Results 81 to 90 of about 4,977 (213)

The Real‐World Analysis of Adverse Events With Two Types of Single‐Inhaler Triple Therapy: A VigiAccess Database Study

open access: yesJournal of Clinical Pharmacy and Therapeutics, Volume 2025, Issue 1, 2025.
Background The advent of single‐inhaler triple therapies (SITTs), including fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) and beclomethasone dipropionate/formoterol fumarate/glycopyrronium bromide (BDP/FOR/GLY), has expanded treatment options for chronic obstructive pulmonary disease (COPD).
Baiquan Zhang   +3 more
wiley   +1 more source

Cost-effectiveness of tiotropium versus omalizumab for uncontrolled allergic asthma in US

open access: yesCost Effectiveness and Resource Allocation, 2018
Background A significant minority of asthma patients remain uncontrolled despite the use of inhaled corticosteroids (ICS) and long-acting beta-agonists (LABA).
Zafar Zafari   +3 more
doaj   +1 more source

Risk factors for COPD exacerbations in inhaled medication users: the COPDGene study biannual longitudinal follow-up prospective cohort. [PDF]

open access: yes, 2016
BackgroundDespite inhaled medications that decrease exacerbation risk, some COPD patients experience frequent exacerbations. We determined prospective risk factors for exacerbations among subjects in the COPDGene Study taking inhaled medications ...
,   +8 more
core   +4 more sources

Drugs Used in the Treatment of Viral Infections for the Prevention of Airway Remodeling in Asthma

open access: yesMediators of Inflammation, Volume 2025, Issue 1, 2025.
One of the main causes of the exacerbation of chronic airway inflammatory diseases is respiratory virus infections. The most prevalent viruses that can infect humans multiple times a year are rhinovirus (RV) and respiratory syncytial virus (RSV). Because remodeling factors like matrix metalloproteinases (MMPs), which are released by infiltrating ...
Joanna Wieczfinska   +2 more
wiley   +1 more source

Efficacy and safety of aclidinium bromide/formoterol fumarate fixed-dose combinations compared with individual components and placebo in patients with COPD (ACLIFORM-COPD): a multicentre, randomised study [PDF]

open access: yes, 2014
Background Aclidinium/formoterol is a twice-daily (BID) fixed-dose combination (FDC) in development for chronic obstructive pulmonary disease (COPD).
Dave Singh   +8 more
core   +1 more source

Tools for clinical pharmacists to identify medications that can cause drug‐induced cognitive impairment: A systematic review

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 7, Issue 12, Page 1207-1227, December 2024.
Abstract Cognitive impairment affects around 19% of community‐dwelling older adults in the United States. Pharmacists can play a significant role in identifying and deprescribing cognitive‐impairing medications through cognitive‐focused medication reviews or as part of comprehensive medication management.
Jacob Stanton   +4 more
wiley   +1 more source

Efficacy and Safety of Aclidinium Bromide Compared with Placebo and Tiotropium in Patients with Moderate-to-Severe Chronic Obstructive Pulmonary Disease: Results from a 6-week, Randomized, Controlled Phase Iiib Study

open access: yesCOPD, 2013
Background: This randomized, double-blind, Phase IIIb study evaluated the 24-hour bronchodilatory efficacy of aclidinium bromide versus placebo and tiotropium in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD).
Jutta Beier   +6 more
doaj   +1 more source

What can we learn about COPD from impulse oscillometry? [PDF]

open access: yes, 2018
Impulse oscillometry (IOS) is the most commonly used type of forced oscillation technique in clinical practice, although relatively little is known about its application in COPD.
Jabbal, Sunny, Lipworth, Brian J.
core   +2 more sources

New potent muscarinic receptor ligands bearing the 1,4‐dioxane nucleus: Investigation on the nature of the substituent in position 2

open access: yesArchiv der Pharmazie, Volume 357, Issue 10, October 2024.
The role of different substituents in position 2 of 6,6‐diphenyl‐1,4‐dioxane muscarinic receptor ligands in the affinity for the five muscarinic acetylcholine receptor (mAChR) subtypes was studied. The tertiary amine 9 and its eutomer (S)‐(–)‐9 showed picomolar affinity and biphasic curves for all mAChRs.
Gianfabio Giorgioni   +10 more
wiley   +1 more source

A controlled study of community-based exercise training in patients with moderate COPD. [PDF]

open access: yes, 2014
BackgroundThe effectiveness of clinic-based pulmonary rehabilitation in advanced COPD is well established, but few data exist for less severe patients treated in alternative settings.
Abrazado, Marlon   +5 more
core   +2 more sources

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