Results 91 to 100 of about 62,626 (262)
Giant FAZ10 is required for flagellum attachment zone stabilization and furrow positioning in Trypanosoma brucei [PDF]
The flagellum and flagellum attachment zone (FAZ) are important cytoskeletal structures in trypanosomatids, being required for motility, cell division and cell morphogenesis.
Baqui, Munira M.A. +3 more
core +1 more source
Mechanical regulation of Titin N2B-us conformation and its binding to FHL2 [PDF]
Yuze Sun +3 more
openalex +1 more source
Proteome‐Wide Analysis of Human Deletions
ABSTRACT Protein deletions are frequent among both natural and pathogenic variations. Many of them are misclassified in variation databases and the literature. Nonsense‐mediated decay prevents the expression of many nucleotide deletions. Many variants classified as protein deletions are not expressed at all.
Haoyang Zhang +2 more
wiley +1 more source
Titin is an extraordinary long multidomain protein spanning half of the sarcomeric unit. One end of the titin filament is known to emerge from the Z-line, but the precise localization of the other end is still a matter of debate.
Dan Eremia
doaj +1 more source
Titin Isoform Size is Not Correlated with Thin Filament Length in Rat Skeletal Muscle
The mechanisms controlling thin filament length in muscle remain controversial. It was recently reported that thin filament length was related to titin size, and that the latter might be involved in thin filament length determination.
Marion Lewis Greaser +1 more
doaj +1 more source
This study comprehended the allergen profiles of six edible crab species using proteomic and transcriptomic analyses and identified 11 putative allergens. King crab has a distinct protein and allergen profile, with the discovery of malate dehydrogenase as a novel king crab‐specific allergen registered as Para c 11.
Shanshan Li +11 more
wiley +1 more source
Heterogeneous and rate-dependent streptavidin-biotin unbinding revealed by high-speed force spectroscopy and atomistic simulations [PDF]
Receptor-ligand interactions are essential for biological function and their binding strength is commonly explained in terms of static lock-and-key models based on molecular complementarity.
Gonzalez, Laura +4 more
core +4 more sources
Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy
Cerebral palsy, caused by non‐progressive brain injury, is frequently accompanied by skeletal muscle alterations. This review synthesizes current evidence from muscle biopsy studies, revealing cellular and molecular adaptations in muscle tissue. Abstract Cerebral palsy (CP), the most prevalent childhood‐onset motor disability, frequently entails ...
Sebastian Edman +4 more
wiley +1 more source
Summary Myopathies encompass a wide variety of acquired and hereditary disorders. The pathomechanisms include structural and functional changes affecting, e.g., myofiber metabolism and contractile properties.
Andreas Unger +9 more
doaj +1 more source
Compliant Titin Isoform Content Is Reduced in Left Ventricles of Sedentary Versus Active Rats
A sedentary lifestyle is associated with increased cardiovascular risk factors and reduced cardiac compliance when compared to a lifestyle that includes exercise training.
Charles S. Chung +3 more
doaj +1 more source

