Results 201 to 210 of about 238,767 (310)

Investigation into the Pancreatic Pathogenesis of SFTSV across Multiple Levels

Advanced Science, EarlyView.
A retrospective analysis revealed that 17.6% of severe fever with thrombocytopenia syndrome (SFTS) patients met the diagnostic criteria for clinically confirmed pancreatitis. Using human pancreatic organoids and murine models demonstrated that SFTSV exhibits a specific pancreatic tropism, leading to cell death and initiating a strong inflammatory ...
Xiaohan Liu, Zhihao Xu, Yilun Tong, Changtai Wang, Yueqi Yao, Yujie Diao, Jingyuan Ma, Shijun Zhou, Yinan Du, Zhenhua Zhang, Gang Xu   +10 more
wiley   +1 more source

Reduced Bone Quality of Sacrum and Lumbal Vertebrae Spongiosa in Toll-like Receptor 2- and Toll-like Receptor 4-Knockout Mice: A Blinded Micro-Computerized Analysis. [PDF]

Biomolecules
Roth K, Pallua JD, Degenhart G, De Zordo T, Kremser C, Reif C, Streif W, Schirmer M.   +7 more
europepmc   +1 more source

Activation of toll-like receptors by microbial lipoproteins: Role in host defense☆ [PDF]

, 2001
Robert L. Modlin
openalex   +1 more source

Illuminating the Unseen and Targeting the Untreatable: Aggregation‐Induced Emission Nanoparticles as Intelligent, Immune‐Compatible Tools for Precision Cancer Theranostics

Aggregate, EarlyView.
Rationally engineered AIE nanoparticles can unite deep‐tissue imaging, photodynamic therapy, photothermal therapy, and immune microenvironment reprogramming. Through precise photophysical tuning and targeted delivery, these intelligent nanoplatforms enable real‐time monitoring, potent tumor eradication, and immune activation, offering a versatile and ...
Quazi T. H. Shubhra, Robert Musiol, Huachun Pan, Qiang Cai, Xiaosong He, Xiaojun Cai   +5 more
wiley   +1 more source

Toll-like Receptor 9 Mediates Epstein-Barr Virus-Aggravated Inflammation in a Mouse Model of Inflammatory Bowel Disease. [PDF]

Biomedicines
Nour Eddine HF, Kassem AM, Salhab Z, Sherri N, Moghabghab K, Mohsen Z, Naim G, Mahmoud S, Jurjus A, Hashash JG, Rahal EA.   +10 more
europepmc   +1 more source

Activation of NF-κB by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK–IKKα/β–IκBα and MKK3/6–p38 MAP kinase signaling pathways in epithelial cells [PDF]

, 2001
Tsuyoshi Shuto, Haidong Xu, Beinan Wang, Jiahuai Han, Hirofumi Kai, Xin-Xing Gu, Timothy F. Murphy, David Lim, Jiandong Li   +8 more
openalex   +1 more source

Parents' WhatsApp coping resources in the context of ongoing political conflicts: An ecological exploration

American Journal of Community Psychology, EarlyView.
Abstract Mobile technologies have become significant resources for crisis communication and social support in recent years. However, despite empirical evidence pointing to the centrality of these technologies for parenthood in everyday life, it is yet unknown how parents' coping resources play a role in the digital environment.
Daphna Yeshua‐Katz, Stav Shapira, Orna Braun‐Lewensohn   +2 more
wiley   +1 more source

Identification of Toll-like receptor 4 (Tlr4) as the sole conduit for LPS signal transduction: genetic and evolutionary studies

, 2001
Bruce Beutler, Xin Du, Alexander Poltorak   +2 more
openalex   +1 more source

The Diagnosis That Arrived Decades Late: Living Without and Then With Myhre Syndrome

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MIM #139210) is a rare multisystem disorder first described in 1981, characterized by short stature, neurodevelopmental delay, joint contractures, and cardiopulmonary complications. Its molecular basis, recurrent pathogenic variants in SMAD4, was not discovered until 2011. This narrative is based on a review of medical records,
Abdallah F. Elias
wiley   +1 more source

Modulation of the Toll-like Receptor Pathway in Ovine Endometria During Early Pregnancy. [PDF]

Animals (Basel)
Yu G, Song M, Wu C, Ma X, Zhang L, Yang L.   +5 more
europepmc   +1 more source