Results 31 to 40 of about 3,935,952 (212)

The 5' untranslated region of the I factor, a long interspersed nuclear element-like retrotransposon of Drosophila melanogaster, contains an internal promoter and sequences that regulate expression [PDF]

, 1993
The I-R system of hybrid dysgenesis in Drosophila melanogaster is controlled by a long interspersed nuclear element-like retroposon, the I factor.
BUCHETON, A, FINNEGAN, D J, Finnegan, David, MCLEAN, C   +3 more
core   +1 more source

Vascular miR‐181b controls tissue factor‐dependent thrombogenicity and inflammation in type 2 diabetes [PDF]

, 2020
BACKGROUND: Diabetes mellitus is characterized by chronic vascular inflammation leading to pathological expression of the thrombogenic full length (fl) tissue factor (TF) and its isoform alternatively-spliced (as) TF. Blood-borne TF promotes factor (
Chakraborty, Aritra, Dörner, Andrea, Friebel, Julian, Krueger, Andreas, Landmesser, Ulf, Rauch, Ursula, Ruf, Wolfram, Saffarzadeh, Mona, Stratmann, Bernd, Ta Bao, Loc, Tabaraie, Termeh, Tschoepe, Diethelm, Winter, Samantha J., Witkowski, Marco, Witkowski, Mario   +14 more
core   +1 more source

Activation of Coagulation and Fibrinolysis in Acute Respiratory Distress Syndrome: a Prospective Pilot Study

Frontiers in Medicine, 2016
Introduction: Coagulation and fibrinolysis remain sparsely addressed with regards to acute respiratory distress syndrome (ARDS). We hypothesized that ARDS development might be associated with changes in plasma coagulation and fibrinolysis. Our aim was to
Agnese Ozolina, Agnese Ozolina, Marina Sarkele, Marina Sarkele, Olegs Sabelnikovs, Olegs Sabelnikovs, Andrejs Skesters, Inta Jaunalksne, Jelena Serova, Talis Ievins, Lars Jakob Bjertnæs, Indulis Vanags, Indulis Vanags   +12 more
doaj   +1 more source

Conformational Plasticity-Rigidity Axis of the Coagulation Factor VII Zymogen Elucidated by Atomistic Simulations of the N-Terminally Truncated Factor VIIa Protease Domain

Biomolecules, 2021
The vast majority of coagulation factor VII (FVII), a trypsin-like protease, circulates as the inactive zymogen. Activated FVII (FVIIa) is formed upon proteolytic activation of FVII, where it remains in a zymogen-like state and it is fully activated only
Jesper J. Madsen, Ole H. Olsen
doaj   +1 more source

Porcine bone scaffolds adsorb growth factors secreted by MSCs and improve bone tissue repair [PDF]

, 2017
An ideal tissue-engineered bone graft should have both excellent pro-osteogenesis and pro-angiogenesis properties to rapidly realize the bone regeneration in vivo . To meet this goal, in this work a porcine bone scaffold was successfully used as a Trojan
Bressan, Eriberto, Ferroni, Letizia, Gardin, Chiara, Mijiritsky, Eitan, Piattelli, Adriano, Zanette, Gastone, Zavan, Barbara   +6 more
core   +2 more sources

Indoxyl Sulfate Promotes Arterial Thrombosis in Rat Model via Increased Levels of Complex TF/VII, PAI-1, Platelet Activation as Well as Decreased Contents of SIRT1 and SIRT3

Frontiers in Physiology, 2018
Patients suffering from chronic kidney disease (CKD) are at a 20-fold higher risk of dying due to cardiovascular diseases (CVDs), primarily thrombosis following vascular injury. CKD is connected with retention of uremic toxins, especially indoxyl sulfate
Malgorzata Karbowska, Tomasz W. Kaminski, Beata Znorko, Tomasz Domaniewski, Tomasz Misztal, Tomasz Rusak, Anna Pryczynicz, Katarzyna Guzinska-Ustymowicz, Krystyna Pawlak, Dariusz Pawlak   +9 more
doaj   +1 more source

Tissue factor potentiates adherence of breast cancer cells to human umbilical vein endothelial cells under static and flow conditions

Cell Adhesion & Migration, 2021
Tissue factor (TF) has been extensively studied for tumor metastasis, but its role in mediating cancer cell adhesion to vasculature remains unknown. This study aimed to measure the ability of TF to mediate the adhesion of breast cancer cells to human ...
Yanling Jin, Wei Liu, Fengxia Wang, Min Wang, Kai Xu, Aijun Yang, Chenyu Wang, Lihan Zhang, Fangfang Zhang, Min Li   +9 more
doaj   +1 more source

Exploring the Mechanism of Chuanxiong Rhizoma against Thrombosis Based on Network Pharmacology, Molecular Docking and Experimental Verification

Molecules, 2023
Chuanxiong rhizoma (CX) has been utilized for centuries as a traditional herb to treat blood stasis syndromes. However, the pharmacological mechanisms are still not completely revealed.
Shasha He, Xuhua He, Shujuan Pan, Wenwen Jiang   +3 more
doaj   +1 more source

Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-beta and Runx2 in bone is required for hearing [PDF]

, 2010
Publisher version: http://www.nature.com/embor/journal/v11/n10/full/embor2010135.htmlDA - 20100917 IS - 1469-3178 (Electronic) IS - 1469-221X (Linking) LA - ENG PT - JOURNAL ARTICLEDA - 20100917 IS - 1469-3178 (Electronic) IS - 1469-221X (Linking) LA ...
Alexandra E Porter, Anil Lalwani, Carol G Chen, Currey JD, Delia S Brauer, Emily N Chin, Filvaroff E, Grayson W Marshall, Guive Balooch, Higashi K, Jacob Johnson, Jolie L Chang, Kristin Butcher, Lawrence Lustig, Mary Beth Humphrey, Omar Akil, Richard A Schneider, Rik Derynck, Robert O Ritchie, Sally J Marshall, Sorensen MS, Tamara Alliston   +21 more
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Tissue Factor [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2009
Series Editor: Nigel Mackman Mark B. Taubman ATVB In Focus Tissue Factor: Past, Present, and Future Articles in this series: •Mackman N. Tissue factor: past, present, and future. Arterioscler Thromb Vasc Biol 2009;29:1986–1988. •Butenas S, Orfeo T, Mann KG. Tissue factor in coagulation: which? where? when?
Nigel, Mackman, Mark, Taubman
openaire   +2 more sources