Synergistic effects of neurons and astrocytes on the differentiation of brain capillary endothelial cells in culture [PDF]
, 2003 Brain capillary endothelial cells form a functional barrier between blood and brain, based on the existence of tight junctions that limit paracellular permeability. Occludin is one of the major transmembrane proteins of tight junctions and its peripheral
Bono, E +6 more
core +1 more source
Physiology and Function of the Tight Junction [PDF]
Cold Spring Harbor Perspectives in Biology, 2009 Understanding of tight junctions has evolved from their historical perception as inert solute barriers to recognition of their physiological and biochemical complexity. Many proteins are specifically localized to tight junctions, including cytoplasmic actin-binding proteins and adhesive transmembrane proteins.
James M, Anderson +1 more
openaire +2 more sources
Snake states in graphene quantum dots in the presence of a p-n junction
, 2013 We investigate the magnetic interface states of graphene quantum dots that contain p-n junctions. Within a tight-binding approach, we consider rectangular quantum dots in the presence of a perpendicular magnetic field containing p-n, as well as p-n-p and
Farias, G. A. +3 more
core +1 more source
Propagating, evanescent, and localized states in carbon nanotube-graphene junctions [PDF]
, 2009 We study the electronic structure of the junctions between a single graphene layer and carbon nanotubes, using a tight-binding model and the continuum theory based on Dirac fermion fields.
F. Guinea +4 more
core +3 more sources
MicroRNA Regulation of Endothelial Junction Proteins and Clinical Consequence
Mediators of Inflammation, 2016 Cellular junctions play a critical role in structural connection and signal communication between cells in various tissues. Although there are structural and functional varieties, cellular junctions include tight junctions, adherens junctions, focal ...
Yugang Zhuang +3 more
doaj +1 more source
Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation [PDF]
Epithelial cells develop morphologically characteristic apical domains that are bordered by tight junctions, the apical–lateral border. Cdc42 and its effector complex Par6–atypical protein kinase c (aPKC) regulate multiple steps during epithelial ...
Balda, M.S. +7 more
core +1 more source
Epithelial cell shedding and barrier function: a matter of life and death at the small intestinal villus tip [PDF]
, 2015 The intestinal epithelium is a critical component of the gut barrier. Composed of a single layer of intestinal epithelial cells (IECs) held together by tight junctions, this delicate structure prevents the transfer of harmful microorganisms, antigens ...
A. J. M. Watson +15 more
core +4 more sources
Charge solitons and their dynamical mass in 1-D arrays of Josephson junctions
, 2010 We investigate the charge transport in one-dimensional arrays of Josephson junctions. In the interesting regime of "small charge solitons" (polarons), the charge dynamics is strongly influenced by the polaronic effects, i.e., by dressing of a Cooper pair
A. A. Odintsov +5 more
core +1 more source
SnapShot: Epithelial Tight Junctions
Cell, 2014 Tight junctions form a morphological and functional border between the apical and basolateral cell surface domains that serves as a paracellular diffusion barrier, enabling epithelial cells to separate compartments of different composition. Tight junctions also contribute to the generation and maintenance of cell polarity and regulate signaling ...
Matter, Karl, Balda, Maria S.
openaire +2 more sources
Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF [PDF]
, 2013 Several pathological processes, such as sepsis and inflammatory bowel disease (IBD), are associated with impairment of intestinal epithelial barrier. Here, we investigated the role of matrix metalloproteinase MMP13 in these diseases.
Albanese CT +15 more
core +3 more sources