Results 241 to 250 of about 299,276 (297)

Miniature rose alleviates inflammatory bowel disease in mice by modulating gut microbiota, inhibiting TLR4, enhancing tight junction proteins, and promoting metabolism. [PDF]

Front Microbiol
Wu J, Mao X.
europepmc   +1 more source

Diagnostic Use of Testing for Novel Murine Autoantibodies for Sjögren Disease in the Rheumatology Outpatient Setting

Arthritis Care &Research, EarlyView.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr, Michael D. George, Vatinee Y. Bunya, Nora Sandorfi, Mina Massaro‐Giordano, Frederick B. Vivino   +5 more
wiley   +1 more source

SIPA1L3 via its PDZ domain inhibits the tight junction-associated AMOT-Patj to promote a malignant phenotype in NSCLC. [PDF]

Medicine (Baltimore)
Wang L, Wang BX, Zhang R, Xian SH, Wang S.   +4 more
europepmc   +1 more source

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

Arthritis Care &Research, EarlyView.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge, Gabriela Schmajuk, Sristi Sharma, Colleen P. Flanagan, Sara Faghihi‐Kashani, Ning Zhang, Mary A. Whooley   +6 more
wiley   +1 more source

Tight junction proteins in glial tumors development and progression. [PDF]

Front Cell Neurosci
Moskal J, Michalak S.
europepmc   +1 more source

AI-based prediction of drug-gene interactions modulating tight junction integrity: A deep learning framework highlighting multiple therapeutic targets. [PDF]

J Oral Biol Craniofac Res
Keskar V, Shenoy A, Desai S.
europepmc   +1 more source

Probiotic bacteria Bifidobacterium bifidum upregulation of intestinal epithelial tight junction barrier is mediated by TLR-2/TLR-6 receptor complex activation of occludin gene. [PDF]

NPJ Biofilms Microbiomes
Abdulqadir R, Al-Sadi R, Gupta Y, Rawat M, Ma T.   +4 more
europepmc   +1 more source

Kynu inhibition mitigates bile duct ischemic injury by rewiring tryptophan metabolism to restore tight junction integrity. [PDF]

Mol Med
Bao G, Zhang S, Ye Z, Luo D, Bi P, Yang B.   +5 more
europepmc   +1 more source

Gain-of-function mutations in KATP channel subunits compromise colonic tight junction integrity and epithelial homeostasis in murine models of Cantú syndrome. [PDF]

Front Med (Lausanne)
Maqoud F, Mallardi D, Orlando A, Tricarico D, Nichols CG, Antonacci M, Bianco G, Armentano R, Grassi I, Valentini AM, Russo F.   +10 more
europepmc   +1 more source

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On tight-junction structure

Cell, 1982
We have analyzed previous thin-section and freeze-fracture observations of the tight junction. We propose that the tight-junction strands represent intramembranous, cylindrical, inverted micelles. At the junctional site, the exoplasmic halves of the plasma membranes are fused into a continuous leaflet.
P, Pinto da Silva, B, Kachar
openaire   +4 more sources