Results 21 to 30 of about 174,743 (266)
Tissue inhibitor of metalloproteinase-1 predicts adiposity in humans [PDF]
Objective: Tissue inhibitor of metalloproteinase (TIMP)-1 is upregulated in fat of obese rodents and promotes adipose tissue development in these animals. However, it is unclear whether TIMP-1 independently predicts adiposity in humans and whether serum levels are increased in s.c. and visceral obesity. Design: Twenty-four lean, 16 s.c.
Susan, Kralisch +6 more
openaire +2 more sources
Airway remodeling is a significant factor in the progression of respiratory failure in bronchial asthma (BA). Obesity can contribute to inflammation, and consequently – airway remodeling, by increased production of matrix proteinase (MMP).
V. V. Kachkovska, L. N. Prystupa
doaj +1 more source
Hypertension (HTN) is a leading risk factor for cardiovascular (CV) disease. Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are thought to be actively involved in the remodeling of the CV extracellular matrix (ECM) during ...
Krasimir Kostov, Alexander Blazhev
doaj +1 more source
Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in diagnosis of pleural effusion of malignant origin [PDF]
OBJECTIVES: The aim of the present study was to evaluate the diagnostic accuracy of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in differentiating benign from malignant exudative pleural effusions.
D'Angelo, L. +7 more
core +1 more source
Matrix metalloproteinases-9 and tissue inhibitor of matrix metalloproteinases-1 in sarcoidosis patients [PDF]
Matrix metaloproteinases (MMPs) and their specific inhibitors - tissue inhibitors of matrix metalloproteinases (TIMPs) play an important role in pulmonary extracellular matrix destruction. Sarcoidosis is an inflammatory disease affecting multiple organs.
Ivanišević Jasmina +6 more
doaj +1 more source
Aims. In order to study the levels of matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, intracardiac hemodynamics, frequency of acute cardiac aneurysm development in patients with Q-wave myocardial infarction after thrombolysis, 74 ...
V. D. Syvolap , S. M. Kyselov
doaj +1 more source
Integrin α2β1 Expression Regulates Matrix Metalloproteinase-1-Dependent Bronchial Epithelial Repair in Pulmonary Tuberculosis. [PDF]
Pulmonary tuberculosis (TB) is caused by inhalation of Mycobacterium tuberculosis, which damages the bronchial epithelial barrier to establish local infection.
Akif A. Khawaja +8 more
core +6 more sources
Objective. Aldosterone receptor blockade regulate activity of matrix metalloproteinase system, increase survival in postinfarction period. Methods and results.
S. M. Kyselov
doaj +1 more source
Cell surface engineering of renal cell carcinoma with glycosylphosphatidylinositol-anchored TIMP-1 blocks TGF-beta 1 activation and reduces regulatory ID gene expression [PDF]
Tissue inhibitor of metalloproteinase 1 (TIMP-1) controls matrix metalloproteinase activity through 1:1 stoichiometric binding. Human TIMP-1 fused to a glycosylphosphatidylinositol (GPI) anchor (TIMP-1-GPI) shifts the activity of TIMP-1 from the ...
Djafarzadeh, Roghieh +5 more
core +2 more sources
Aim. Matrix metalloproteinases play a key role in adaptive postinfarction remodeling of the heart. In order to study the influence of anticoagulation therapy on the state of matrix metalloproteinases and their inhibitors, the incidence of post-infarction
S. M. Kyselov
doaj +1 more source

