Results 131 to 140 of about 1,869 (165)

Behavioural and electroencephalographic effects of Tityus serrulatus scorpion venom in rats

Toxicon, 1993
This study was designed to investigate the convulsant effects of T. serrulatus scorpion venom in rats. Pretreatment of rats with venom increased the minimum convulsant dose of picrotoxin, impaired convulsion generalization and displaced to the left the dose-response curve for picrotoxin.
V.A.C. Dorce, M.R.L. Sandoval
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Tityus serrulatus venom peptidomics: Assessing venom peptide diversity

Toxicon, 2008
MALDI-TOF-TOF and de novo sequencing were employed to assess the Tityus serrulatus venom peptide diversity. Previous works has shown the cornucopia of molecular masses, ranging from 800 to 3000Da, present in the venom from this and other scorpions species. This work reports the identification/sequencing of several of these peptides. The majority of the
Breno Rates, Márcia Helena Borges, Michael K. Richardson, Adriano Monteiro de Castro Pimenta, Karla K.F. Ferraz, Maria Elena de Lima   +5 more
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Immune cells recruitment and activation by Tityus serrulatus scorpion venom

Toxicon, 2011
Despite several studies showed that the Tityus serrulatus scorpion venom (Tsv) induces an inflammatory response, just a few have investigated the effect of the venom on the immune response. Therefore, the aim of this study was to evaluate alterations of venom application on lymphoid organs and on the recruitment and activation of cells and also on the ...
Anne Karine Martins Assunção, Márcia C.G. Maciel, Lucilene A. Silva, Flávia R.F. Nascimento, Eder Magalhães Silva Fialho, Rosane N. M. Guerra, Aramys Silva Reis, Thiare S. Fortes, Fábio H. Kwasniewski, Arlley C.B. Silva   +9 more
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Effect of the venom of the scorpion Tityus serrulatus on adrenal gland catecholamines

Toxicon, 1968
Abstract A sublethal dose of the venom of the scorpion Tityus serrulatus produced a depletion of adrenal gland catecholamines. This effect was blocked on denervation of the adrenals. The action of the venom on the chromaffin granules in vitro was not observed. Certain fractions of the venom elicited the same effects as the whole venom.
G. Gazzinelli, Marcus Vinicius Gomez, M. Celeste Henriques, Carlos R. Diniz   +3 more
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Renal effects and vascular reactivity induced by Tityus serrulatus venom

Toxicon, 2005
Tityus serrulatus, popularly known as yellow scorpion, is one of the most studied scorpion species in South America and its venom has supplied some highly active molecules. The effects of T. serrulatus venom upon the renal physiology in human showed increased renal parameters, urea and creatinine.
Alves, R. D., do Nascimento, NRF, Barbosa, PSF, Kerntopf, M. R., Lessa, LMA, de Sousa, C. M., Martins, R. D., Sousa, D. F., de Queiroz, MGR, Toyama, M. H., Fonteles, M. C., Martins, AMC, Monteiro, HSA   +12 more
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Ipomoea asarifolia neutralizes inflammation induced by Tityus serrulatus scorpion venom

Journal of Ethnopharmacology, 2014
Envenoming caused by scorpion sting is a serious public health problem. In Brazil, 13,038 accidents caused by venomous animals have been reported. Of this total, 53% of the cases and 14 deaths were caused by scorpions. Furthermore, Tityus serrulatus (Buthidae) is the most dangerous scorpion due to the high toxicity of its venom.
Arnóbio Antônio da Silva-Júnior, Allanny Alves Furtado, Ruth Medeiros Oliveira, Mariana Angélica Oliveira Bitencourt, Silvana Maria Zucolotto, Denise V. Tambourgi, Matheus F. Fernandes-Pedrosa, Maira Conceição Jerônimo de Souza Lima, Hugo Alexandre Oliveira Rocha, Eryvaldo Sócrates Tabosa do Egito   +9 more
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Serum levels of cytokines in patients envenomed by Tityus serrulatus scorpion sting

Toxicon, 1999
Seventeen patients stung by Tityus serrulatus scorpion were classified as mild (pain at the site of the sting, n = 6), moderate (local pain and one of the following manifestations: vomiting, psychomotor agitation, prostration, sweating, tachypnea, tachycardia and mild arterial hypertension, n = 10) and severe cases (equal moderate cases plus cardiac ...
Mônica de Mônico Magalhães, Carlos Faria Santos Amaral, Nilton Alves de Rezende, Ricardo T. Gazzinelli, Ricardo T. Gazzinelli, Maria Elizabeth S Pereira, Fábio Bucaretchi, José Renan Cunha-Melo, Delio Campolina   +8 more
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Purification and partial characterization of a second toxin from the scorpion Tityus serrulatus

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1976
1. 1. A purification procedure is described for a second toxin of T. serrulatus, which also can be used with advantage for toxin I. 2. 2. Aminoacid compositions of toxins I and II were determined. 3. 3. Molecular weight of the toxins, were 6400 and 7700, respectively for toxins I and II. 4. 4.
David Toledo, Armando G.A. Neves
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Tityus serrulatus Hypotensins: A new family of peptides from scorpion venom

Biochemical and Biophysical Research Communications, 2008
Using a proteomic approach, a new structural family of peptides was put in evidence in the venom of the yellow scorpion Tityus serrulatus. Tityus serrulatus Hypotensins (TsHpt) are random-coiled linear peptides and have a similar bradykinin-potentiating peptide (BPP) amino acid signature.
Verano-Braga, T., Rocha-Resende, C., Silva, D. M., Ianzer, D., Martin-Eauclaire, M. F., Bougis, P. E., de Lima, M. E., Santos, R. A. S., Pimenta, A. M. C.   +8 more
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Potassium channel blockers from the venom of the Brazilian scorpion Tityus serrulatus ( )

Toxicon, 2016
Potassium (K(+)) channels are trans-membrane proteins, which play a key role in cellular excitability and signal transduction pathways. Scorpion toxins blocking the ion-conducting pore from the external side have been invaluable probes to elucidate the structural, functional, and physio-pathological characteristics of these ion channels.
Adriano Marçal Pimenta, Marie-France Martin-Eauclaire, Maria-Elena De Lima, Pierre E. Bougis   +3 more
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