Epicardial Adipose Tissue Segmentation from CT Images with A Semi-3D Neural Network [PDF]
2021 International Symposium ELMAR, 2021, pp. 87-90, 2022 Epicardial adipose tissue is a type of adipose tissue located between the heart wall and a protective layer around the heart called the pericardium. The volume and thickness of epicardial adipose tissue are linked to various cardiovascular diseases. It is shown to be an independent cardiovascular disease risk factor.
arxiv +1 more source
Post-transcriptional regulation across human tissues [PDF]
PLoS Comput Biol 13(5): e1005535 (2017), 2015 Transcriptional and post-transcriptional regulation shape tissue-type-specific proteomes, but their relative contributions remain contested. Estimates of the factors determining protein levels in human tissues do not distinguish between (i) the factors determining the variability between the abundances of different proteins, i.e., mean-level ...
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Explicit physics-informed neural networks for non-linear upscaling closure: the case of transport in tissues [PDF]
, 2021 In this work, we use a combination of formal upscaling and data-driven machine learning for explicitly closing a nonlinear transport and reaction process in a multiscale tissue. The classical effectiveness factor model is used to formulate the macroscale reaction kinetics. We train a multilayer perceptron network using training data generated by direct
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An Empirical Bayes Regression for Multi-tissue eQTL Data Analysis [PDF]
arXiv, 2022 The Genotype-Tissue Expression (GTEx) project collects samples from multiple human tissues to study the relationship between genetic variation or single nucleotide polymorphisms (SNPs) and gene expression in each tissue. However, most existing eQTL analyses only focus on single tissue information.
arxiv
Temperature Effects on Brain Tissue in Compression [PDF]
Journal of the Mechanical Behavior of Biomedical Materials, 14
(2012) 113-118, 2013 Extensive research has been carried out for at least 50 years to understand the mechanical properties of brain tissue in order to understand the mechanisms of traumatic brain injury (TBI). The observed large variability in experimental results may be due to the inhomogeneous nature of brain tissue and to the broad range of test conditions.
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Multi-Compartmental Biomaterial Scaffolds for Patterning Neural Tissue Organoids in Models of Neurodevelopment and Tissue Regeneration [PDF]
J. Tissue Engineering 2016; 7:1-8, 2016 Biomaterials are becoming an essential tool in the study and application of stem cell research. Various types of biomaterials enable three-dimensional (3D) culture of stem cells, and, more recently, also enable high-resolution patterning and organization of multicellular architectures.
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Oxygen depletion hypothesis remains controversial: a mathematical model of oxygen depletion during FLASH radiation [PDF]
Radiation Research . 2022. 197(2):175-183, 2020 Background: Experiments have reported low normal tissue toxicities during FLASH radiation, but the mechanism has not been elaborated. Several hypotheses have been proposed to explain the mechanism. The oxygen depletion hypothesis has been introduced and mostly studied qualitatively.
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Sparse multi-view matrix factorisation: a multivariate approach to multiple tissue comparisons [PDF]
, 2015 Gene expression levels in a population vary extensively across tissues. Such heterogeneity is caused by genetic variability and environmental factors, and is expected to be linked to disease development. The abundance of experimental data now enables the identification of features of gene expression profiles that are shared across tissues, and those ...
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An Eulerian nonlinear elastic model for compressible and fluidic tissue with radially symmetric growth [PDF]
arXiv, 2021 Cell proliferation, apoptosis, and myosin-dependent contraction can generate elastic stress and strain in living tissues, which may be dissipated by internal rearrangement through cell topological transition and cytoskeletal reorganization. Moreover, cells and tissues can change their sizes in response to mechanical cues.
arxiv
Tissue failure propagation as mediated by circulatory flow [PDF]
, 2020 Aging is driven by subcellular processes that are relatively well-understood. However the qualitative mechanisms and quantitative dynamics of how these micro-level failures cascade to a macro-level catastrophe in a tissue or organs remain largely unexplored.
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