Results 41 to 50 of about 17,677,818 (279)

Non-hematopoietic cells in lymph nodes drive memory CD8 T cell inflation during murine cytomegalovirus infection. [PDF]

, 2011
During human and murine cytomegalovirus (MCMV) infection an exceptionally large virus-specific CD8 T cell pool is maintained in the periphery lifelong.
Torti, Nicole, Oxenius, Annette, Walton, Senta M., Walton Senta M., Rülicke Thomas, Senta M Walton, Torti Nicole, Oxenius Annette, Brocker, Thomas, Senta M. Walton, Rülicke, Thomas, Nicole Torti, Brocker Thomas, Thomas Brocker, Thomas Rülicke, Annette Oxenius, Oxenius A, Torti N, Brocker T, Rülicke T, Walton SM   +20 more
core   +2 more sources

Tissue-intrinsic γδ T cells critically regulate Tissue-Resident Memory CD8 T cells [PDF]

, 2022
Summary Because Tissue-Resident Memory T (T RM ) cells contribute critically to body-surface immunoprotection and/or immunopathology in multiple settings, their regulation is biologically and clinically important.
Llorian, Miriam, McKenzie, Duncan, García-Cassani, Bethania, Pavlova, Anna, Muñoz-Ruiz, Miguel, Jandke, Anett, Iannitto, Maria Luisa, Mavrigiannaki, Anna Maria, Hayday, Adrian, D’Antuono, Rocco, Ushakov, Dmitry   +10 more
core   +1 more source

Tissue-resident memory T cells in cytomegalovirus infection [PDF]

Current Opinion in Virology, 2016
Herpesviruses establish life-long infection in their hosts and maintain latent reservoirs for sporadic reactivation at peripheral sites, such as skin and mucosae. For herpes simplex virus infection, experimental studies in mice revealed that immediate protection against local reactivation or superinfection events in the skin relies on tissue resident ...
Thom Jenny Tosca, Oxenius Annette
openaire   +3 more sources

Rapid turnover of effector-memory CD4(+) T cells in healthy humans [PDF]

, 2004
Memory T cells can be divided into central-memory (T(CM)) and effector-memory (T(EM)) cells, which differ in their functional properties. Although both subpopulations can persist long term, it is not known whether they are maintained by similar ...
Peter C.L. Beverley, Macallan, DC, Griffin, GE, George E. Griffin, Andrew T. Worth, Derek C. Macallan, Wallace, Diana, Diana Wallace, Ghattas, Hala, Zhang, Yan, Griffin, George E, Macallan, Derek C, Zhang, Y, Ghattas, H, Beverley, Peter CL, Tough, David F, Hala Ghattas, Tough, DF, David F. Tough, De Lara, C, De Lara, Catherine, Beverley, PC, Yan Zhang, Catherine de Lara, Wallace, D, Worth, Andrew T, Worth, AT   +26 more
core   +1 more source

Supplementary Data from Dopamine Signaling Promotes Tissue-Resident Memory Differentiation of CD8⁺ T Cells and Antitumor Immunity

, 2022
Supplementary Data from Dopamine Signaling Promotes Tissue-Resident Memory Differentiation of CD8+ T Cells and Antitumor ...
Yingtong Lin (2814325), Jinzhu Feng (14957433), Yiwen Zhang (14957442), Yingshi Chen (11334825), Zhilin Peng (11334822), Likai Tan (14957436), Wenjing Huang (172392), Shu-Mei Yan (283134), Zeyu Pu (14957430), Feng Huang (62988), Xin He (14957439), Hongrong Hu (7487525), Yuzhuang Li (11334828), Hui Zhang (7197)   +13 more
core   +1 more source

FGL2-targeting T cells exhibit antitumor effects on glioblastoma and recruit tumor-specific brain-resident memory T cells [PDF]

, 2023
Although tissue-resident memory T (TRM) cells specific for previously encountered pathogens have been characterized, the induction and recruitment of brain TRM cells following immune therapy has not been observed in the context of glioblastoma.
Kong, Lingyuan, Yi, Sofia F, Masopust, David, Hashizume, Rintaro, Hu, Jiemiao, Heimberger, Amy B, Jia, Zhiliang, Wang, Jing, Li, Shulin, Tian, Xiangjun, Zhao, Qingnan, Dao, Long Hoang, Jiang, Shan, Fowlkes, Natalie Wall, Yan, Jun, Xia, Xueqing, David Masopust, Shulin Li, Heimberger, Amy B., Xiangjun Tian, Natalie Wall Fowlkes, Amy B. Heimberger, Jun Yan, Rintaro Hashizume, Long Hoang Dao, Shan Jiang, Zhiliang Jia, Qingnan Zhao, Jing Wang, Sofia F. Yi, Lingyuan Kong, Xueqing Xia, Jiemiao Hu, Yi, Sofia F.   +33 more
core   +1 more source

Tissue resident memory T cells and viral immunity [PDF]

Current Opinion in Virology, 2017
Tissue resident memory T cells (TRM) constitute a recently identified T cell lineage that is responsible for frontline defense against viral infections. In contrast to central and effector memory T cells, which constitutively recirculate between tissues and blood, TRM reside permanently within tissues. As the main surveyors of non-lymphoid tissues, TRM
Pamela C, Rosato, Lalit K, Beura, David, Masopust   +2 more
openaire   +2 more sources

CD301b+ dendritic cells stimulate tissue-resident memory CD8+ T cells to protect against genital HSV-2

Nature Communications, 2016
Tissue-resident memory T cells are needed for optimal antiviral immunity at mucosal surfaces. Here the authors provide a mechanism for this protection, showing that vaginal CD301b+ DC-dependent IFN-γ production by CD8+ tissue-resident memory T cells, not
Haina Shin, Yosuke Kumamoto, Smita Gopinath, Akiko Iwasaki   +3 more
doaj   +1 more source

Tissue resident memory T cells inhabit the deep human conjunctiva

Scientific Reports, 2022
Mucosal linings of the body, including the conjunctiva, are enriched in tissue-resident memory T cells (TRMs) whose defining feature is their continual tissue protection that does not rely on migration to lymphoid organs to elicit immune responses ...
Racha Arnous, Sana Arshad, Kerrie Sandgren, Anthony L. Cunningham, Nicole Carnt, Andrew White   +5 more
doaj   +1 more source

The Roles of Tissue-Resident Memory T Cells in Lung Diseases [PDF]

Frontiers in Immunology, 2021
The unique environment of the lungs is protected by complex immune interactions. Human lung tissue-resident memory T cells (TRM) have been shown to position at the pathogen entry points and play an essential role in fighting against viral and bacterial pathogens at the frontline through direct mechanisms and also by orchestrating the adaptive immune ...
Rui Yuan, Jiang Yu, Ziqiao Jiao, Jinfei Li, Fang Wu, Rongkai Yan, Xiaojie Huang, Chen Chen, Chen Chen   +8 more
openaire   +3 more sources