Results 121 to 130 of about 6,153 (212)

Context-dependent compensation among phosphatidylserine-recognition receptors [PDF]

, 2017
Phagocytes express multiple phosphatidylserine (PtdSer) receptors that recognize apoptotic cells. It is unknown whether these receptors are interchangeable or if they play unique roles during cell clearance.
Han, Claudia Z, Lee, Chang Sup, Lysiak, Jeffrey J, Onengut-Gumuscu, Suna, Palczewski, Krzysztof, Penberthy, Kristen K, Perry, Justin SA, Ravichandran, Kodi, Raymond, Michael H, Rival, Claudia, Shankman, Laura S, Zhang, Jianye   +11 more
core   +3 more sources

Modulation of TMEM16A-Channel Activity as Ca2+ Activated Cl− Conductance via the Interaction With Actin Cytoskeleton in Murine Portal Vein

Journal of Pharmacological Sciences, 2014
.: TMEM16A is a major component of Ca2+-activated Cl− channel (CaCC) conductance in murine portal vein smooth muscle cells (mPVSMCs). Here, the regulation of CaCC activity by the actin cytoskeleton was examined in mPVSMCs.
Junya Ohshiro, Hisao Yamamura, Yoshiaki Suzuki, Yuji Imaizumi   +3 more
doaj   +1 more source

TMEM16A Potentiation: Possible Drawbacks

American Journal of Respiratory and Critical Care Medicine, 2020
Andrea Olschewski, Chandran Nagaraj, Diana Zabini, Bence M. Nagy, Grazyna Kwapiszewska, Horst Olschewski   +5 more
openaire   +2 more sources

Pharmacological properties of native CaCCs and TMEM16A [PDF]

Channels, 2014
Kenton M, Sanders, Kate, O'Driscoll, Normand, Leblanc   +2 more
openaire   +2 more sources

Molecular basis of PIP2-dependent regulation of the Ca2+-activated chloride channel TMEM16A

Nature Communications, 2019
The calcium-activated chloride channel (CaCC) TMEM16A plays crucial roles in regulating neuronal excitability and muscle contraction. Here authors show that phosphatidylinositol (4,5)-bisphosphate (PIP2) regulates TMEM16A channel activation and ...
Son C. Le, Zhiguang Jia, Jianhan Chen, Huanghe Yang   +3 more
doaj   +1 more source

Sarcolemmal Ca2+-entry through L-type Ca2+ channels controls the profile of Ca2+-activated Cl- current in canine ventricular myocytes [PDF]

, 2020
Baczkó, István, Bányász, Tamás, Csernoch, László, Dienes, Beatrix, Gönczi, Mónika, Hegyi, Bence, Horváth, Balázs, Kistamás, Kornél, Magyar, János, Nánási, Péter Pál, Seprényi, György, Szentandrássy, Norbert, Varró, András, Váczi, Krisztina   +13 more
core   +1 more source

Renal Cyst Fluid From Human Polycystic Kidney Disease Patients Stimulates Cl- Transport: Active Factor and Cl- Channels [PDF]

, 2011
poster abstractAutosomal dominant polycystic kidney disease (ADPKD) is characterized by the slow growth of fluid-filled cysts predominately in the kidney and in liver bile ducts.
Bacallao, Robert L., Blacklock, Brenda, Blazer-Yost, Bonnie L., Gattone, Vincent H.   +3 more
core  

Modulation of TMEM16A channel activity by the von Willebrand factor type A (VWA) domain of the calcium-activated chloride channel regulator 1 (CLCA1) [PDF]

, 2017
Berry, Kayla N, Brett, Tom J, Nichols, Colin G, Sala-Rabanal, Monica, Yurtsever, Zeynep   +4 more
core   +2 more sources

Multi-Cancer Computational Analysis Reveals Metastasis-Associated Variant of Desmoplastic Reaction Involving INHBA and THBS2 [PDF]

, 2010
Despite extensive research, the details of the metastasis-associated biological mechanisms are largely unknown. Here, we analyze data from multiple cancers using a novel computational method identifying sets of genes whose coordinated overexpression ...
Dimitris Anastassiou, Hoon Kim, John Watkinson, Vinay Varadan   +3 more
core   +1 more source

MicroRNA-381 inhibits the metastasis of gastric cancer by targeting TMEM16A expression [PDF]

, 2017

core   +1 more source