Results 141 to 150 of about 25,778 (287)

TMAO Is Both a Biomarker and a Renal Toxin [PDF]

Circulation Research, 2015
In 2011, Hazen and colleagues1 made the seminal discovery that 3 metabolites of dietary phosphatidylcholine (choline, trimethylamine N-oxide [TMAO] and betaine) predicted risk for cardiovascular disease in an independent large clinical cohort. They also demonstrated that supplementing the diet with choline or TMAO promoted atherosclerosis in a mouse ...
openaire   +2 more sources

Mechanism of TMAO-mediated NLRP3 inflammasome in the pathogenesis of large artery atherosclerosis in the head and neck

徐州医科大学学报
Objective To screen for specific metabolites in patients with large artery atherosclerosis (LAA) in the head and neck and to verify whether these metabolic markers can upregulate the NLR family pyrin domain containing protein 3 (NLRP3) inflammasome to ...
CHEN Zhiren, HUANG Zehua, YANG Meifang, ZHOU Zixuan, CHEN Weiwei, WANG Peian   +5 more
doaj   +1 more source

Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia

Alzheimer's Research & Therapy
AbstractBackgroundThe gut-derived metabolite Trimethylamine N-oxide (TMAO) and its precursors - betaine, carnitine, choline, and deoxycarnitine – have been associated with an increased risk of cardiovascular disease, but their relation to cognition, neuroimaging markers, and dementia remains uncertain.MethodsIn the population-based Rotterdam Study, we ...
Yaqub, A, Vojinovic, D, Vernooij, MW, Slagboom, PE, Ghanbari, M, Beekman, M, van der Grond, J, Hankemeier, T, van Duijn, CM, Ikram, MA, Ahmad, S   +10 more
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Role of Trimethylamine N‐Oxide in Assessing Plaque Instability of the Culprit Lesion in Chinese Patients With ST‐Elevation Myocardial Infarction: Insights From a 7‐Year Long‐Term Follow‐Up Study

Clinical and Translational Science
This study investigated the relationship between trimethylamine N‐oxide (TMAO) levels and plaque instability in Chinese patients with ST‐elevation myocardial infarction (STEMI) using optical coherence tomography (OCT), with a 7 ‐year follow‐up.
Lili Xiu, Peng Zhao, Xia Gu, Bo Yu
doaj   +1 more source

Organic Arsenic in the Soil Environment: Speciation, Occurrence, Transformation, and Adsorption Behavior [PDF]

, 2018
An attempt is made to describe the fate and behavior of organic arsenic (As) compounds in the soil environment, based on an extensive literature researches.
Decker, Berryinne, Hu, Kan-Nian, Huang, Jen-How   +2 more
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When does TMAO fold a polymer chain and urea unfold it? [PDF]

, 2013
Jagannath Mondal, Guillaume Stirnemann, B. J. Berne   +2 more
openalex   +1 more source

Trimethylamine-N-Oxide (TMAO) and Predicted Risk of Cardiovascular Events After Partial Nephrectomy

, 2022
Ning Kang, Longbin Xiong, Zhixing Guo, Yuchen Li, Xiaohua Liu, Yulu Peng, Yuanzhong Yang, Huiming Liu, Xiangpeng Zou, Jun Wang, Boxin Zhao, Pei Dong, Fangjian Zhou, Chunping Yu, Xia Zheng, Steven C. Campbell, Zhiling Zhang   +16 more
openalex   +1 more source

TMAO metaorganismal pathway and chronic inflammatory diseases

Exploration of Medicine
Nutrients containing a trimethylamine (TMA) moiety in their structure can be metabolized by the gut microbiota through enzymatic cleavage of the C-N bond, producing TMA. In the liver, TMA is subsequently oxidized to trimethylamine N-oxide (TMAO) by flavin monooxygenases (FMOs).
Zeneng Wang, Shumei Man, Robert Koeth
openaire   +2 more sources

The Gut-Arterial Stiffness Axis: Is TMAO a Novel Target to Prevent Age-Related Aortic Stiffening? [PDF]

, 2021
Gary L. Pierce, Stephen J. Roy, Colin J. Gimblet   +2 more
openalex   +1 more source

Evaluation of Quality Deterioration of Marine Shellfish During Storage at Different Temperatures [PDF]

, 2004
Study on evaluation of fish freshness has been carried out using several parameters such as chemical, sensory, and physical parameter in which each has its own merits and demerits.
Agustini, T. W. (Tri)
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