Results 121 to 130 of about 262,724 (386)
Veterinární Medicína, 2014 To date, only limited information about the influence of ovarian hormones on canine immune system cells has been available. The study investigated the in vitro influence of progesterone and estradiol-17β on the activity of canine neutrophils.
A. Bartoskova +6 more
doaj +1 more source
Caspase-8 controls the gut response to microbial challenges by Tnf-alpha-dependent and independent pathways [PDF]
, 2014 Objectives: Intestinal epithelial cells (IEC) express toll-like receptors (TLR) that facilitate microbial recognition. Stimulation of TLR ligands induces a transient increase in epithelial cell shedding, a mechanism that serves the antibacterial and ...
Basic, Marijana +12 more
core +3 more sources
TLR4 as a negative regulator of keratinocyte proliferation
PLOS ONE, 2017 TLR4 is an innate immune receptor with expression in human skin, keratinocytes as well as squamous cell carcinoma (SCC) of the skin. In the present study we investigate the role of TLR4 as a negative regulator of keratinocyte proliferation. We present here that the expression of TLR4 increased with the differentiation of cultured keratinocytes in a ...
Iotzova-Weiss, Guergana +8 more
openaire +6 more sources
A Peptide Antagonist of the TLR4–MD2 Interaction [PDF]
ChemBioChem, 2009 AbstractToll‐like receptors are an integral part of innate immunity in the central nervous system (CNS); they orchestrate a robust defense in response to both exogenous and endogenous danger signals. Recently, toll‐like receptor 4 (TLR4) has emerged as a therapeutic target for the treatment of CNS‐related diseases such as sepsis and chronic pain.
Slivka, P. +11 more
openaire +3 more sources
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Asian Pacific Journal of Tropical BiomedicineObjective: To evaluate the anti-inflammatory effect of black cumin seed oil (BCSO) and its nanoemulsion on lipopolysaccharide (LPS)-induced liver injury in mice. Methods: LPS-induced acute liver injury mouse model was used to evaluate the effects of BCSO
Hesham Haffez +3 more
doaj +1 more source
International Journal of COPD, 2021 Fujun Zhou,1,* Cheng Cao,2,* Huiping Chai,2 Jingfang Hong,3 Min Zhu1 1Department of Health and Nursing, Anhui Vocational College of City Management, Hefei City, Anhui Province, People’s Republic of China; 2Department of Thoracic Surgery, 4th ...
Zhou F, Cao C, Chai H, Hong J, Zhu M
doaj
Marine Drugs, 2019 Fucoxanthin (Fx) is a natural extract from marine seaweed that has strong antioxidant activity and a variety of other bioactive effects. This study elucidated the protective mechanism of Fx on alcoholic liver injury.
Jiawen Zheng +6 more
doaj +1 more source
Molecular Study of Colibacillosis Susceptibility in Calves and Lambs
Nano Biomedicine and Engineering, 2020 Single nucleotide polymorphism (SNP) is hereditary change in a DNA sequence that occurs when a single nucleotide in a genome is modified; SNPs are usually considered to be point mutations that have been evolutionarily successful enough to recur in a ...
Hawraa Judi +2 more
doaj +1 more source
Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing [PDF]
, 2007 Airway infection by the Gram-positive pathogen Streptococcus pneumoniae (Sp) leads to recruitment of neutrophils but limited bacterial killing by these cells.
Clarke, Thomas B. +6 more
core +3 more sources