Results 31 to 40 of about 17,692,743 (361)
Cells release diverse types of vesicles constitutively or in response to proliferation, injury, inflammation, or stress. Extracellular vesicles (EVs) are crucial in intercellular communication, and there is emerging evidence for their roles in ...
C. Tripisciano+6 more
semanticscholar +1 more source
Tissue factor and cancer [PDF]
The hemostatic system is involved in multiple interactions with transformed cells that progress from a dormant, non-vascularized tumor to highly metastatic phenotypes. Oncogenic transformations up regulate not only the initiator of the coagulation cascade, tissue factor (TF), but also induce other molecules that are required for TF's direct cell ...
openaire +3 more sources
Decryption of tissue factor [PDF]
Tissue factor (TF) is a transmembrane protein which, in complex with factor (F)VIIa, initiates blood coagulation. Numerous studies have determined TF epitopes and individual amino acids which play an important role in the TF/FVIIa complex formation and its activity towards natural substrates.
Saulius Butenas, Jolanta Krudysz-Amblo
openaire +2 more sources
Heparanase—A Link between Coagulation, Angiogenesis, and Cancer
Heparanase that was cloned from and is abundant in the placenta is implicated in cell invasion, tumor metastasis, and angiogenesis. Recently we have demonstrated that heparanase may also affect the hemostatic system in a non-enzymatic manner.
Yona Nadir, Benjamin Brenner
doaj +1 more source
Potential biochemical markers of chronic bronchitis
The review systematizes modern data on the biochemical markers that can clarify the nature and the course of chronic bronchitis. The article describes markers associated with bronchopulmonary pathology, such as tumor necrosis factor alpha (TNFα ...
E. A. Kurtukov, Yu. I. Ragino
doaj +1 more source
Tissue Factor Encryption [PDF]
Tissue factor (TF) encryption is the post-translational suppression of TF procoagulant activity (PCA) on the cell surface. There is emerging evidence of encrypted TF in normal blood associated with monocytes and platelets. Expression of this latent TF PCA during the propagation phase of blood coagulation may contribute to hemostasis.
openaire +3 more sources
Introduction: Coagulation and fibrinolysis remain sparsely addressed with regards to acute respiratory distress syndrome (ARDS). We hypothesized that ARDS development might be associated with changes in plasma coagulation and fibrinolysis. Our aim was to
Agnese Ozolina+12 more
doaj +1 more source
Patients suffering from chronic kidney disease (CKD) are at a 20-fold higher risk of dying due to cardiovascular diseases (CVDs), primarily thrombosis following vascular injury. CKD is connected with retention of uremic toxins, especially indoxyl sulfate
Malgorzata Karbowska+9 more
doaj +1 more source
Local hemostasis disorders underlying endometric pathology
Introduction. Hemostasis is an equilibrium system that performs 2 bidirectional tasks: on the one hand, it prevents bleeding development, whereas on the other hand, it counters thrombogenesis.
E. Iu. Iupatov+6 more
doaj +1 more source
Background Vascular diseases are highly associated with inflammation and thrombosis. Elucidating links between these two processes may provide a clearer understanding of these diseases, allowing for the design of more effective treatments. The activation
Christopher T. Freda+3 more
doaj +1 more source