Results 61 to 70 of about 16,392 (208)
Cellular and Molecular Gastroenterology and Hepatology, 2016 Background & Aims: Innate immune dysfunction can promote chronic inflammatory diseases of the liver. For example, mice lacking the flagellin receptor Toll-like receptor 5 (TLR5) show microbial dysbiosis and predisposition to high-fat diet (HFD)-induced ...
Lucie Etienne-Mesmin +3 more
doaj +1 more source
eLife, 2020 Lung disease causes significant morbidity and mortality, and is exacerbated by environmental injury, for example through lipopolysaccharide (LPS) or ozone (O3). Toll-like receptors (TLRs) orchestrate immune responses to injury by recognizing pathogen- or
Salik Hussain +19 more
doaj +1 more source
iMetaMed, EarlyView.Clinical phases and classification of breast tumor dormancy. Tumor dormancy is described as the period after treatment until residual tumor cells become detectable as relapsing disease in clinic. During the period of clinical tumor dormancy, tumor mass dormancy and cellular dormancy may coexist.
Shu Chen +4 more
wiley +1 more source
Complete Aligned multi-FASTA of Toll-like Receptor 5 (TLR5) CDS
, 2022 Complete aligned multi-FASTA of Toll-like receptor 5 (TLR5) CDS for the following species: Salmo salar, Salmo trutta, Oncorhynchus tshawytscha, Oncorhynchus kisutch, Hucho hucho, Homo sapiens , Esox lucius, Oncorhynchus mykiss, Delphinapterus leucas ...
Elizabeth Ramirez (12218378) +3 more
core +1 more source
Contribution of TLR5 signaling.
, 2013 Tlr5−/− (gray bars) and C57BL/6N (black bars) mice were immunized with β-Gal alone or with indicated adjuvant. 0.2 µg of soluble flagellin and 106 IU of VREP constructs were used. Control mice were given VREP-OVA.
Maria L. Knudsen (421511) +9 more
core +1 more source
Rheumatology &Autoimmunity, EarlyView.Sera from patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease (ILD) exhibit significantly higher type I interferon (IFN‐I) bioactivity and interferon‐stimulated gene‐inducing activity compared to anti‐ARS‐positive ILD and healthy controls.
Shohei Nakamura +3 more
wiley +1 more source
The role of TRIF protein in regulating the proliferation and antigen presentation ability of myeloid dendritic cells through the ERK1/2 signaling pathway in chronic low-grade inflammation of intestinal mucosa mediated by flagellin-TLR5 complex signal [PDF]
PeerJObjective The objective is to explore whether the flagellin-TLR5 complex signal can enhance the antigen presentation ability of myeloid DCs through the TRIF-ERK1/2 pathway, and the correlation between this pathway and intestinal mucosal inflammation ...
Zhaomeng Zhuang +3 more
doaj +2 more sources
Polymorphisms in the TLR4 and TLR5 gene are significantly associated with inflammatory bowel disease in German shepherd dogs. [PDF]
PLoS ONE, 2010 Inflammatory bowel disease (IBD) is considered to be the most common cause of vomiting and diarrhoea in dogs, and the German shepherd dog (GSD) is particularly susceptible.
Aarti Kathrani +6 more
doaj +1 more source
Monocytes Derived From Human Pluripotent Stem Cells Engineered for Detection of Pyrogens
Cell Proliferation, EarlyView.In summary, we have developed a monocyte‐based reporter system using hESC‐Mono for interrogating the NF‐κB signalling axis, a central pathway governing pyrogenic responses. Our platform enables rapid and dose‐dependent detection of both endotoxins (LPS) and non‐endotoxins (LTA and Zymosan).
Jingjing Liu +8 more
wiley +1 more source
Generation of TLR5 knockout mice.
, 2016 A: genotyping results (WT-wild type, HT-heterozygous, KO-knockout); B: Real-time PCR quantified mRNA levels of TLR5 in wild-type (WT) and knockout mice (TLR5KO), adipose tissue and colon tissue were shown. C: Real-time PCR products were run on 1% agarose
W. Timothy Garvey (113627) +5 more
core +1 more source