Results 321 to 330 of about 363,419 (348)

Nicotine Treatment Improves Toll-Like Receptor 2 and Toll-Like Receptor 9 Responsiveness in Active Pulmonary Sarcoidosis

Chest, 2013
New evidence links nicotine to the regulation of T cell-mediated inflammation via a 7 nicotinic cholinergic receptor activation, and chronic nicotine exposure (smoking) reduces the incidence of granulomatous diseases. We sought to determine whether nicotine treatment was well tolerated while effectively normalizing immune responses in patients with ...
Mark W, Julian, Guohong, Shao, Larry S, Schlesinger, Qin, Huang, David G, Cosmar, Nitin Y, Bhatt, Daniel A, Culver, Robert P, Baughman, Karen L, Wood, Elliott D, Crouser   +9 more
openaire   +2 more sources

Reduced soluble Toll-like receptors 2 in type 2 diabetes

Archives of Physiology and Biochemistry, 2017
Soluble forms of Toll-like receptors (sTLR) 2 and 4 exert negative regulatory control on membrane-bound receptor activation. The study estimates the sTLR2 and sTLR4's serum levels in type 2 diabetes (T2D) and evaluates their relationship with metabolic and inflammatory parameters.Sixty three patients with T2D and 25 controls were enrolled.
Emanuela, Zaharieva, Tsvetelina, Velikova, Adelina, Tsakova, Zdravko, Kamenov   +3 more
openaire   +2 more sources

Toll-like receptor 2-mediated human B cell differentiation

Clinical Immunology, 2006
Human B cells likely have a major role in the adjuvant activity of Toll-like receptor (TLR) 9 agonists by enhancing innate and adaptive immune responses. As several TLR2 ligands are promising vaccine adjuvant candidates, our aim was to characterize the effects of TLR2 stimulation on human B cell activation and differentiation using cells derived from ...
Lisa M, Ganley-Leal, Xiuping, Liu, Lee M, Wetzler   +2 more
openaire   +2 more sources

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

Nature, 1998
Vertebrates and invertebrates initiate a series of defence mechanisms following infection by Gram-negative bacteria by sensing the presence of lipopolysaccharide (LPS), a major component of the cell wall of the invading pathogen. In humans, monocytes and macrophages respond to LPS by inducing the expression of cytokines, cell-adhesion proteins, and ...
R B, Yang, M R, Mark, A, Gray, A, Huang, M H, Xie, M, Zhang, A, Goddard, W I, Wood, A L, Gurney, P J, Godowski   +9 more
openaire   +2 more sources

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023

exaly  

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Boris Böll, Victoria Metaxa   +2 more
exaly  

Breast Cancer Statistics, 2022

Ca-A Cancer Journal for Clinicians, 2022
Hyuna Sung, Kimberly D Miller, Rebecca L Siegel   +2 more
exaly  

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly  

Toll-Like Receptor 2

2016
Prasannavenkatesh Durai, Sangdun Choi
openaire   +1 more source