Results 171 to 180 of about 238,767 (310)

Interfacial Coordination‐Engineered Emulgel Modulates the Osteo‐Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway‐Induced Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of HIPPE‐QU‐mediated periodontal regeneration. a) Fabrication process and microstructure of HIPPE‐QU. b) Antimicrobial and immunomodulatory HIPPE‐QU hydrogel for periodontal regeneration. HIPPE‐QU hydrogel co‐delivers HA‐Cu, GNPs, and QU, providing antimicrobial effects and reprogramming the immune microenvironment to promote ...
Hui Zhang, Xiao Huang, Rui Chen, Weimin Lin, Linke Li, Xi Peng, Xinxi Yang, Xingyu Chen, Tailin Guo, Jie Weng, Jianshu Li, Quan Yuan, Huan Tan, Mengyuan Wang   +13 more
wiley   +1 more source

Light-triggered toll-like receptor activation in a nanoscale metal-organic framework for synergistic PDT and cancer immunotherapy. [PDF]

Chem Sci
Mao Y, Tillman L, Jiang X, Bian W, Wang C, Fromme T, Weichselbaum RR, Lin W.   +7 more
europepmc   +1 more source

Roles of Toll‐like receptors in innate immune responses [PDF]

, 2001
Kiyoshi Takeda, Shizuo Akira
openalex   +1 more source

Targeted Enrichment of Engineered Bacteria on Triple‐Negative Breast Cancer Turns Immunologically Cold Tumors Hot

Advanced Science, EarlyView.
In this study, an “all‐in‐one” engineered anaerobic bacterial system (PDAEcN/COS) is developed for the treatment of immunologically “cold” TNBC. This nanoplatform is capable of colonizing tumor cell surfaces and implementing “self‐blocking” of immune checkpoints, while simultaneously suppressing tumor cells' “don't eat me” signals and delivering “eat ...
Xuanxiang Zhai, Xiaoyi Shi, Xiao Liu, Xiaotong Gu, Wenting Li, Xiangjun Chen, Wei Hong   +6 more
wiley   +1 more source

Necrotizing Enterocolitis: A Comprehensive Review on Toll-like Receptor 4-Mediated Pathophysiology, Clinical, and Therapeutic Insights. [PDF]

Biomedicines
Ishiyama A, Jang HS, Dintaman JM, Duess JW, Tragesser C, Sodhi CP.   +5 more
europepmc   +1 more source

Toll-Like Receptors Confer Responsiveness to Lipopolysaccharide fromPorphyromonas gingivalisin Human Gingival Fibroblasts

, 2000
Koichi Tabeta, Kazuhisa Yamazaki, Sachiko Akashi, Kensuke Miyake, Hidefumi Kumada, Toshio Umemoto, Hiromasa Yoshie   +6 more
openalex   +1 more source

Circulating cell wall components derived from gram‐negative, not gram‐positive, bacteria cause a profound induction of the gene‐encoding Toll‐like receptor 2 in the CNS [PDF]

, 2001
Nathalie Laflamme, Geneviève Soucy, Serge Rivest   +2 more
openalex   +1 more source

Integrated Metabolic and Inflammatory Clustering Reveals Distinct Risk Profiles for Digestive Diseases

Advanced Science, EarlyView.
This study analyzes 398 432 participants, identifying four distinct metabolic‐inflammatory subtypes. These subtypes show a significant association with digestive disease risk. Cluster‐associated metabolite signatures partially explain this link. Machine learning models using these metabolites accurately predict risk for ten digestive diseases. Key risk
Zhenhe Jin, Qichen Chen, Liangfeng Zhou, Kexin Ye, Zhaoxue Liu, Wenxi Jiang, Linwen Luo, Yize Wang, Xiaohua Ye, Chaohui Yu, Zhe Shen   +10 more
wiley   +1 more source

Downregulation of Toll-Like Receptor Gene Expression Among Hepatitis B Virus-Positive Human Patients. [PDF]

Cureus
Hussein TH, Al-Yami A, Mtiraoui N, Gharbi J, Ben M'hadheb M.   +4 more
europepmc   +1 more source

Molecular Cloning and Functional Characterization of Chicken Toll-like Receptors [PDF]

, 2001
Aya Fukui, Naokazu Inoue, Misako Matsumoto, Midori Nomura, Kazuhiko Yamada, Yoichi Matsuda, Kumao Toyoshima, Tsukasa Seya   +7 more
openalex   +1 more source