tet(X), in gram-negative bacteria is an emerging concern for global public health.
Trung Duc Dao   +14 more
semanticscholar   +1 more source

Roles of Salmonella multidrug efflux pumps in tigecycline resistance [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2010
salmonella enterica strains exhibiting decreased susceptibility to tigecycline have been reported. In this study, we sought to elucidate the roles of Salmonella multidrug efflux pumps and AcrAB regulators in tigecycline resistance.we examined the involvement of multidrug efflux pumps and AcrAB regulators in resistance to tigecycline and other ...
Tsukasa, Horiyama   +3 more
openaire   +2 more sources

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki   +3 more
wiley   +1 more source

A Novel Transferable Resistance-Nodulation-Division Pump Gene Cluster, tmexCD2-toprJ2, Confers Tigecycline Resistance in Raoultella ornithinolytica

open access: yesAntimicrobial Agents and Chemotherapy, 2021
We recently identified a novel plasmid-mediated resistance-nodulation-division (RND)-type efflux pump gene cluster, tmexCD1-toprJ1, in Klebsiella pneumoniae that conferred resistance to multiple antimicrobials, including tigecycline.
Chengzhen Wang   +7 more
semanticscholar   +1 more source

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

open access: yesFood Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei   +4 more
wiley   +1 more source

Emergence and Characterization of Tigecycline Resistance Gene tet(X4) in ST609 Escherichia coli Isolates from Wastewater in Turkey

open access: yesMicrobiology spectrum, 2022
Emergence of pathogens harboring tigecycline resistance genes incurs great concerns. Wastewater is recognized as the important reservoir of antimicrobial resistance genes.
Cemil Kürekci   +6 more
semanticscholar   +1 more source

Presence of Tetracycline Resistance Determinants and Susceptibility to Tigecycline and Minocycline [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2005
ABSTRACT No relation between the presence of tetracycline resistance determinants tet (A) to tet (E) and the MICs of tigecycline was observed for Enterobacteriaceae , although tetracycline-susceptible isolates were more susceptible overall to tigecycline ...
Ad C, Fluit   +3 more
openaire   +2 more sources

Evolutionary and Epidemiological Characterization of Multidrug‐Resistant Escherichia coli Isolated From Pangolins in China

open access: yesIntegrative Zoology, EarlyView.
ABSTRACT Malayan pangolin populations have fallen to a critically endangered level, and illegal trafficking of wild pangolins is a global problem. Little is known about antimicrobial‐resistant bacteria (MDRB) harbored by pangolins, although pangolins are frequently consumed as food or used in traditional medicine. In this study, we report for the first
Yawen Wang   +8 more
wiley   +1 more source

Comprehensive Genomic Investigation of Tigecycline Resistance Gene tet(X4)-Bearing Strains Expanding among Different Settings

open access: yesMicrobiology spectrum, 2021
Tigecycline was considered the last-line drug against serious infections caused by multidrug-resistant Gram-negative bacteria. However, the plasmid-mediated tigecycline resistance gene tet(X) has been widely reported in different sources of ...
Ruichao Li   +7 more
semanticscholar   +1 more source

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