Results 271 to 280 of about 130,672 (308)

Tight Junctions and Tissue Barriers

Antioxidants & Redox Signaling, 2011
The integrity and function of many vertebrate organs depend on cellular barriers that are mainly formed by intercellular protein complexes of the plasma membrane. These cell-cell contacts, tight junctions (TJs), exhibit the most apical localization in the lateral membrane; they regulate the permeability of the paracellular space between opposing ...
Ingolf E, Blasig, Reiner F, Haseloff
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Tight junctions and human diseases

Medical Electron Microscopy, 2003
Tight junctions are intercellular junctions adjacent to the apical end of the lateral membrane surface. They have two functions, the barrier (or gate) function and the fence function. The barrier function of tight junctions regulates the passage of ions, water, and various macromolecules, even of cancer cells, through paracellular spaces.
Norimasa, Sawada, Masaki, Murata, Keisuke, Kikuchi, Makoto, Osanai, Hirotoshi, Tobioka, Takashi, Kojima, Hideki, Chiba   +6 more
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Tight Junctions and Cell Polarity

Annual Review of Cell and Developmental Biology, 2006
The tight junction is an intracellular junctional structure that mediates adhesion between epithelial cells and is required for epithelial cell function. Tight junctions control paracellular permeability across epithelial cell sheets and also serve as a barrier to intramembrane diffusion of components between a cell's apical and basolateral membrane ...
Shin, K, Fogg, VC, Margolis, B
openaire   +3 more sources

Tight Junction Channels

2006
Transport across epithelia occurs through both transcellular and paracellular pathways. Transcellular movement of solutes and ions through transporters and channels is energy-dependent, directional, highly selective and regulated. Paracellular transport occurs through tight junctions, which behave like charge- and size-selective channels, but with a ...
James Melvin Anderson, Christina M. Van Itallie   +1 more
openaire   +1 more source

Human airway epithelial tight junctions

Microscopy Research and Technique, 1997
The flux of fluid, ions, macromolecules, and inflammatory cells across airway epithelium depends in part upon the integrity of its apico-lateral tight junctions. Without the correct balance of fluid and ions, the normal functioning of mucociliary clearance and the neural responsiveness of the airways cannot take place.
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Tight Junction

2012
Adamantios Arampatzis, Lida Mademli, Thomas Reilly, Mike I. Lambert, Laurent Bosquet, Jean-Paul Richalet, Thierry Busso, Bertrand Mettauer, Stéphane Gréciano, Bernard Geny, Faidon Magkos, Beat Knechtle   +11 more
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Paracellular permeability and tight junction regulation in gut health and disease

Nature Reviews Gastroenterology and Hepatology, 2023
Arie Horowitz, Sandra Chánez-Paredes
exaly  

SARS-CoV-2 crosses the blood–brain barrier accompanied with basement membrane disruption without tight junctions alteration

Signal Transduction and Targeted Therapy, 2021
Ling Zhang, Li Zhou, Linlin Bao
exaly  

Tight Junctions

2022
openaire   +1 more source

Understanding ligand-protected noble metal nanoclusters at work

Nature Reviews Materials, 2023
María Francisca Matus, Hannu Häkkinen
exaly