Results 21 to 30 of about 5,292 (260)

Intermittent Tiotropium Bromide for Episodic Wheezing: A Randomized Trial [PDF]

Pediatrics, 2022
BACKGROUND AND OBJECTIVES Options to treat and prevent episodic wheezing in children are scarce. Our objective was to assess the efficacy of intermittent tiotropium bromide treatment in early childhood episodic wheezing.
Anne Kotaniemi‐Syrjänen, Timo Klemola, Petri Koponen, Outi Jauhola, Henrikka Aito, Kristiina Malmström, L. Pekka Malmberg, Eero Rahiala, Seppo Sarna, Anna S. Pelkonen, Mika J. Mäkelä   +10 more
openalex   +3 more sources

Tiotropium Bromide in Chronic Obstructive Pulmonary Disease and Bronchial Asthma. [PDF]

J Clin Med Res, 2015
Inhaled bronchodilators are the mainstay of pharmacological treatment for stable chronic obstructive pulmonary disease (COPD), including β2-agonists and muscarinic antagonists. Tiotropium bromide, a long-acting antimuscarinic bronchodilator (LAMA), is a treatment choice for moderate-to-severe COPD; its efficacy and safety have been demonstrated in ...
Alvarado-Gonzalez A, Arce I.
europepmc   +5 more sources

Tiotropium bromide exerts anti-inflammatory effects during resistive breathing, an experimental model of severe airway obstruction [PDF]

International Journal of COPD, 2017
Dimitrios Toumpanakis,1,2 Konstantinos Loverdos,1,2 Vassiliki Tzouda,1,2 Vyronia Vassilakopoulou,1,2 Eleni Litsiou,1,2 Christina Magkou,3 Vassiliki Karavana,1,2 Michael Pieper,4 Theodoros Vassilakopoulos1,2 1First Critical Care Department, Pulmonary ...
Toumpanakis D, Loverdos K, Tzouda V, Vassilakopoulou V, Litsiou E, Magkou C, Karavana V, Pieper M, Vassilakopoulos T   +8 more
doaj   +2 more sources

Tiotropium Bromide Step-Up Therapy for Adults with Uncontrolled Asthma [PDF]

New England Journal of Medicine, 2010
Long-acting beta-agonist (LABA) therapy improves symptoms in patients whose asthma is poorly controlled by an inhaled glucocorticoid alone. Alternative treatments for adults with uncontrolled asthma are needed.In a three-way, double-blind, triple-dummy crossover trial involving 210 patients with asthma, we evaluated the addition of tiotropium bromide ...
Stanley J. Szefler, Robert F. Lemanske, William J. Calhoun, Timothy J. Craig, Michael J. Walter, Reuben M. Cherniack, Michael E. Wechsler, Joe W. Ramsdell, Susan J. Kunselman, Nizar N. Jarjour, Rodolfo M. Pascual, Stephen I. Wasserman, E. Rand Sutherland, Linda Engle, Christine A. Sorkness, Vernon M. Chinchilli, Homer A. Boushey, Njira L Lugogo, Mario Castro, Loren C. Denlinger, Deborah A. Meyers, Monica Kraft, Richard J. Martin, Nikolina Icitovic, Stephen P. Peters, Elliot Israel, Eugene R. Bleecker, Stephen C. Lazarus, John V. Fahy, Shamsah Kazani, Bill T. Ameredes, Emily DiMango, Wendy C. Moore   +32 more
openaire   +5 more sources

Improvement in 24-hour bronchodilation and symptom control with aclidinium bromide versus tiotropium and placebo in symptomatic patients with COPD: post hoc analysis of a Phase IIIb study

International Journal of COPD, 2017
Jutta Beier,1 Robert Mroz,2,3 Anne-Marie Kirsten,4 Ferran Chuecos,5 Esther Garcia Gil5 1insaf Respiratory Research Institute, Wiesbaden, Germany; 2Centrum Medycyny Oddechowej, 3Medical University of Białystok, Białystok, Poland; 4Pulmonary Research ...
Beier J, Mroz R, Kirsten AM, Chuecos F, Garcia Gil E   +4 more
doaj   +3 more sources

DEVELOPMENT AND VALIDATION OF UV-SPECTROSCOPIC METHOD FOR ESTIMATION OF TIOTROPIUM BROMIDE IN API AND PHARMACEUTICAL DOSAGE FORM [PDF]

, 2020
Objective: The current work intended towards the developed and validated UV spectrophotometric method for the estimation of Tiotropium Bromide in API and pharmaceutical formulation. Methods: The UV spectrum of tiotropium bromide in methanol shows maximum
ANJALI P. KOKANE, BHAGYASHRI S. SHINDE, M. S. KALSHETTI   +2 more
openalex   +4 more sources

¹H-NMR-based metabolic profiling of healthy individuals and high-resolution CT-classified phenotypes of COPD with treatment of tiotropium bromide. [PDF]

Int J Chron Obstruct Pulmon Dis, 2018
Tan LC, Yang WJ, Fu WP, Su P, Shu JK, Dai LM.   +5 more
europepmc   +3 more sources

LUNG FUNCTION IMPROVEMENTS WITH TIOTROPIUM BROMIDE IN CONSTRICTIVE BRONCHIOLITIS [PDF]

Chest, 2005
Ronaldo Adib Kairalla, Marcelo Jorge Jacó Rocha, Carlos Roberto Ribeiro de Carvalho   +2 more
openalex   +3 more sources

Effect of different doses of Budesonide combined with Tiotropium bromide inhalation on elderly patients with chronic obstructive pulmonary disease. [PDF]

Pak J Med Sci
Yu J, Ni J, Chen X, Fang Y, Fu S.
europepmc   +3 more sources

Quantitative Analysis of Muscarinic Antagonist Atropine and Tiotropium in Microvolume Plasma Using Liquid Chromatography-Mass Spectrometry: Application for Pharmacokinetic Studies. [PDF]

J Anal Methods Chem
Despite the availability of current resources, the development of medical countermeasures remains crucial in combatting the threat posed by chemical warfare agents, such as organophosphorus compounds (OPs), which are toxic nerve agents requiring rapid medical intervention.
Trancart M, Penot M, Meesemaecker G, Boffy R, Hanak AS, Calas AG, Taudon N.   +6 more
europepmc   +2 more sources