Results 101 to 110 of about 74,934 (299)
The Role of Dysregulated Neuroinflammatory Molecular Pathways in Parkinson Disease: A Systematic Review [PDF]
Caspian Journal of Neurological SciencesBackground: Parkinson disease (PD) is a prevalent neurodegenerative disorder affecting dopaminergic neurons in the substantia nigra (SN). Neuroinflammation has a vital role in PD pathophysiology.
Mohammadreza Kosari +12 more
doaj
T granules in human platelets function in TLR9 organization and signaling [PDF]
, 2012 Human and murine platelets (PLTs) variably express toll-like receptors (TLRs), which link the innate and adaptive immune responses during infectious inflammation and atherosclerotic vascular disease.
Aslam, Rukhsana +11 more
core +2 more sources
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2019 Receptorii Toll-like recunosc structurile moleculare legate de agentul patogen a micobacterii și, astfel, joacă un rol important în protecţia organismului faţă de infecţia tuberculoasă.
Alexandru Varzari +5 more
doaj
Toll‐Like Receptor 9 Plays a Pivotal Role in Angiotensin II–Induced Atherosclerosis
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Toll‐like receptor (TLR) 9 recognizes bacterial DNA, activating innate immunity, whereas it also provokes inflammation in response to fragmented DNA released from mammalian cells.
Daiju Fukuda +19 more
doaj +1 more source
Critical role of toll-like receptor 9 in morphine and Mycobacterium tuberculosis-Induced apoptosis in mice. [PDF]
PLoS ONE, 2010 Although it is established that opioid and Mycobacterium tuberculosis are both public health problems, the mechanisms by which they affect lung functions remain elusive.We report here that mice subjected to chronic morphine administration and M ...
Lin Chen +11 more
doaj +1 more source
Journal of Cellular and Molecular Medicine, 2019 Excessive neutrophil extracellular trap (NET) formation may contribute to polymyositis (PM)‐associated interstitial lung diseases (ILD), but the underlying mechanism is not fully revealed.
Sigong Zhang +9 more
semanticscholar +1 more source
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
Journal of Mazandaran University of Medical Sciences, 2019 Background and purpose: Hepatocellular carcinoma (HCC) is a most common liver malignancy and TLR9 (Toll-like receptor) is essential for CpG DNA-induced immune responses.
Arezou Rezaei +4 more
doaj
Frontiers in Immunology, 2018 Toll-like receptor 9 (TLR9) belongs to the group of endosomal receptors of the innate immune system with the ability to recognize hypomethylated CpG sequences from DNA.
Erika Aurora Martínez-García +14 more
doaj +1 more source