Results 221 to 230 of about 233,587 (310)

In Vitro Effects of Lipopolysaccharide on Rabbit Sperm: Toll-like Receptor 4 Expression, Motility, and Oxidative Status. [PDF]

open access: yesAntioxidants (Basel)
Quattrone A   +22 more
europepmc   +1 more source

A Novel Pathway Regulating Lipopolysaccharide-Induced Shock by ST2/T1 Via Inhibition of Toll-Like Receptor 4 Expression

open access: bronze, 2001
Matthew J. Sweet   +8 more
openalex   +1 more source

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap‐DNAs and Alleviating Pulmonary Fibrosis

open access: yesAdvanced Science, EarlyView.
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du   +7 more
wiley   +1 more source

Absence of Toll-Like Receptor 4 Explains Endotoxin Hyporesponsiveness in Human Intestinal Epithelium

open access: bronze, 2001
Sandhia Naik   +4 more
openalex   +1 more source

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

open access: yesAdvanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu   +7 more
wiley   +1 more source

Toll-Like Receptor Signaling in Liver Diseases

open access: yesGastroenterology Research and Practice, 2010
Gyongyi Szabo   +4 more
doaj   +1 more source

API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs

open access: yesAdvanced Science, EarlyView.
Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy