Results 221 to 230 of about 262,724 (386)

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang   +7 more
wiley   +1 more source

Therapeutic targeting of myeloid cells in liver fibrosis: Mechanisms and clinical prospects

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review systematically summarizes the origin, recruitment, and differentiation regulation mechanisms of myeloid cells in driving hepatic fibrosis progression. By targeting these three critical phases, potential therapeutic strategies for liver fibrosis can be explored.
Yue Wang   +5 more
wiley   +1 more source

Asthma and coagulation [PDF]

open access: yes, 2013
Hammad, Hamida, Lambrecht, Bart
core   +1 more source

Involvement of Toll-like Receptor (TLR) 2 and TLR4 in Cell Activation by Mannuronic Acid Polymers [PDF]

open access: hybrid, 2002
Trude H. Flo   +10 more
openalex   +1 more source

The Importance of LPCAT2 in TLR4 Signalling

open access: yes, 2019
Real Time quantitative PCR and ELISA analysis showed that the knockdown of LPCAT2 gene reduces the gene and protein expression of pro-inflammatory cytokines, thereby suppressing LPS-induced macrophage inflammatory responses. However, the mechanism of action of LPCAT2 is not yet uncovered.
openaire   +1 more source

A potential strategy for improving offspring behavior in maternal immune activation: Amantadine‐mediated suppression of neuroinflammation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Amantadine (AMA) regulates neurocyte apoptosis and inhibits neurocyte inflammation to prevent maternal immune activation (MIA) from affecting offspring behavior. Abstract Background Maternal viral infection during pregnancy can lead to maternal immune activation (MIA), increasing the risk of neurodevelopmental disorders in offspring.
Jianfei Wu   +8 more
wiley   +1 more source

Palmitic acid enhances TLR4 expression and promotes resistin/TLR4 signalling [PDF]

open access: yesEndocrine Abstracts, 2015
Mohammed Taouis   +3 more
openaire   +2 more sources

Research progress on traditional Chinese medicine animal models of post‐stroke depression and pathological insights

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Post‐stroke depression (PSD) animal model of traditional Chinese medicine (TCM) combined with disease and syndrome often uses western medicine surgery (including: middle cerebral artery embolization to construct cerebral ischemia, or brain injection of collagenase to construct cerebral hemorrhage) combined with other methods (including: isolation ...
Jielin Wang   +4 more
wiley   +1 more source

Potential Application of a Water‐Soluble Fullerene C60 Decorated with Diethylene Glycol in Treatment of Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
A new ethoxyethanol derivative of iminofullerene, F2, is synthesized and labeled with 99mTc to produce 99mTc‐F2. In vitro, compound F2 inhibits the activation of primary mouse bone marrow‐derived macrophages stimulated with lipopolysaccharide. Moreover, 99mTc‐F2 is selectively enriched in the injured joints of mice. Inflammatory macrophages play a role
Rui He   +6 more
wiley   +1 more source

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