Results 171 to 180 of about 233,587 (310)

Toll-Like Receptors Confer Responsiveness to Lipopolysaccharide fromPorphyromonas gingivalisin Human Gingival Fibroblasts

, 2000
Koichi Tabeta, Kazuhisa Yamazaki, Sachiko Akashi, Kensuke Miyake, Hidefumi Kumada, Toshio Umemoto, Hiromasa Yoshie   +6 more
openalex   +1 more source

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

Advanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu, Jingchun Shi, Heung‐Lam Mok, Cheng Lyu, Junbang Chen, Chunhua Huang, Hongyan Qin, Chengyuan Lin, Hor‐Yue Tan, Zhaoxiang Bian   +9 more
wiley   +1 more source

Modulation of the Toll-like Receptor Pathway in Ovine Endometria During Early Pregnancy. [PDF]

Animals (Basel)
Yu G, Song M, Wu C, Ma X, Zhang L, Yang L.   +5 more
europepmc   +1 more source

Toll-like receptors (TLRs) signalling and expression pattern [PDF]

, 2001
Marta Muzio, Alberto Mantovani
openalex   +1 more source

Adiponectin Assists Thrombopoietic Agents in ITP Treatment by Enhancing Myosin‐9/Rab6A‐Mediated Trafficking of c‐Mpl in MKs

Advanced Science, EarlyView.
This study revealed that adiponectin facilitates the therapeutic efficiency of thrombopoietic agents by stimulating the membrane trafficking of c‐Mpl in MKs, which provides a point for ITP therapy. Moreover, a novel c‐Mpl trafficking mechanism based on the Myosin‐9/Rab6A complex is constructed. These findings provide new insights into the applicability
Xin Zhao, Huixian Ma, Guosheng Li, Jilong Xiao, Zhiyu Shi, Mingying Li, Xinguang Liu, Tao Sun, Chunyan Ji   +8 more
wiley   +1 more source

Toll like receptor 2 mediated exacerbation of sepsis associated acute kidney injury by renal congestion in mice. [PDF]

Sci Rep
Nakamura I, Umehara M, Yagi-Tomita A, Yamamoto S, Sawai S, Nakamura M, Minamida A, Yamauchi-Sawada H, Sunahara Y, Matoba Y, Okuno-Ozeki N, Nakai K, Nakata T, Kitani T, Yamashita N, Komaki K, Kirita Y, Tamagaki K, Matoba S, Kusaba T.   +19 more
europepmc   +1 more source

Toll-like Receptors as Sensors of Pathogens [PDF]

, 2001
Mikko Hallman, Mika Rämet, R. Alan B. Ezekowitz   +2 more
openalex   +1 more source

USP45 Represses Melanoma Development by Deubiquitinating and Stabilizing Tumor Suppressor MRGPRF

Advanced Science, EarlyView.
USP45 acts as a melanoma suppressor by stabilizing MRGPRF, which weakens the PI3K/AKT pathway, suppresses tumor growth, and reduces melanoma cell migration and invasion. Abstract Melanoma, a highly malignant skin cancer, has seen a rising incidence and death toll. MRGPRF is a novel melanoma suppressor that inhibits the PI3K/AKT pathway.
Wancong Zhang, Liyun Chen, Jing Zhao, Aiwei Ma, Wenqi Shi, Yiwen Zhang, Zixuan Tang, Jiarui Guo, Zaihua Xu, Jianda Zhou, Shijie Tang   +10 more
wiley   +1 more source

Cell surface Toll-like receptor polymorphisms influence <i>Bartonella</i> and ectoparasite infections in striped hamsters. [PDF]

iScience
Lun X, Yue Y, Wang Y, Li G, Zhao N, Meng F, Liu Q, Liu P, Wang Z, Wang Z, Song X, Wang J, Liang Y, Lu L.   +13 more
europepmc   +1 more source

A Novel Polymorphism in the Toll-Like Receptor 2 Gene and Its Potential Association with Staphylococcal Infection

, 2000
Eva Lorenz, Jean Paul Mira, Kristyn L. Cornish, Nancy C. Arbour, David A. Schwartz   +4 more
openalex   +1 more source