IL-10 Released by Concomitant TLR2 Stimulation Blocks the Induction of a Subset of Th1 Cytokines That Are Specifically Induced by TLR4 or TLR3 in Human Dendritic Cells [PDF]
Fabio Re, Jack L. Strominger
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Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
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Upadacitinib Attenuates Lipopolysaccharide- and Cecal Ligation and Puncture-Induced Inflammatory Responses by Inhibiting NF-κB and Its Downstream Cytokines. [PDF]
Yao Q +5 more
europepmc +1 more source
Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao +6 more
wiley +1 more source
Novel bioinformatics approaches to design epitope-based vaccine against HIV latency by inquiring CTL epitopes and built-in adjuvants. [PDF]
Mashhadi Abolghasem Shirazi M +3 more
europepmc +1 more source
TLR4/Asp299Gly, CD14/C-260T, plasma levels of the soluble receptor CD14 and the risk of coronary heart disease: The PRIME Study [PDF]
Pierre‐Emmanuel Morange +10 more
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The role of cytokines in ovarian cancer drug resistance
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang +7 more
wiley +1 more source
Development and validation of a leukemia prognostic model through single-cell RNA sequencing and machine learning approaches. [PDF]
Chen D, Yang J, Wang M, Jian T.
europepmc +1 more source
RIP Links TLR4 to Akt and Is Essential for Cell Survival in Response to LPS Stimulation [PDF]
Marina Vivarelli +5 more
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