Results 131 to 140 of about 26,086 (200)

Astragalus Polysaccharide Alleviates Ulcerative Colitis by Regulating the Balance of mTh17/mTreg Cells through TIGIT/CD155 Signaling

The balance between memory Th17 cells (mTh17) and memory Treg cells (mTreg) plays a key role in the pathogenesis of ulcerative colitis (UC), and TIGIT signaling is involved in the differentiation of mTh17/mTreg cells.
Jiaqi Huang, Zeyun Zhang, Zheyan Zhang, Li Huang, Duanyong Liu, Yifei Deng, Bailing Deng, Qi Wan, Qiuping Xiao, Haimei Zhao, Youbao Zhong   +10 more
core   +1 more source

The effect of TIGIT and PD1 expression on T cell function and prognosis in adult patients with acute myeloid leukemia at diagnosis

Cancer Immunology, Immunotherapy
T cell immunoreceptor with immunoglobulin and ITIM domain (TIGIT) is a recently-identified immune checkpoint molecule, and no study ever explores the prognostic significance of TIGIT on bone marrow T cells of newly-diagnosed acute myeloid leukemia (AML ...
Dai-Hong Xie, Si-Qi Li, Kai Sun, Jun Wang, Zong-Yan Shi, Ya-Zhe Wang, Yan Chang, Xiao-Ying Yuan, Hao Jiang, Qian Jiang, Ying-Jun Chang, Xiao-Jun Huang, Ya-Zhen Qin   +12 more
doaj   +1 more source

Phenotypic Landscape of Programmed Death and TIGIT/CD155/DNAM-1 Pathways in NK Cells in Ovarian Cancer. [PDF]

Biomedicines
Pawłowska-Łachut A, Skiba W, Pieniądz-Feculak P, Włodarczyk-Ciekańska K, Suszczyk D, Łyczba J, Bilska M, Kazimierczuk M, Kotarski J, Boniewska-Bernacka E, Tomaszewski J, Wertel I.   +11 more
europepmc   +1 more source

Genomic and immune profiling characterizes immune heterogeneity and a TIGIT-associated subtype in intrahepatic cholangiocarcinoma. [PDF]

Hepatol Commun
Korosteleva A, Reschke JS, Yi D, Marhenke S, Zhao J, Volk V, Reineke-Plaaß T, Peter S, Hoffmann C, Tran DDH, Gerdes C, Bathon M, Kolch W, Feuerhake F, Zhernovkov V, Saborowski A, Vogel A.   +16 more
europepmc   +1 more source

TIGIT⁺ CD4⁺ T Cell Enrichment in Colorectal Liver Metastases Is Associated with Shorter Survival. [PDF]

Cancers (Basel)
von Renesse J, Langsdorf J, Kalb E, Beer C, Digomann D, Natusch Bufe L, Aust DE, Weitz J, Seifert L, Seifert AM.   +9 more
europepmc   +1 more source

Adjuvant anti-TIGIT plus anti-PD-1 in melanoma: A necessary failure that clarifies the path forward. [PDF]

Transl Oncol
Ke Q, Zhou S.
europepmc   +1 more source

The PVR-TIGIT/CD96/CD226 axis: a novel immune checkpoint target in ovarian cancer. [PDF]

Front Immunol
Huang M, Zhang J, Huang H, Liu L, Zou Y.
europepmc   +1 more source

The Right Key, the Wrong Lock: TIGIT Checkpoint Blockade and the Road to Precision Immunotherapy. [PDF]

Pharmaceutics
Smail SW, Hamza HT, Ali MA, Yashooa RK, Nooh WA, Bapir AA, Rahman DB, Rahman MO, Haseeb HA, Maaruf NB, Majeed SO, Ezzat I, Janson C.   +12 more
europepmc   +1 more source

Integrative Omics Analysis Reveals a CD206⁺ Macrophage/Dendritic Cell-CD155-TIGIT⁺ Regulatory T Cell Axis as a Protective Immune Checkpoint Pathway in Atherosclerosis Progression. [PDF]

Barrier Immun
Shao Y, Saaoud F, Issa MB, Xu K, Lu Y, Hung SY, Liu J, Yuan B, Wei J, Wu S, Mohsin S, Zhou Z, Kosmider B, Martinez L, Vazquez-Padron R, Wang H, Yang X.   +16 more
europepmc   +1 more source

Immune checkpoint knockout screen reveals TIGIT-CD155 interaction as a significant modulator of adapter CAR-T cell function in acute myeloid leukemia. [PDF]

Oncoimmunology
Mast AS, Atar D, Ruoff L, Scheuermann S, Kristmann B, Lang P, Seitz CM, Schlegel P.   +7 more
europepmc   +1 more source