Results 81 to 90 of about 62,626 (262)

Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism. [PDF]

open access: yes, 2019
Biological roles of obscurin and its close homolog Obsl1 (obscurin-like 1) have been enigmatic. While obscurin is highly expressed in striated muscles, Obsl1 is found ubiquitously.
Blondelle, Jordan   +13 more
core   +1 more source

New Religious Authority of Islamic Millennial: A Study of Rohis Community in Medan City [PDF]

open access: yes, 2019
Teenagers, or today mostly known as millennial generation, is transition phase from the child to the adult category. They look for identity through various activities such as Rohis community.
Sumanti, Solihah Titin
core   +1 more source

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad   +9 more
wiley   +1 more source

Unexpected Low Mechanical Stability of Titin I27 Domain at Physiologically Relevant Temperature.

open access: yesJournal of Physical Chemistry Letters, 2021
The extensively studied immunoglobulin (Ig) domain I27 of the giant force-bearing protein titin has provided a basis for our current understanding of the structural stability, dynamics, and function of the numerous mechanically stretched Ig domains in ...
Miao Yu, Juanjuan Lu, Shimin Le, Jie Yan
semanticscholar   +1 more source

Prevalence and Mechanisms of Sustained Force Production in the Musculature of the Southern Alligator Lizard (Elgaria multicarinata)

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The southern alligator lizard (Elgaria multicarinata) exhibits prolonged mate‐holding behavior. This behavior maybe be underpinned by a phenomenon known as sustained force, observed in the jaw muscles of this species, in which the muscle fails to relax between subsequent contractions.
Allyn Nguyen   +3 more
wiley   +1 more source

A New Paradigm for Muscle Contraction

open access: yesFrontiers in Physiology, 2015
For the past 60 years, muscle contraction had been thought to be governed exclusively by the contractile filaments, actin and myosin. This thinking explained most observations for concentric and isometric, but not for eccentric muscle contractions.
Walter eHerzog   +3 more
doaj   +1 more source

Unusual Mobility of the Elastic Protein Titin in Thirteen-Lined Ground Squirrel Hearts [PDF]

open access: bronze, 2021
Jonathan R. Groening   +6 more
openalex   +1 more source

Reduced Dietary Protein Induces Changes in the Dental Proteome

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs   +2 more
wiley   +1 more source

Detection of titin fragments in urine in response to exercise-induced muscle damage. [PDF]

open access: yesPLoS ONE, 2017
Many studies have attempted to determine the associations between blood biomarkers and exercise-induced muscle damage. However, poor correlations between the changes in biomarker levels and the magnitude of muscle symptoms have been reported.
Kazue Kanda   +4 more
doaj   +1 more source

Equations for Stochastic Macromolecular Mechanics of Single Proteins: Equilibrium Fluctuations, Transient Kinetics and Nonequilibrium Steady-State

open access: yes, 2001
A modeling framework for the internal conformational dynamics and external mechanical movement of single biological macromolecules in aqueous solution at constant temperature is developed.
Qian, Hong
core   +1 more source

Home - About - Disclaimer - Privacy