Results 1 to 10 of about 11,832,408 (324)
Association of TLR-4 896A/G, TLR-4 1196C/T, and TLR-9 C/T polymorphism with schizophrenia in Indian Bengalee patient [PDF]
Indian Journal of Psychiatry, 2022 Background: Chronic low-grade inflammation triggered by viral agents is a suggested etiological factor for schizophrenia. However, the underlying mechanism of inflammation and genetic predisposition to schizophrenia is poorly understood.
Jiwan Gurung +3 more
doaj +4 more sources
Effects of Separate and Concomitant TLR-2 and TLR-4 Activation in Peripheral Blood Mononuclear Cells of Newborn and Adult Horses. [PDF]
PLoS ONE, 2013 Deficient innate and adaptive immune responses cause newborn mammals to be more susceptible to bacterial infections than adult individuals. Toll-like receptors (TLRs) are known to play a pivotal role in bacterial recognition and subsequent immune ...
Johannes Cornelis Vendrig +2 more
doaj +23 more sources
TLR-4 Inhibition Attenuates Inflammation, Thrombosis, and Stenosis in Arteriovenous Fistula in Yucatan Miniswine. [PDF]
Cardiol Cardiovasc Med, 2022 Arteriovenous fistula (AVF) is the preferred vascular access in hemodialysis patients; however, it is afflicted with a high failure rate. Chronic inflammation, excessive neointimal hyperplasia (NIH), vessel stenosis, early thrombosis, and failure of ...
Rai V +5 more
europepmc +2 more sources
Randomized controlled trial of vitamin d supplementation on toll-like receptor-2 (tlr-2) and toll-like receptor-4 (tlr-4) in tuberculosis spondylitis patients [PDF]
Journal of Orthopaedic Surgery and Research, 2023 Background Tuberculosis spondylitis accounts for approximately 50% of all cases of skeletal tuberculosis. Vitamin D plays a role in the immune system. Vitamin D helps in the activation of TLR-2 and TLR-4, which play a role in the process of tuberculosis ...
Jainal Arifin +5 more
doaj +2 more sources
Frontiers in Immunology, 2020 Chromoblastomycosis is a chronic and progressive subcutaneous mycosis caused mainly by the fungus Fonsecaea pedrosoi. The infection is characterized by erythematous papules and histological sections demonstrating an external layer of fibrous tissue and ...
Leandro Carvalho Dantas Breda +11 more
doaj +2 more sources
Molecules, 2022 Plants are an important source of drug development and numerous plant derived molecules have been used in clinical practice for the ailment of various diseases.
A. Khan +10 more
semanticscholar +1 more source
Oxidative Medicine and Cellular Longevity, 2021 Silicosis remains one of the most serious diseases worldwide, with no effective drug for its treatment. Our research results have indicated that arctiin and arctigenin could increase the mitochondrial membrane potential, which in turn reduces the ...
Xueying Liu +6 more
semanticscholar +1 more source
Frontiers in Genetics, 2023 Background: An increasing number of studies have suggested the relationship between single-nucleotide polymorphisms (SNPs) in toll-like receptor (TLR) genes and gastric cancer (GC) susceptibility; however, the available evidence is contradictory.
Ayoub Al Othaim +8 more
doaj +1 more source
Mediators of Inflammation, 2022 Alzheimer's disease (AD) is characterized by chronic neuroinflammation, which is partially mediated by dysregulated functions of glial cells. Cardiolipin (CL) is a phospholipid normally confined to the inner mitochondrial membrane; however, it has been ...
T. Murray +5 more
semanticscholar +1 more source
Journal of Immunology, 2021 IFN-γ, a proinflammatory cytokine produced primarily by T cells and NK cells, activates macrophages and engages mechanisms to control pathogens. Although there is evidence of IFN-γ production by murine macrophages, IFN-γ production by normal human ...
Niranjala Gajanayaka +11 more
semanticscholar +1 more source