Results 51 to 60 of about 17,677,818 (279)
Tissue-resident memory-like ILCs: innate counterparts of TRM cells
Protein & Cell, 2019 Innate lymphoid cells (ILCs) are defined as lymphocytes that lack RAG recombinase and do not express diverse antigen receptors; however, recent studies have revealed the adaptive features of ILCs. Mouse cytomegalovirus (MCMV)- and cytokine-induced memory
Xianwei Wang, Zhigang Tian, Hui Peng
doaj +1 more source
, 2022 Supplementary Figure from Dopamine Signaling Promotes Tissue-Resident Memory Differentiation of CD8+ T Cells and Antitumor ...
Yingtong Lin (2814325) +13 more
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IFN-γ–dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit allergic contact dermatitis [PDF]
, 2023 BACKGROUND: Elicitation of allergic contact dermatitis (ACD), an inflammatory type 4 hypersensitivity disease, induces skin infiltration by polyclonal effector CD8 αβ T cells and precursors of tissue-resident memory T (TRM) cells.
Llorian, Miriam +35 more
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Formation of Tissue-Resident CD8+ T-Cell Memory [PDF]
Cold Spring Harbor Perspectives in Biology, 2021 Resident memory CD8+ T (Trm) cells permanently reside in nonlymphoid tissues where they act as a first line of defense against recurrent pathogens. How and when antigen-inexperienced CD8+ T cells differentiate into Trm has been a topic of major interest, as knowledge on how to steer this process may be exploited in the development of vaccines and ...
Feline E, Dijkgraaf +2 more
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Tissue-resident memory T cells orchestrate tumour-immune equilibrium
Cell Stress, 2019 The immune system can prevent tumour development by engaging in a process termed cancer immunosurveillance, during which immune cells such as T cells restrict tumour growth either by completely eradicating cancer cells in a process of ‘elimination’ or by
Simone L. Park +3 more
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Development and function of tissue-resident memory CD8+ T cells [PDF]
, 2023 Tissue-resident memory (TRM) CD8+ T cells permanently reside within non-lymphoid tissues where they provide a first-line of defense against invading pathogens.
Hobbs, Samuel
core +1 more source
Tissue-Resident Memory T Cell: Ontogenetic Cellular Mechanism and Clinical Translation [PDF]
, 2023 Mounting evidence has indicated the essential role of tissue-resident memory T (TRM) cells for frontline protection against viral infection and for cancer immune surveillance (Mueller SN, Mackay LK.
Zhou, Runhong +5 more
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Tissue-resident memory T cells in tumor immunity and immunotherapy
Journal of Experimental Medicine, 2021 Tissue-resident memory T cells (TRM) represent a heterogeneous T cell population with the functionality of both effector and memory T cells. TRM express residence gene signatures. This feature allows them to traffic to, reside in, and potentially patrol peripheral tissues, thereby enforcing an efficient long-term immune-protective role.
Karolina Okła +2 more
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Assessing the generation of tissue resident memory T cells by vaccines
Nature Reviews Immunology, 2023 Vaccines have been a hugely successful public health intervention, virtually eliminating many once common diseases of childhood. However, they have had less success in controlling endemic pathogens including Mycobacterium tuberculosis, herpesviruses and HIV.
Elizabeth Rotrosen, Thomas S. Kupper
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source