Results 191 to 200 of about 233,587 (310)

Escherichia coli P fimbriae utilize the Toll‐like receptor 4 pathway for cell activation [PDF]

, 2001
Björn Frendéus, Caroline Wachtler, Maria Hedlund, Hans Fischer, Patrik Samuelsson, Majlis Svensson, Catharina Svanborg   +6 more
openalex   +1 more source

Regulation of Neuroinflammation by Microglial DUBA‐IRAK1‐IKKβ Signaling Loop

Advanced Science, EarlyView.
The protein levels of deubiquitinating enzyme A (DUBA) are rapidly upregulated in microglia after activation of Toll‐like receptor 4 (TLR4). In turn, DUBA potentiates TLR4‐induced proinflammatory signal transduction in microglia by stabilizing interleukin‐1 receptor activated kinase 1 (IRAK1) through K48 deubiquitination.
Zhenhu Zhu, Zhongding Li, Kate Lykke Lambertsen, Zijun Cao, Meng Chen, Yanqi Xu, Bettina Hjelm Clausen, Keshuo Jin, Yiting Lu, Fuqi Mei, Xue Du, Kangmin Chen, Huiyuan Bai, Xian Su, Bincheng Zhou, Baohua Liu, Ran Li, Chaoqun Wang, Yuhua Li, Xiang Cai, Dirk Schlüter, Weihong Song, Xu Wang   +22 more
wiley   +1 more source

Toll-like Receptor Activation Remodels the Polyamine and Tryptophan Metabolism in Porcine Macrophages. [PDF]

Metabolites
Zhang M, Du L, Shen Y, Bin P.
europepmc   +1 more source

Activated human hepatic stellate cells express CD14 and toll like receptors 2 and 4 (TLR-2, TLR-4)

, 2000
Claus Hellerbrand, WE Thasler, Cornelia M. Gelbmann, Stijn Lambrecht, Katrin Letschert, G. Lock, J. Schoelmerich   +6 more
openalex   +1 more source

Endocytosed HSP60s Use Toll-like Receptor 2 (TLR2) and TLR4 to Activate the Toll/Interleukin-1 Receptor Signaling Pathway in Innate Immune Cells [PDF]

, 2001
R. Martin Vabulas, Parviz Ahmad‐Nejad, Clarissa da Costa, Thomas Miethke, Carsten J. Kirschning, Hans Häcker, Hermann Wagner   +6 more
openalex   +1 more source

A Novel nor@DHB Matrix for Direct Microbial Analysis in Lung Cancer Tissues

Advanced Science, EarlyView.
Integrated matrix‐assisted laser desorption/ionization mass spectrometry workflow quantifies intratumoral microbes in lung cancer through lipopolysaccharide/lipid A extraction from biopsies. The novel ionic matrix called norharmane conjugated to 2,5‐dihydroxybenzoic acid enhances lipid A ionization, enabling direct detection of bacterial genera ...
Liang Shan, Xin Xu, Lin Huang, Dan Li, Yiran Deng, Xiangfei Xue, Susu Guo, Yiman Huang, Xiao Zhang, Yongchun Yu, Lifang Ma, Kun Qian, Jiayi Wang   +12 more
wiley   +1 more source

Toll-like receptor 2 activation of early divided bovine embryo promotes its viability and development competence in vitro. [PDF]

Sci Rep
Ma D, Akthar I, Hashimoto T, Marey MA, Kusama K, Imakawa K, Shimada M, Miyamoto A.   +7 more
europepmc   +1 more source

Activation of Toll-Like Receptor-2 by Glycosylphosphatidylinositol Anchors from a Protozoan Parasite [PDF]

, 2001
Marco Antônio Campos, Igor C. Almeida, Osamu Takeuchi, Shizuo Akira, Eneida P. Valente, Daniela O. Procópio, Luiz R. Travassos, Jason A. Smith, Douglas T. Golenbock, Ricardo T. Gazzinelli   +9 more
openalex   +1 more source

BCG‐Derived Outer Membrane Vesicles Induce TLR2‐Dependent Trained Immunity to Protect Against Polymicrobial Sepsis

Advanced Science, EarlyView.
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong, Wenyan Hao, Lingqi Xu, Yingyi Yang, Zhenzhen Dong, Peng Pan, Zhenjiang Bai, Jie Huang, Kaidi Yang, Zhu Jin, Rui Kang, Qiang Shan, Jiang huai Wang, Zijian Zhou, Daolin Tang, Jian Wang, Huiting Zhou   +16 more
wiley   +1 more source

Toll-like receptor 4 pathway evolutionary trajectory and functional emergence. [PDF]

Front Immunol
Verma S, Sowdhamini R.
europepmc   +1 more source