Results 171 to 180 of about 6,153 (212)

DTIAM: a unified framework for predicting drug-target interactions, binding affinities and drug mechanisms. [PDF]

Nat Commun
Lu Z, Song G, Zhu H, Lei C, Sun X, Wang K, Qin L, Chen Y, Tang J, Li M.   +9 more
europepmc   +1 more source

Tamsulosin ameliorates bone loss by inhibiting the release of Cl^- through wedging into an allosteric site of TMEM16A. [PDF]

Proc Natl Acad Sci U S A
Li S, Sun W, Li S, Zhu L, Guo S, He J, Li Y, Tian C, Zhao Z, Yu T, Li J, Zhang Y, Hai Y, Wang J, Zheng Y, Wang R, Hu X, Ling S, Li H, Li Y.   +19 more
europepmc   +1 more source

Human induced pluripotent stem cells for in vitro modeling of impaired mucociliary clearance in cystic fibrosis lung disease. [PDF]

Stem Cell Res Ther
Klassen MC, Balázs A, Zöllner J, Cleve N, Czichon L, von Schledorn L, Hegermann J, Nawroth JC, Roth D, Mielenz M, Hedtfeld S, Stanke F, Rubil T, Ius F, Jonigk D, Hanrahan JW, Ruhparwar A, Olmer R, Mall MA, Merkert S, Martin U.   +20 more
europepmc   +1 more source

Distinct modulation of calcium-activated chloride channel TMEM16A by drug-binding sites. [PDF]

Proc Natl Acad Sci U S A
Roh JW, Gee HY, Wainger B, Kim WK, Lee W, Nam JH.   +5 more
europepmc   +1 more source

TMEM16A Activation Inhibits Autophagy in Dorsal Root Ganglion Cells, Which is Associated with the p38 MAPK/mTOR Pathway. [PDF]

Cell Mol Neurobiol
Yang S, Shang H, Zhang Y, Qiu J, Guo Z, Ma Y, Lan Y, Cui S, Tong H, Li G.   +9 more
europepmc   +1 more source

Is the SPLUNC1-Orai1 axis a critical determinant of lung health? [PDF]

Biochem Soc Trans
Tarran R.
europepmc   +1 more source

The emerging role of transmembrane proteins in tumorigenesis and therapy. [PDF]

Transl Cancer Res
Shen C, Han X, Liu Q, Lu T, Wang W, Wang X, Ou Z, Zhang S, Cheng X.   +8 more
europepmc   +1 more source

Natural bioactive molecules and chemotherapeutics synergism for enhanced cancer therapy. [PDF]

Nutr Metab (Lond)
Hashemi M, Heshmatzad K, Shahsavan G, Tavakolpour V, Komeilie Esfahani S, Karimi P, Beikzadeh N, Mashhadikhan S, Nasirzade S, Vasheghani Farahani A, Zali N, Cho WC, Taheriazam A, Maghrebi-Ghojogh E, Alimohammadi M, Rahimzadeh P, Hushmandi K, Entezari M.   +17 more
europepmc   +1 more source

Ciliary Ion Channels in Polycystic Kidney Disease. [PDF]

Cells
Alshriem LA, Buqaileh R, Alorjani Q, AbouAlaiwi W.   +3 more
europepmc   +1 more source

Spatiotemporal dynamics of brain pericytes in ischemic stroke. [PDF]

J Neuroinflammation
Zhong X, Ye Z, Liu L, Hui Z, Wang S, Zhang A, Zhu G, Zhao F, Li M, Zhang Z, Hu Y.   +10 more
europepmc   +1 more source