Results 241 to 250 of about 237,895 (332)

Macrophage migration inhibitory factor of zoonotic <i>Giardia duodenalis</i> triggers TLR4-MAPK/AKT/NLRP3 pathways to regulate inflammatory response. [PDF]

iScience
Chen M, Zhang X, Liu Z, Wang X, Zhang X, Yang H, Lv B, Yu Y, Sun Z, Gong P, Zhang N, Li X, Li J.   +12 more
europepmc   +1 more source

Down-regulation of CXCL12/CXCDown-regulation of CXCL12/CXCR4 expression alleviates ischemia- reperfusion- induced inflammatory pain via inhibiting glial TLR4 activation in the spinal cord

, 2016
Xiaoqian Li
openalex   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

Journal of Intelligent Medicine, EarlyView.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran, Tarique Mahmood, Farogh Ahsan, Shahzadi Bano, Vaseem Ahamad Ansari, Mohd Adnan   +5 more
wiley   +1 more source

Effects of Defined Pig Microbiota on Acute Salmonellosis in Gnotobiotic Piglets. [PDF]

FASEB J
Splichal I, Polakova K, Sinkora M, Neuzil Bunesova V, Modrackova N, Vlkova E, Kindlova Z, Horvathova K, Splichalova A.   +8 more
europepmc   +1 more source

Peri‐implant disease pathogenesis animal models: Consensus report of Workgroup 1 of the IADR Implantology Research Group Best Evidence Consensus Symposium on Peri‐Implant Disease and Its Treatment

Journal of Periodontology, EarlyView.
Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis, Leonardo Mancini, Panos Afouxenides, Andrea Roccuzzo, IADR IRG Peri‐implantitis Best Evidence Consensus Working Group 1, Sukirth Ganesan   +5 more
wiley   +1 more source

TLR4 Induces PANoptosis in Annulus Fibrosus Cells by Activating NLRP12 in Intervertebral Disc Degeneration. [PDF]

J Inflamm Res
Zheng F, Cao L, Fu J, Luo M, Yue W, Ma Y, Chen B, Zhai Y, Liu C.   +8 more
europepmc   +1 more source

04132 Heme-driven pathologies in the context of infections: from TLR4 signaling to COVID-19

Diana Imhof
openalex   +1 more source

Phosphatidylinositol-4-kinase IIα licenses phagosomes for TLR4 signaling and MHC-II presentation in dendritic cells

, 2020
Cynthia López‐Haber, Roni Levin‐Konigsberg, Yueyao Zhu, Jing Bi‐Karchin, Tamás Balla, Sergio Grinstein, Michael S. Marks, Adriana R. Mantegazza   +7 more
openalex   +2 more sources

HOXA5 Suppresses NEK7‐Mediated Alveolar Epithelial Pyroptosis in Acute Lung Injury by Transcriptionally Inhibiting KAT2A

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Alveolar epithelial cell pyroptosis exacerbates inflammation and tissue damage by releasing inflammatory mediators, thereby promoting the development of acute lung injury (ALI). However, the fundamental mechanism underlying alveolar epithelial cell pyroptosis in ALI has not yet been elucidated. Lipopolysaccharide (LPS) was used to simulate ALI
Lei Wang, Heng Fan, Qi Wang, Cheng‐Jie Jiang, Dan‐Hui Li, Ji‐Hui Ye   +5 more
wiley   +1 more source

TLR agonists as adjuvants for viral vaccines: mechanisms, applications, and future directions. [PDF]

Front Microbiol
Shao F, Zhu X, Yi M, Gao H, Wu J, Fang R, Xie Y, Han J, Lu H.   +8 more
europepmc   +1 more source