Results 81 to 90 of about 238,767 (310)
Toll-like Receptor 9 in Breast Cancer
Frontiers in Immunology, 2014 Toll-like receptor 9 (TLR9) is a cellular DNA receptor of the innate immune system. DNA recognition via TLR9 results in an inflammatory reaction, which eventually also activates a Th1-biased adaptive immune attack.
Katri eSelander +2 more
doaj +1 more source
Human Toll-Like Receptors Mediate Cellular Activation by Mycobacterium tuberculosis [PDF]
, 1999 Terry K. Means +5 more
openalex +1 more source
Toll-Like Receptors in Skin [PDF]
Advances in Dermatology, 2008 TLRs have emerged as a major class of PRRs that are involved in detecting invading pathogens in the skin and initiating cutaneous immune responses. TLRs are expressed on many different cell types in the skin, including keratinocytes and Langerhans cells in the epidermis.
openaire +3 more sources
Advanced Materials, EarlyView.This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and antiinflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai +6 more
wiley +1 more source
LncRNA CRNDE triggers inflammation through the TLR3-NF-κB-Cytokine signaling pathway
Tumor Biology, 2017 Colorectal neoplasia differentially expressed (CRNDE), an oncogene, is highly expressed in many tumor cells and affects cellular proliferation, migration, invasion, and apoptosis. Its function and mechanism of action is a research hotspot. In this study,
Haowen Li +5 more
doaj +1 more source
The Molecular Mechanism of B Cell Activation by toll-like Receptor Protein RP-105 [PDF]
, 1998 Vivien W. Chan +9 more
openalex +1 more source
Advanced Materials, EarlyView.Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier +10 more
wiley +1 more source
Cutting Edge: Endotoxin Tolerance in Mouse Peritoneal Macrophages Correlates with Down-Regulation of Surface Toll-Like Receptor 4 Expression [PDF]
, 2000 Fumiko Nomura +10 more
openalex +1 more source
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Advanced Materials, EarlyView.Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang +4 more
wiley +1 more source
Toll-Like Receptor 3 in Liver Diseases
Gastroenterology Research and Practice, 2010 Toll-like receptor 3 (TLR3) is a member of the TLR family that can recognize double-stranded RNA (dsRNA), playing an important role in antiviral immunity.
Shi Yin, Bin Gao
doaj +1 more source