Results 91 to 100 of about 196,709 (295)
Tyrosine-Based Signals Regulate the Assembly of Daple⋅PARD3 Complex at Cell-Cell Junctions. [PDF]
, 2020 Polarized distribution of organelles and molecules inside a cell is vital for a range of cellular processes and its loss is frequently encountered in disease.
Choi, Julie +6 more
core
Real space first-principles derived semiempirical pseudopotentials applied to tunneling magnetoresistance [PDF]
, 2004 In this letter we present a real space density functional theory (DFT) localized basis set semi-empirical pseudopotential (SEP) approach. The method is applied to iron and magnesium oxide, where bulk SEP and local spin density approximation (LSDA) band ...
F. Aurenhammer +9 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation. [PDF]
, 2015 The blood-brain barrier (BBB) is a term used to describe the unique properties of central nervous system (CNS) blood vessels. One important BBB property is the formation of a paracellular barrier made by tight junctions (TJs) between CNS endothelial ...
Arnold, Thomas D +10 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
SPHK1/S1PR1/PPAR-α axis restores TJs between uroepithelium providing new ideas for IC/BPS treatment
Life Science AllianceThis study provides a novel therapeutic idea based on the poor limited efficacy of IC/BPS treatment options. Using urinary metabolite and tight junctions as therapeutic targets is revelatory.
Junjie Zhang +9 more
doaj +1 more source
Analysis of quantum conductance of carbon nanotube junctions by the effective mass approximation
, 1998 The electron transport through the nanotube junctions which connect the different metallic nanotubes by a pair of a pentagonal defect and a heptagonal defect is investigated by Landauer's formula and the effective mass approximation.
A. L. Mackay +30 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Josephson (001) tilt grain boundary junctions of high temperature superconductors
, 2005 We calculate the critical current $I_c$ across in-plane (001) tilt grain boundary junctions of high temperature superconductors. We solve for the electronic states corresponding to the electron-doped cuprates, two slightly different hole-doped cuprates ...
G. B. Arnold +5 more
core +1 more source