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Tocotrienol and cancer metastasis
BioFactors, 2016AbstractTumor metastasis involves some of the most complex and dynamic processes in cancer, often leading to poor quality of life and inevitable death. The search for therapeutic compounds and treatment strategies to prevent and/or manage metastasis is the ultimate challenge to fight cancer.
Leanne, De Silva +3 more
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Tocotrienols in Cardioprotection
2007Tocotrienols, a group of Vitamin E stereoisomers, offer many health benefits including their ability to lower cholesterol levels, and provide anticancer and tumor-suppressive activities. Several recent studies determined the cardioprotective abilities of tocotrienols, although the number is only 1% compared to the study with tocopherols.
Samarjit, Das +2 more
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Distribution of Tocotrienols in Rats Fed a Rice Bran Tocotrienol Concentrate
Bioscience, Biotechnology, and Biochemistry, 2007To examine the distribution of rice bran tocotrienol (T3), we gave rice bran T3 to rats after considering an acceptable daily intake of vitamin E for humans. Male SD rats (5 weeks of age) were fed for 3 weeks on a commercial diet containing 6.4 mg of vitamin E per 100 g wt and additively received vitamin E or the vehicle (vitamin E-free corn oil) by ...
Yuki, Kawakami +3 more
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Tocotrienols and Cardiovascular Health
Current Pharmaceutical Design, 2011This review emphasizes the effects of tocotrienols on the risk factors for atherosclerosis, plaque instability and thrombogenesis, and compares these effects with tocopherol. Tocotrienols reduce serum lipids and raise serum HDL-C. Alpha-tocopherol, on the other hand, has no effect on serum lipids.
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Anti-angiogenic Activity of Tocotrienol
Bioscience, Biotechnology, and Biochemistry, 2003The anti-angiogenic property of vitamin E compounds, with particular emphasis on tocotrienol, has been investigated in vitro. Tocotrienol, but not tocopherol, inhibited both the proliferation and tube formation of bovine aortic endothelial cells, with delta-tocotrienol appearing the highest activity.
Hitoshi, Inokuchi +5 more
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Tocotrienol Distribution in Foods: Estimation of Daily Tocotrienol Intake of Japanese Population
Journal of Agricultural and Food Chemistry, 2010Tocotrienol (T3) is an unsaturated form of natural vitamin E that has been focused on because of its potential health benefits (i.e., antioxidative, antihypercholesterolemic, and antiangiogenic effects). The presence of T3 in some plant sources (e.g., rice bran and palm oil) is known, but its distribution in other edible sources and its daily intake ...
Phumon, Sookwong +6 more
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Circular dichroism of tocopherols versus tocotrienols
Chirality, 2008AbstractVitamin E is an essential nutrient of still increasing economic importance. Vitamin E derivatives include many nonracemic chiral compounds whose chirooptical characterization is scarcely described in the literature. We report the CD spectra of δ‐tocopherol and its unsaturated analog δ‐tocotrienol. TDDFT calculations demonstrate that the weak CD
MAZZINI F +4 more
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Bioscience, Biotechnology, and Biochemistry, 2010
To determine the bioavailability of tocotrienol complex with gamma-cyclodextrin, the effects of tocotrienol/gamma-cyclodextrin complex on tocotrienol concentration in rat plasma and tissues were studied. Rats were administered by oral gavage an emulsion containing tocotrienol, tocotrienol with gamma-cyclodextrin, or tocotrienol/gamma-cyclodextrin ...
Saiko, Ikeda +7 more
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To determine the bioavailability of tocotrienol complex with gamma-cyclodextrin, the effects of tocotrienol/gamma-cyclodextrin complex on tocotrienol concentration in rat plasma and tissues were studied. Rats were administered by oral gavage an emulsion containing tocotrienol, tocotrienol with gamma-cyclodextrin, or tocotrienol/gamma-cyclodextrin ...
Saiko, Ikeda +7 more
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[Progression of tocotrienols].
Wei sheng yan jiu = Journal of hygiene research, 2004Tocotrienols is an isoform of tocopherols. Tocotrienols consists of a chromanol nucleus and a lipophilic isoprenoid chain. Tocotrienols were found in high concentrations in palm oil and rice bran. Its discovery was mainly antioxidant and resistant to lipid peroxidation.
Wenguang, Sun, Yageng, Yan, Fengli, Dong
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Tocotrienol Fortification in Eggs
2013In 1922, tocopherol (Toc) was discovered in green leafy vegetables as a micronutrient essential for reproduction [1]. More than 40 years later, tocotrienol (T3) was isolated from latex [2]. Structurally, these two vitamin E differ only in their side chains (Fig. 21.1).
Kiyotaka Nakagawa +2 more
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