Results 11 to 20 of about 16,874 (230)
Background Diet Influences TMAO Concentrations Associated with Red Meat Intake without Influencing Apparent Hepatic TMAO-Related Activity in a Porcine Model [PDF]
Metabolites, 2020 Red meat has been associated with an increased cardiovascular disease (CVD) risk, possibly through gut microbial-derived trimethylamine-N-oxide (TMAO).
Rebekka Thøgersen +7 more
doaj +5 more sources
TMAO: How gut microbiota contributes to heart failure. [PDF]
Translational Research, 2020 An increasing amount of evidence reveals that the gut microbiota is involved in the pathogenesis and progression of various cardiovascular diseases.
Yixin Zhang +3 more
semanticscholar +3 more sources
TMAO: a potential mediator of clopidogrel resistance [PDF]
Scientific Reports, 2021 Trimethylamine-N-oxide (TMAO) can activate platelets and increase thrombosis risk in clinical and experimental models. Meanwhile, the patients with coronary artery disease have higher serum TMAO level.
Ruisong Ma +5 more
doaj +3 more sources
Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk
Cell, 2016 Weifei Zhu, Elin Org, Nilaksh Gupta
exaly +2 more sources
Hydrophobic association and solvation of neopentane in urea, TMAO and urea–TMAO solutions [PDF]
Physical Chemistry Chemical Physics, 2021 Hydrophobic associations in pure water, urea solution, TMAO solution and urea-TMAO solution were studied using molecular dynamics simulations.
Timir Hajari +2 more
openaire +2 more sources
Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Atherosclerosis is the thickening or hardening of the arteries which is caused by a buildup of atheromatous plaque in the inner lining of an artery. Hypercholesterolemia, inflammation, oxidative stress, and trimethylamine N-oxide (TMAO) are important ...
Milad Abdi +2 more
doaj +1 more source
Blood, 2020 In this issue of Blood, Wu and colleagues report that trimethylamine N-oxide (TMAO), an intestinal microbiome-dependent metabolite, worsens graft-versus-host disease (GVHD). They further found that TMAO induces M1 polarization of bone marrow–derived macrophages via the nucleotide-binding oligomerization domain–like receptor protein 3 (NLRP3). TMAO is
Eiko, Hayase, Robert R, Jenq
openaire +2 more sources
EXCLI Journal : Experimental and Clinical Sciences, 2022 Trimethylamine N-oxide (TMAO) is a biomarker of cardiovascular risk and may enhance the progression of atherosclerosis. The aim of the study was to determine whether there are sex-specific differences in TMAO concentrations before and after cardiac ...
Andreas Baranyi +13 more
doaj +1 more source
Science immunology, 2022 The composition of the gut microbiome can control innate and adaptive immunity and has emerged as a key regulator of tumor growth, especially in the context of immune checkpoint blockade (ICB) therapy.
Gauri Mirji +13 more
semanticscholar +1 more source
TMAO-Protein Preferential Interaction Profile Determines TMAO’s Conditional In Vivo Compatibility [PDF]
Biophysical Journal, 2016 Trimethylamine N-oxide (TMAO) exemplifies how Nature uses the solute effect as a simple chemical strategy to cope with hydrodynamic pressure or urea stress to maintain proteostasis. It is a gut-microbe-generated metabolite that strongly promotes the development of atherosclerosis. It remains unclear how TMAO exerts its effects.
Jiang, Hong, Shangqin, Xiong
openaire +2 more sources