Results 11 to 20 of about 66,322 (262)
Kidney & Blood Pressure Research, 2021 Introduction: Under physiological conditions, the myocardial extracellular matrix (ECM) is maintained by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). However, changes in the balance between MMPs and TIMPs can lead
Małgorzata Kobusiak-Prokopowicz +4 more
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Matrix metalloproteinases-9 and tissue inhibitor of matrix metalloproteinases-1 in sarcoidosis patients [PDF]
Arhiv za farmaciju, 2017 Matrix metaloproteinases (MMPs) and their specific inhibitors - tissue inhibitors of matrix metalloproteinases (TIMPs) play an important role in pulmonary extracellular matrix destruction. Sarcoidosis is an inflammatory disease affecting multiple organs.
Ivanišević Jasmina +6 more
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Engineered Sarafotoxins as Tissue Inhibitor of Metalloproteinases-like Matrix Metalloproteinase Inhibitors [PDF]
Journal of Biological Chemistry, 2007 The sarafotoxins and endothelins are approximately 25-residue peptides that spontaneously fold into a defined tertiary structure with specific pairing of four cysteines into two disulfide bonds. Their structures show an interesting topological similarity to the core of the metalloproteinase interaction sites of the tissue inhibitors of ...
Janelle L, Lauer-Fields +5 more
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Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases [PDF]
Circulation Research, 2003 Matrix metalloproteinases (MMPs), also designated matrixins, hydrolyze components of the extracellular matrix. These proteinases play a central role in many biological processes, such as embryogenesis, normal tissue remodeling, wound healing, and angiogenesis, and in diseases such as atheroma, arthritis, cancer, and tissue ulceration.
Visse, R, Nagase, H
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Haematologica, 2010 Background Inherited defects decreasing function of the Fas death receptor cause autoimmune lymphoproliferative syndrome and its variant Dianzani’s autoimmune lymphoproliferative disease.
Elena Boggio +8 more
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Вестник хирургии имени И.И. Грекова, 2022 The OBJECTIVE was to study the state of serum matrix metalloproteinase and their prognostic value in closed spleen injuries in the immediate postoperative period.METHODS AND MATERIALS.
V. V. Masljakov +3 more
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Tissue inhibitors of metalloproteinases [PDF]
Genome Biology, 2011 Orchestration of the growth and remodeling of tissues and responses of cells to their extracellular environment is mediated by metalloproteinases of the Metzincin clan. This group of proteins comprises several families of endopeptidases in which a zinc atom is liganded at the catalytic site to three histidine residues and an invariant methionine ...
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The role of matrix metalloproteinases in early and late gonarthrosis manifestations
Russian Open Medical Journal, 2020 The aim of this research was to study the specifics of the matrix metallopeptidase system in early and late gonarthrosis (GA) manifestations. Material and Methods — 37 patients of the main group (0-I stages of GA), 30 patients of the comparison group ...
Ekaterina V. Gladkova
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Tissue Inhibitor of Metalloproteinase-1: Actions beyond Matrix Metalloproteinase Inhibition [PDF]
Cardiology, 2015 Matrix metalloproteinases (MMPs) are a family of zinc-dependent enzymes, which include 25 current members. MMPs degrade structural components of extracellular matrix and process bioactive molecules including cytokines, chemokines, and growth factors [1].
Merry L. Lindsey +2 more
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Annals of Agricultural and Environmental Medicine, 2016 Introduction The prevalence of endometriosis among reproductive age women is 7–17%; however, these figures reach 20–50% in patients suffering from infertility. Matrix metalloproteinases (MMPs) activity is thought to be particularly essential in the early
Krzysztof Szymanowski +3 more
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